Version 2.77

Part Description

LP19774-6   CCND1 gene rearrangements
The CCND1 gene (cyclin D1) [HGNC Gene ID:1582] is located on chromosome 11q13. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq, Jul 2008] [NCBI Gene ID:595] Source: National Center for Biotechnology Information (NCBI) Gene

Fully-Specified Name

Component
CCND1 gene rearrangements
Property
Arb
Time
Pt
System
Bld/Tiss
Scale
Ord
Method
Molgen

Additional Names

Short Name
CCND1 gene Rear Bld/T Ql
Display Name
CCND1 rearrangements Molgen Ql (Bld/Tiss)
Consumer Name Alpha Get Info
CCND1 rearrangements, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.REARRANGE
Type
Laboratory
First Released
Version 1.0m
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
19327

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) reordenamientos del gen CCND1:arbitrario:punto en el tiempo:sangre entera/tejido:ordinal:genética molecular
es-ES Spanish (Spain) Reordenamientos del gen CCND1:Arbitrario:Punto temporal:Sangre o tejido:Ord:Genética molecular
es-MX Spanish (Mexico) Reordenamientos del gen CCND1:Arbitrario:Punto temporal:Sangre o tejido:Ordinal:Genética molecular
fr-FR French (France) CCND1 gène réarrangements:Arbitraire:Ponctuel:Sang/Tissu:Qualitatif:Biologie moléculaire
it-IT Italian (Italy) CCND1, riarrangiamenti gene:Arb:Pt:Sangue/Tess:Ord:Molgen
Synonyms: Arbitrario Gene CCND1 Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Riarrangiamenti gene CCND1 Riarrangiamento genico Sangue Sangue o Tessuto Tessuto & Strisci
ko-KR Korean (Korea, Republic Of) CCND1 유전자 재배열:임의적분:검사시점:전혈/조직:순위척도:분자유전
nl-NL Dutch (Netherlands) CCND1-genherschikking:aanwezigheid:moment:bloed of weefsel:ordinaal:moleculair genetisch onderzoek
Synonyms: CCND1 gen CCND1 gen translocaties molgen
pt-BR Portuguese (Brazil) CCND1 rearranjos do gene:Arb:Pt:Sg/Tecido:Ord:Genética molecular
Synonyms: ; CCND1 gene Rear; Lymphoma 1; B-cell CLL; BCL1; BCL-1; D11S287E; HGNC:988; PRAD1; U21B31; Cyclin D1; Parathyroid adenomatosis 1; Arbitrary; Point in time; Random; Bld/T; Tissue; Bld/T; Blood; WB; Whole blood; Ql; Ordinal; QL; Qualitative; Qual; Screen; PCR; Molecular genetics; Rearrang; Rearr; Rearrangement; MOLPATH.REARRANGEMENTS; MOLPATH.REARRANGEMENTS; Molecular pathology
ru-RU Russian (Russian Federation) CCND1 ген перестройки:Произв:ТчкВрм:Кр/Тк:Пор:МолГен
Synonyms: Кровь Кровь или Ткань Порядковый Произвольный Ткань и мазки Точка во времени;Момент
tr-TR Turkish (Turkey) CCND1 geni yeniden düzenlemeler:Sç:Zmlı:Kan/Dk:Srl:Molgen
zh-CN Chinese (China) CCND1 基因重排:任意型:时间点:全血/组织:序数型:分子遗传学类实验室方法
Synonyms: B 细胞 CLL;B 细胞慢性淋巴细胞白血病;BCL1;BCL-1;D11S287E;HGNC:988;PRAD1;U21B31;慢性 B 淋巴细胞白血病;淋巴瘤 1;甲状旁腺腺上皮增生症 1;甲状旁腺腺瘤病 1;细胞周期素 D1;细胞周期蛋白 D1 CCND1 基因重排（重组） 任意;任意的;人工型 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 全血或组织;血液/组织;血液或组织 分子病理学.基因重排;分子病理学.重排;分子病理学试验.基因重排;分子病理学试验.重排;分子病理学试验类.重排;基因重排;重排 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 血;血液 遗传基因;遗传因子;吉恩;生物基因

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