21720-8
NRAS gene mutations tested for in Blood or Tissue by Molecular genetics method Nominal
Active
Part Description
LP19749-8 NRAS gene
The NRAS gene (neuroblastoma RAS viral (v-ras) oncogene homolog) [HGNC Gene ID:7989] is located on chromosome 1p13.2. This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011] [NCBI Gene ID:4893]
Source: National Center for Biotechnology Information (NCBI) Gene
Fully-Specified Name
- Component
- NRAS gene mutations tested for
- Property
- Prid
- Time
- Pt
- System
- Bld/Tiss
- Scale
- Nom
- Method
- Molgen
Additional Names
- Short Name
- NRAS gene Mut Tested Bld/T
- Display Name
- NRAS gene mutations tested for Molgen Nom (Bld/Tiss)
- Consumer Name Alpha Get Info
- NRAS gene variants tested for, Blood or tissue specimen
Basic Attributes
- Class
- MOLPATH.MUT
- Type
- Laboratory
- First Released
- Version 1.0m
- Last Updated
- Version 2.13
- Order vs. Observation
- Observation
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-AR | Spanish (Argentina) | determinación de mutaciones del gen NRAS: |
es-ES | Spanish (Spain) | Gen NRAS Análisis de mutaciones para...: |
es-MX | Spanish (Mexico) | Mutaciones del gen NRAS analizadas para: |
fr-FR | French (France) | NRAS gène mutations recherchées: |
it-IT | Italian (Italy) | NRAS, gene, mutazioni testate per: Synonyms: Gene NRAS Genetica molecolare Mutazione genica Patologia molecolare Presenza o Identità Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & |
ko-KR | Korean (Korea, Republic Of) | NRAS 유전자 돌연변이 분석용: |
nl-NL | Dutch (Netherlands) | NRAS-gen geteste mutaties: Synonyms: molgen NRAS gen |
pt-BR | Portuguese (Brazil) | NRAS teste para mutação do gene: Synonyms: Oncogene NRAS; |
ru-RU | Russian (Russian Federation) | NRAS ген мутации тестирован на: Synonyms: Кровь Кровь или Ткань Номинальный; |
tr-TR | Turkish (Turkey) | NRAS geni mutasyonlar, test edilen: |
zh-CN | Chinese (China) | NRAS 基因 已测试的突变: Synonyms: v-ras 成神经细胞瘤 RAS 病毒癌基因同源基因; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
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