21665-5

EGFR gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal

Active

Part Description

LP19695-3 EGFR gene
The EGFR gene (epidermal growth factor receptor) [HGNC Gene ID:3236] is located on chromosome 7p12. The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010] [NCBI Gene ID:1956] Source: National Center for Biotechnology Information (NCBI) Gene

Fully-Specified Name

Component: EGFR gene targeted mutation analysis
Property: Prid
Time: Pt
System: Bld/Tiss
Scale: Nom
Method: Molgen

Additional Names

Long Common Name: EGFR gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method Nominal
Short Name: EGFR gene Mut Anl Bld/T
Display Name: EGFR gene targeted mutation analysis Molgen Nom (Bld/Tiss)
Consumer Name Alpha Get Info: EGFR gene targeted mutation analysis, Blood or tissue specimen

Basic Attributes

Class: MOLPATH.MUT
Type: Laboratory
First Released: Version 1.0m
Last Updated: Version 2.73 (MIN)
Change Reason: Based on LOINC Committee review (June 2016), "targeted" was added to the Component to clarify that this test is looking for a specific set of mutations as described in the LOINC User Guide under the Molecular Genetics section.
Order vs. Observation: Both
Common Test Rank Get Info: 7493

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	Γονίδιο EGFR στοχευμένη ανάλυση μεταλλάξεων:Prid:Pt:Αίμα/Ιστός:Nom:Μοριακή γενετική Synonyms: Prid
es-ES	Spanish (Spain)	Gen EGFR Analisis de mutaciones:Presencia o identidad:Punto temporal:Sangre o tejido:Nom:Genética molecular
es-AR	Spanish (Argentina)	análisis de la mutación del gen EGFR:presencia o identidad:punto en el tiempo:sangre entera/tejido:Nominal:genética molecular
es-MX	Spanish (Mexico)	Análisis de mutaciones dirigidas al gen EGFR:Presencia o identidad:Punto temporal:Sangre o tejido:Nominal:Genética molecular
fr-FR	French (France)	EGFR gène mutation cible trouvée:Identification:Ponctuel:Sang/Tissu:Résultat nominal:Biologie moléculaire
it-IT	Italian (Italy)	EGFR, gene analisi di mutazione mirata:Prid:Pt:Sangue/Tess:Nom:Molgen Synonyms: Gene EGFR Genetica molecolare Mutazione genica Patologia molecolare Presenza o Identità Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci
ko-KR	Korean (Korea, Republic Of)	EGFR 유전자 돌연변이 분석:존재:검사시점:전혈/조직:명칭결과:분자유전
nl-NL	Dutch (Netherlands)	EGFR-gen doelgerichte mutatie-analyse:identificator:moment:bloed of weefsel:nominaal:moleculair genetisch onderzoek Synonyms: EGFR gen molgen targeted
pt-BR	Portuguese (Brazil)	EGFR análise de mutação genética:Ident:Pt:Sg/Tecido:Nom:Genética molecular Synonyms: V-ERB-B avian erythroblastic leukemia viral oncogene homolog; Oncogene ERBB; Epidermal growth factor receptor gene; ERBB1; Identity or presence; Point in time; Random; Bld/T; Tissue; Bld/T; Blood; WB; Whole blood; Nominal; PCR; Molecular genetics; Mut Anal; Mutations; MOLPATH.MUTATIONS; MOLPATH.MUTATIONS; Molecular pathology
ru-RU	Russian (Russian Federation)	EGFR ген исследование на мутацию:ПрИд:ТчкВрм:Кр/Тк:Ном:МолГен Synonyms: Кровь Кровь или Ткань Номинальный;Именной Присутствие или Идентификация Ткань и мазки Точка во времени;Момент
tr-TR	Turkish (Turkey)	EGFR geni Mutasyon analizi:MevcKimlik:Zmlı:Kan/Dk:Snf:Molgen
zh-CN	Chinese (China)	EGFR 基因突变分析:存在与否或特征标识:时间点:全血/组织:名义型:分子遗传学类实验室方法 Synonyms: ERBB;ERBB1;V-ERB-B 禽类成红血细胞性白血病病毒性致癌基因同源基因;V-ERB-B 禽类成红血细胞性白血病病毒致癌基因同源基因;V-ERB-B 鸟类成红血细胞性白血病病毒性癌基因同源基因;V-ERB-B 鸟类成红血细胞性白血病病毒癌基因同源基因;癌基因 ERBB;致癌基因 ERBB;表皮生长因子受体基因全血或组织;血液/组织;血液或组织分子病理学.基因突变;分子病理学.突变;分子病理学试验.基因突变;分子病理学试验.突变;分子病理学试验类.突变;基因突变;突变分子病理学;分子病理学试验分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答基因突变分析存在;存在与否;特征标识;身份;身份标识时刻;随机;随意;瞬间未作说明的组织;组织;组织 & 涂片血;血液遗传基因;遗传因子;吉恩;生物基因

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