Version 2.78

Part Description

LP14853-3   Varicella zoster virus
Varicella zoster virus (VZV) is a double-stranded alphaherpesvirus that causes seasonal outbreaks of chickenpox and shingles in non-immunized populations. VZV is highly infectious and is transmitted by contact with the ruptured fluid filled blisters and respiratory secretions of infected individuals. Immunity post infection is usually lifelong though the latent virus inhabits the sensory nerve ganglia where it can reactivate causing shingles when immunity declines with aging.[http://jvi.asm.org/content/88/24/13936.full] In the over fifty strains of VZV that have been sequenced it has been found that a single nucleotide polymorphism occurs about every 100 bases. The patterns of polymorphisms in VZV correlate with different geographical regions of infection and is the basis for the classification of viral clades.[https://grose.lab.uiowa.edu/vzv-genomes-and-evolution] Breuer proposed the nomenclature for the VZV clades as 1-5 with the suspected clades VI and VII to be confirmed later. The geographical regions associated with the seven clades are as follows:
Clades 1 and 3-represent the dominant clades of the circulating VZV in Europe and the Americas
Clades 4 and 5-found in Africa
Clade VI found in France, Italy
Clade VII exclusively isolated in the US
Clade 2-Asia from Korea, Japan, China not found in India, Nepal and Bangladesh where clades 4 and 5 were dominant
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054591/ Source: Regenstrief LOINC

Fully-Specified Name

Component
Varicella zoster virus Ab.IgM
Property
Titr
Time
Pt
System
CSF
Scale
SemiQn
Method
IF

Additional Names

Short Name
VZV IgM Titr CSF IF
Display Name
VZV IgM IF (CSF) [Titer]
Consumer Name Alpha Get Info
Varicella zoster virus (VZV; Chickenpox) IgM antibody, Spinal fluid

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 1.0m
Last Updated
Version 2.75
Order vs. Observation
Both
Common Test Rank Get Info
14385

Member of these Groups Get Info

LOINC Group Group Name
LG32750-8 Varicella zoster virus

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) anticuerpo contra virus Varicela-zoster.inmunoglobulina M:factor de dilución (titulación):punto en el tiempo:líquido cefalorraquídeo:cuantitativo:inmunofluorescencia
es-ES Spanish (Spain) Virus Varicella zoster IgM:Titulo / Factor de dilución:Punto temporal:Líquido Cefalorraquideo:Semicuantitativo:Inmunofluorescencia (IF)
Synonyms: Semicuantitativo
es-MX Spanish (Mexico) Ab.IgM del virus de la varicela zóster:Título:Punto temporal:Fluído espinal cerebral:Cuantitativo:Inmunofluorescencia (IF)
fr-CA French (Canada) Virus varicelle-zona, IgM:Titre:Temps ponctuel:LCR:SemiQn:Immunofluorescence
fr-FR French (France) Varicelle zona virus Ac IgM:Titre:Ponctuel:Liquide céphalorachidien:Semi-Quantitatif:Immunofluorescence
it-IT Italian (Italy) Varicella zoster, virus Ab.IgM:Titr:Pt:LCS:SemiQn:IF
Synonyms: Anticorpi IgM anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Microbiologia Punto nel tempo (episodio) Titolo Virus della varicella zoster
ko-KR Korean (Korea, Republic Of) 수두 대상포진 바이러스 항체.면역글로불린 M:역가:검사시점:뇌척수액:정량:면역형광
nl-NL Dutch (Netherlands) varicella-zostervirus As.IgM:titer:moment:liquor cerebrospinalis:semikwantitatief:immunofluorescentie
Synonyms: antistof; antilichaam IF Varicella zoster virus
pt-BR Portuguese (Brazil) Varicella zoster vírus Ac.IgM:Título:Pt:LCR:Qn:Imunofluorescência
Synonyms: ; VZV; Shingles; Chicken pox; Human herpesvirus 3; HHV-3; Chickenpox; Herpes zoster; VZ; Chicken pox virus; Immune globulin M; Immunoglobulin M; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Cerebral spinal fluid; Spinal Fluid; Cerebrospinal Fl; Spinal Flu; Spinal Fld; Quantitative; QNT; Quant; Quan; ACIF; FA; Fluorescent antibody; Immune fluorescence; Fluoresent; Immunoflour; Immunofluor; Immunofluorescence; IFA; Time Resolved Fluorescence; Anticomplement Immunofluorescence; TRF; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
zh-CN Chinese (China) 水痘带状疱疹病毒 抗体.IgM:滴定度:时间点:脑脊液:半定量型:免疫荧光法
Synonyms: Ab.IgM;IgM;抗体 IgM Ab;自身抗体 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 HHV-3 Ab HHV-3 Ab.IgM HHV-3 抗体 HHV-3 抗体.IgM HHV-3;VZ;VZV;人类疱疹病毒 3 型;人类疱疹病毒 III 型;带状疱疹;水痘;水痘带状疱疹;水痘病毒;Varicella zoster virus;水痘-带状疱疹病毒 IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 VZV Ab VZV Ab.IgM VZV 抗体 VZV 抗体.IgM 人类疱疹病毒 3 型 Ab 人类疱疹病毒 3 型 Ab.IgM 人类疱疹病毒 3 型抗体 人类疱疹病毒 3 型抗体.IgM 人类疱疹病毒 III 型 Ab 人类疱疹病毒 III 型 Ab.IgM 人类疱疹病毒 III 型抗体 人类疱疹病毒 III 型抗体.IgM 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 免疫球蛋白 M 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 水痘带状疱疹病毒 Ab 水痘带状疱疹病毒 Ab.IgM 水痘带状疱疹病毒 IgM 水痘病毒 Ab 水痘病毒 Ab.IgM 水痘病毒抗体 水痘病毒抗体.IgM 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液

Example Units

Unit Source
titer REGENSTRIEF
{titer} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=21596-2