Version 2.77

Part Description

LP19647-4   CDKN2B gene
The CDKN2B gene (cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)) [HGNC Gene ID:1788] is located on chromosome 9p21. This gene lies adjacent to the tumor suppressor gene CDKN2A in a region that is frequently mutated and deleted in a wide variety of tumors. This gene encodes a cyclin-dependent kinase inhibitor, which forms a complex with CDK4 or CDK6, and prevents the activation of the CDK kinases, thus the encoded protein functions as a cell growth regulator that controls cell cycle G1 progression. The expression of this gene was found to be dramatically induced by TGF beta, which suggested its role in the TGF beta induced growth inhibition. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008] [NCBI Gene ID:1030] Source: National Center for Biotechnology Information (NCBI) Gene

Fully-Specified Name

Component
CDKN2B gene deletion
Property
Arb
Time
Pt
System
Bld/Tiss
Scale
Ord
Method
Molgen

Additional Names

Short Name
CDKN2B gene Del Bld/T Ql
Display Name
CDKN2B gene del Molgen Ql (Bld/Tiss)
Consumer Name Alpha Get Info
CDKN2B gene deletion analysis, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.DEL
Type
Laboratory
First Released
Version 1.0m
Last Updated
Version 2.13
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) deleción genética CDKN2B:arbitrario:punto en el tiempo:sangre entera/tejido:ordinal:genética molecular
es-ES Spanish (Spain) Gen CDKN2B Deleción:Arbitrario:Punto temporal:Sangre o tejido:Ord:Genética molecular
es-MX Spanish (Mexico) Deleción del gen CDKN2B:Arbitrario:Punto temporal:Sangre o tejido:Ordinal:Genética molecular
fr-FR French (France) CDKN2B gène délétion:Arbitraire:Ponctuel:Sang/Tissu:Qualitatif:Biologie moléculaire
it-IT Italian (Italy) CDKN2B, gene Delezione:Arb:Pt:Sangue/Tess:Ord:Molgen
Synonyms: Arbitrario Delezione genetica Gene CDKN2B Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci
ko-KR Korean (Korea, Republic Of) CDKN2B 유전자 결손:임의적분:검사시점:전혈/조직:순위척도:분자유전
nl-NL Dutch (Netherlands) CDKN2B-gen deletie:aanwezigheid:moment:bloed of weefsel:ordinaal:moleculair genetisch onderzoek
Synonyms: CDKN2B gen molgen
pt-BR Portuguese (Brazil) CDKN2B deleção do gene:Arb:Pt:Sg/Tecido:Ord:Genética molecular
Synonyms: P15; INK4B; Multiple tumor suppressor 2; MTS2; CDK4B inhibitor; Cyclin-dependent kinase inhibitor 2B geng; Cyclin-dependent kinase 4 inhibitor B gene; Arbitrary; Point in time; Random; Bld/T; Tissue; Bld/T; Blood; WB; Whole blood; Ql; Ordinal; QL; Qualitative; Qual; Screen; PCR; Molecular genetics; Deletions; MOLPATH.DELETIONS; MOLPATH.DELETIONS; Molecular pathology
ru-RU Russian (Russian Federation) CDKN2B ген делеция:Произв:ТчкВрм:Кр/Тк:Пор:МолГен
Synonyms: Кровь Кровь или Ткань Порядковый Произвольный Ткань и мазки Точка во времени;Момент
tr-TR Turkish (Turkey) CDKN2B geni delesyon:Sç:Zmlı:Kan/Dk:Srl:Molgen
zh-CN Chinese (China) CDK2B 基因 缺失:任意型:时间点:全血/组织:序数型:分子遗传学类实验室方法
Synonyms: CDK4B 抑制剂;CDK4B 抑制因子;INK4B;MTS2;P15;多发性肿瘤抑制因子 2;多肿瘤抑制基因 2;多重肿瘤抑制因子 2;细胞周期素-依赖性激酶 4 抑制因子 B 基因;细胞周期素-依赖性激酶抑制因子 2B 基因;细胞周期蛋白-依赖性激酶 4 抑制因子 B 基因;细胞周期蛋白-依赖性激酶抑制因子 2B 基因 任意;任意的;人工型 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 全血或组织;血液/组织;血液或组织 分子病理学.基因缺失;分子病理学.缺失;分子病理学试验.基因缺失;分子病理学试验.缺失;分子病理学试验类.缺失;基因缺失;缺失 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 染色体缺失;染色体区带缺失;基因缺失;缺损;基因缺损;基因删除;删除;基因丢失 血;血液 遗传基因;遗传因子;吉恩;生物基因

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