21702-6

KRAS gene mutations found [Identifier] in Blood or Tissue by Targeted gene mutation analysis Nominal

Active

Part Description

LP19732-4 KRAS gene
The KRAS gene (Kirsten rat sarcoma viral oncogene homolog) [HGNC Gene ID:6407] is located on chromosome 12p12.1. This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008] [NCBI Gene ID:3845] Source: National Center for Biotechnology Information (NCBI) Gene

LOINC Names Get Info

Fully-Specified Name: KRAS gene mutations:Prid:Pt:Bld/Tiss:Nom:Targeted gene mutation analysis
Long Common Name: KRAS gene mutations found [Identifier] in Blood or Tissue by Targeted gene mutation analysis Nominal
Short Name: KRAS gene Mut Bld/T Mut Anl
Display Name: KRAS gene mutations found Targeted gene mutation analysis Nom (Bld/Tiss)
Consumer Name Alpha Get Info: KRAS gene mutations found, Blood or tissue specimen

Part Model Get Info

Component
KRAS gene mutations
LP451925-4
- Analyte
  KRAS gene mutations
  LP451925-4
  - Component Numerator
    KRAS gene mutations
    LP451925-4
    - Component Numerator Core
      KRAS gene
      LP19732-4
    - Component Numerator Core Suffix
      mutations
      LP452208-4
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Prid
LP6850-4
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Bld/Tiss
LP7061-7
- System Core
  Bld/Tiss
  LP7061-7
- Super System
  NULL
Scale
Nom
LP7750-5
Method
Targeted gene mutation analysis
LP95475-7

Basic Attributes

Class: MOLPATH.MUT
Type: Laboratory
First Released: Version 1.0m
Last Updated: Version 2.83 (NAM)
Change Reason: Based on LOINC Committee review (June 2016), "targeted" was added to the Component to clarify that this test is looking for a specific set of mutations as described in the LOINC User Guide under the Molecular Genetics section.
Order vs. Observation: Both
Common Test Rank Get Info: 8117

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Gen KRAS cílená mutační analýza:Přítomnost nebo identita:Časový bod:Krev/tkáň:Nominální:Molekulární genetika
de-AT	German (Austria)	Synonyms: KRAS Mutationsanalyse
el-GR	Greek (Greece)	Γονίδιο KRAS στοχευμένη ανάλυση μεταλλάξεων:Prid:Pt:Αίμα/Ιστός:Nom:Μοριακή γενετική Synonyms: MOLPATH MOLPATH.MUT Nom Prid Pt Αίμα Αίμα/Ιστός Γονίδιο Γονίδιο KRAS Ιστός Μοριακή γενετική στοχευμένη ανάλυση μεταλλάξεων
es-AR	Spanish (Argentina)	análisis de la mutación del gen KRAS2:presencia o identidad:punto en el tiempo:sangre entera/tejido:Nominal:genética molecular
es-ES	Spanish (Spain)	Gen KRAS Analisis de mutaciones:Presencia o identidad:Punto temporal:Sangre o tejido:Nom:Genética molecular
es-MX	Spanish (Mexico)	Análisis de mutaciones dirigidas al gen KRAS:Presencia o identidad:Punto temporal:Sangre o tejido:Nominal:Genética molecular
fr-FR	French (France)	KRAS gène mutation cible trouvée:Identification:Ponctuel:Sang/Tissu:Résultat nominal:Biologie moléculaire
it-IT	Italian (Italy)	KRAS, gene analisi di mutazione mirata:Prid:Pt:Sangue/Tess:Nom:Molgen Synonyms: Gene KRAS Genetica molecolare Mutazione genica Patologia molecolare Presenza o Identità Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci
ko-KR	Korean (Korea, Republic Of)	KRAS2 유전자 돌연변이 분석:존재:검사시점:전혈/조직:명칭결과:분자유전
nl-NL	Dutch (Netherlands)	KRAS-gen doelgerichte mutatie-analyse:identificator:moment:bloed of weefsel:nominaal:moleculair genetisch onderzoek Synonyms: KRAS gen molgen targeted
pl-PL	Polish (Poland)	KRAS gen ukierunkowana analiza mutacji:obecność lub identyfikacja:punkt w czasie:krew lub tkanka:skala nominalna:genetyka molekularna Synonyms: Analiza mutacji genu KRAS diagnostyka molekularna Gen KRAS wynik kategorialny
pt-BR	Portuguese (Brazil)	KRAS análise de mutação genética:Ident:Pt:Sg/Tecido:Nom:Genética molecular Synonyms: Kirsten rat sarcoma virus 2; RASK2; Oncogene KRAS2; V-KI-RAS1 pseudogene; KRAS1P; Oncogene KRAS1; Kirsten ras 1; RASK1; v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog; Identity or presence; Point in time; Random; Bld/T; Tissue; Bld/T; Blood; WB; Whole blood; Nominal; PCR; Molecular genetics; Mut Anal; Mutations; MOLPATH.MUTATIONS; MOLPATH.MUTATIONS; Molecular pathology
ru-RU	Russian (Russian Federation)	KRAS ген исследование на мутацию:ПрИд:ТчкВрм:Кр/Тк:Ном:МолГен Synonyms: Кровь Кровь или Ткань Номинальный;Именной Присутствие или Идентификация Ткань и мазки Точка во времени;Момент
tr-TR	Turkish (Turkey)	KRAS geni Mutasyon analizi:MevcKimlik:Zmlı:Kan/Dk:Snf:Molgen
uk-UA	Ukrainian (Ukraine)	ген KRAS аналіз мутації:Наявність або Ідентифікація:МоментЧасу:Кров/Тканини:Категорійно:Молекулярна генетика Synonyms: Blood; CFC2; C-K-RAS; Genetics; Heredity; Heritable; Identity or presence; Inherited; KI-RAS; Kirsten ras 1; Kirsten rat sarcoma viral oncogene homolog; Kirsten rat sarcoma virus 2; KRAS1; KRAS1P; KRAS2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; Molecular genetics; Molecular pathology; MOLPATH; MOLPATH.MUTATIONS; Mut; Mut Anl; Mutations; Nominal; NS; NS3; Oncogene KRAS1; Oncogene KRAS2; PCR; Point in time; Random; RASK1; RASK2; Tissue; Tissue, unspecified; V-KI-RAS1 pseudogene; v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog; WB; Whole blood; Whole blood or Tissue
zh-CN	Chinese (China)	KRAS2 基因突变分析:存在与否或特征标识:时间点:全血/组织:名义型:分子遗传学类实验室方法 Synonyms: Kirsten 大鼠肉瘤病毒 2;RASK1;RASK2;V-KI-RAS1 假基因;V-KI-RAS1 拟基因;v-Ki-ras2 Kirsten 大鼠肉瘤 2 病毒性癌基因同源基因;v-Ki-ras2 Kirsten 大鼠肉瘤 2 病毒性致癌基因同源基因;v-Ki-ras2 Kirsten 大鼠肉瘤 2 病毒癌基因同源基因;癌基因 KRAS1;癌基因 KRAS2;致癌基因 KRAS1;致癌基因 KRAS2 全血或组织;血液/组织;血液或组织分子病理学.基因突变;分子病理学.突变;分子病理学试验.基因突变;分子病理学试验.突变;分子病理学试验类.突变;基因突变;突变分子病理学;分子病理学试验分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答基因突变分析存在;存在与否;特征标识;身份;身份标识时刻;随机;随意;瞬间未作说明的组织;组织;组织 & 涂片血;血液遗传基因;遗传因子;吉恩;生物基因

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Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.