21746-3
BCL6 gene rearrangements [Presence] in Blood or Tissue by Molecular genetics method
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Part Descriptions
LP19776-1 BCL6 gene rearrangements
The protein encoded by the BCL6 gene arrangements is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
Source: National Center for Biotechnology Information (NCBI) Gene,
BCL6 gene rearrangements
LP19776-1 BCL6 gene rearrangements
The BCL6 gene (B-cell CLL/lymphoma 6) [HGNC Gene ID:1001] is located on chromosome 3q27. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2008] [NCBI Gene ID:604]
Source: National Center for Biotechnology Information (NCBI) Gene
LOINC Names Get Info
- Fully-Specified Name
- BCL6 gene rearrangements:
Arb: Pt: Bld/Tiss: Ord: Molgen - Long Common Name
- BCL6 gene rearrangements [Presence] in Blood or Tissue by Molecular genetics method
- Short Name
- BCL6 gene Rear Bld/T Ql
- Display Name
- BCL6 rearrangements Molgen Ql (Bld/Tiss)
- Consumer Name Alpha Get Info
- BCL6 rearrangements, Blood or tissue specimen
Part Model Get Info
Basic Attributes
- Class
- MOLPATH.REARRANGE
- Type
- Laboratory
- First Released
- Version 1.0m
- Last Updated
- Version 2.73 (MIN)
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 13110
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Gen BCL6 přestavba: |
| el-GR | Greek (Greece) | Γονιδιακές αναδιατάξεις BCL6: Synonyms: Arb BCL6 MOLPATH MOLPATH.REARRANGE Ord Pt Αίμα Αίμα/Ιστός Γονιδιακές αναδιατάξεις BCL6 Γονίδιο Ιστός Μοριακή γενετική |
| es-AR | Spanish (Argentina) | reordenamientos del gen BCL6: |
| es-ES | Spanish (Spain) | Reordenamientos del gen BCL6: |
| es-MX | Spanish (Mexico) | Reordenamientos del gen BCL6: |
| fr-FR | French (France) | BCL6 gène réarrangements: |
| it-IT | Italian (Italy) | BCL6, riarrangiamenti gene: Synonyms: Arbitrario Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Riarrangiamenti gene BCL6 Riarrangiamento genico Sangue Sangue o Tessuto Tessuto & |
| ko-KR | Korean (Korea, Republic Of) | BCL6 유전자 재배열: |
| nl-NL | Dutch (Netherlands) | BCL6-genherschikking: Synonyms: BCL6 gen translocaties molgen |
| pl-PL | Polish (Poland) | BCL6 gen rearanżacje: Synonyms: diagnostyka molekularna Rearanżacje genu BCL6 |
| pt-BR | Portuguese (Brazil) | BCL6 rearranjos do gene: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | BCL6 ген перестройки: Synonyms: Кровь Кровь или Ткань Порядковый Произвольный Ткань и мазки Точка во времени; |
| tr-TR | Turkish (Turkey) | BCL6 geni yeniden düzenlenmeler: |
| zh-CN | Chinese (China) | BCL6 基因重排: Synonyms: BCL6 基因重排(重组); |
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