Version 2.77

Part Description

LP19780-3   MYC gene rearrangements
The MYC gene (v-myc avian myelocytomatosis viral oncogene homolog) [HGNC Gene ID:7553] is located on chromosome 8q24.21. The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008] [NCBI Gene ID:4609] Source: National Center for Biotechnology Information (NCBI) Gene

Fully-Specified Name

Component
MYC gene rearrangements
Property
Arb
Time
Pt
System
Bld/Tiss
Scale
Ord
Method
Molgen

Additional Names

Short Name
MYC gene Rear Bld/T Ql
Display Name
MYC gene rearrangements Molgen Ql (Bld/Tiss)
Consumer Name Alpha Get Info
MYC gene rearrangements, Blood or tissue specimen

Basic Attributes

Class
MOLPATH.REARRANGE
Type
Laboratory
First Released
Version 1.0m
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
19400

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) reordenamientos del gen MYC:arbitrario:punto en el tiempo:sangre entera/tejido:ordinal:genética molecular
es-ES Spanish (Spain) Reordenamientos del gen MYC:Arbitrario:Punto temporal:Sangre o tejido:Ord:Genética molecular
es-MX Spanish (Mexico) Reordenamientos del gen MYC:Arbitrario:Punto temporal:Sangre o tejido:Ordinal:Genética molecular
fr-FR French (France) MYC gène réarrangements:Arbitraire:Ponctuel:Sang/Tissu:Qualitatif:Biologie moléculaire
it-IT Italian (Italy) MYC, riarrangiamenti gene:Arb:Pt:Sangue/Tess:Ord:Molgen
Synonyms: Arbitrario Gene MYC Genetica molecolare Patologia molecolare Punto nel tempo (episodio) Riarrangiamenti gene MYC Riarrangiamento genico Sangue Sangue o Tessuto Tessuto & Strisci
ko-KR Korean (Korea, Republic Of) MYC 유전자 재배열:임의적분:검사시점:전혈/조직:순위척도:분자유전
nl-NL Dutch (Netherlands) MYC genherschikking:aanwezigheid:moment:bloed of weefsel:ordinaal:moleculair genetisch onderzoek
Synonyms: molgen MYC gen MYC gentranslocatie
pt-BR Portuguese (Brazil) MYC rearranjos do gene:Arb:Pt:Sg/Tecido:Ord:Genética molecular
Synonyms: ; MYC gene Rear; Arbitrary; Point in time; Random; Bld/T; Tissue; Bld/T; Blood; WB; Whole blood; Ql; Ordinal; QL; Qualitative; Qual; Screen; PCR; Molecular genetics; Rearrang; Rearr; Rearrangement; Burkitt lymphoma; Protooncogene homologous to myelocytomatosis virus; Burkitts lymphoma; v-myc myelocytomatosis viral oncogene homolog; c-MYC; MOLPATH.REARRANGEMENTS; MOLPATH.REARRANGEMENTS; Molecular pathology
ru-RU Russian (Russian Federation) MYC ген перестройки:Произв:ТчкВрм:Кр/Тк:Пор:МолГен
Synonyms: Кровь Кровь или Ткань Порядковый Произвольный Ткань и мазки Точка во времени;Момент
tr-TR Turkish (Turkey) MYC geni yeniden düzenlemeler:Sç:Zmlı:Kan/Dk:Srl:Molgen
zh-CN Chinese (China) MYC 基因重排:任意型:时间点:全血/组织:序数型:分子遗传学类实验室方法
Synonyms: Burkitt 淋巴瘤 Burkitts 淋巴瘤 c-MYC MYC 原癌基因 MYC 基因重排(重组) v-myc myelocytomatosis viral oncogene homolog (avian);MYC;MRTL;bHLHe39;c-Myc;avian myelocytomatosis viral oncogene homolog;class E basic helix-loop-helix protein 39;myc proto-oncogene protein;myc-related translation/localization regulatory factor;proto-on v-myc 骨髓细胞瘤病毒原癌基因同源基因 v-myc 骨髓细胞瘤病毒原癌基因同源基因(v-myc myelocytomatosis viral oncogene homolog) v-myc 髓细胞瘤病毒原癌基因同源基因 v-myc 髓细胞组织增生病毒原癌基因同源基因 v-myc 髓细胞组织增生症病毒原癌基因同源基因 与骨髓细胞瘤病毒同源的原癌基因 与骨髓细胞瘤病毒同源的原癌基因(Protooncogene homologous to myelocytomatosis virus) 与髓细胞瘤病毒同源的原癌基因 与髓细胞组织增生病毒同源的原癌基因 与髓细胞组织增生症病毒同源的原癌基因 任意;任意的;人工型 伯基特氏淋巴瘤 伯基特淋巴瘤 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 全血或组织;血液/组织;血液或组织 分子病理学.基因重排;分子病理学.重排;分子病理学试验.基因重排;分子病理学试验.重排;分子病理学试验类.重排;基因重排;重排 分子病理学;分子病理学试验 分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内,用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 血;血液 遗传基因;遗传因子;吉恩;生物基因 骨髓细胞瘤病毒同源原癌基因 髓细胞瘤病毒同源原癌基因 髓细胞组织增生病毒同源原癌基因 髓细胞组织增生症病毒同源原癌基因

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