21810-7

t(14;18)(q32;q21.3)(IGH,BCL2) fusion transcript minor break points [Presence] in Blood or Tissue by Molecular genetics method

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Part Description

LP19837-1 t(14;18)(q32;q21.3)(IGH,BCL2)
Chromosomal translocation t(14;18)(q32;q21.3) IGH-BCL2 is found in follicular lymphomas (80-90%), diffuse large cell lymphomas (30%), and rarely in other lymphoproliferative disorders. It mainly occurs in B- cell non-hodgkin's lymphoma (NHL). This translocation is cytogenetically indistinguishable from t(14;18)(q32;q21) IGH-MALT1.[Atlas Genetics Oncology: t1418ID2006] FISH with probes specific to the targeted genes distinguishs between the two different rearrangements. Source: Regenstrief LOINC, t(14;18)(q32;q21) IGH/BCL2

LOINC Names Get Info

Fully-Specified Name: t(14;18)(q32;q21.3)(IGH,BCL2) fusion transcript minor break points:Arb:Pt:Bld/Tiss:Ord:Molgen
Long Common Name: t(14;18)(q32;q21.3)(IGH,BCL2) fusion transcript minor break points [Presence] in Blood or Tissue by Molecular genetics method
Short Name: t(14;18)(IGH,BCL2) Minor Bld/T Ql
Display Name: t(14;18)(q32;q21.3)(IGH,BCL2) fusion transcript minor break points Molgen Ql (Bld/Tiss)
Consumer Name Alpha Get Info: t(14;18)(q32;q21.3)(IGH,BCL2) minor break point analysis, Blood or tissue specimen

Part Model Get Info

Component
t(14;18)(q32;q21.3)(IGH,BCL2) fusion transcript minor break points
LP19839-7
- Analyte
  t(14;18)(q32;q21.3)(IGH,BCL2) fusion transcript minor break points
  LP19839-7
  - Component Numerator
    t(14;18)(q32;q21.3)(IGH,BCL2) fusion transcript minor break points
    LP19839-7
    - Component Numerator Core
      t(14;18)(q32;q21.3)(IGH,BCL2)
      LP19837-1
    - Component Numerator Core Suffix
      fusion transcript minor break points
      LP150245-1
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Arb
LP6781-1
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Bld/Tiss
LP7061-7
- System Core
  Bld/Tiss
  LP7061-7
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Molgen
LP6404-0

Basic Attributes

Class: MOLPATH.TRNLOC
Type: Laboratory
First Released: Version 1.0m
Last Updated: Version 2.50 (MIN)
Change Reason: Updated Component part to harmonize with ISCN guidelines and current LOINC nomenclature.
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Fúzní transkript t(14;18)(q32;q21.3)(IGH,BCL2) drobné body zlomu:Arbitrární:Časový bod:Krev/tkáň:Ordinální:Molekulární genetika
el-GR	Greek (Greece)	t(14;18)(q32;q21.3)(IGH,BCL2) ελάσσονα σημεία διακοπής μεταγραφών συγχώνευσης:Arb:Pt:Αίμα/Ιστός:Ord:Μοριακή γενετική Synonyms: Arb BCL2 MOLPATH MOLPATH.TRNLOC Ord Pt t(14;18)(q32;q21.3)(IGH,BCL2) Αίμα Αίμα/Ιστός ελάσσονα σημεία διακοπής μεταγραφών συγχώνευσης Ιστός μεταγραφή συγχώνευσης Μοριακή γενετική
es-AR	Spanish (Argentina)	puntos de rupturas menores de translocación del gen T(14,18)(IGH,BCL2):arbitrario:punto en el tiempo:sangre entera/tejido:ordinal:genética molecular
es-ES	Spanish (Spain)	t(14;18)(q32;q21.3)(IGH,BCL2) punto de rotura menor del transcrito de fusion:Arbitrario:Punto temporal:Sangre o tejido:Ord:Genética molecular
es-MX	Spanish (Mexico)	t (14; 18) (q32; q21.3) (IGH, BCL2) puntos de ruptura menores de la transcripción de fusión:Arbitrario:Punto temporal:Sangre o tejido:Ordinal:Genética molecular
fr-FR	French (France)	t(14;18)(q32;q21.3)(IGH,BCL2) transcrit de fusion point de rupture mineur:Arbitraire:Ponctuel:Sang/Tissu:Qualitatif:Biologie moléculaire
it-IT	Italian (Italy)	t(14,18)(q32,q21.3)(IGH,BCL2), punti di rottura secondari di trascritto di fusione:Arb:Pt:Sangue/Tess:Ord:Molgen Synonyms: Arbitrario Genetica molecolare Patologia molecolare Punti di rottura minori della traslocazione t(14,18)(IGH,BCL2) Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci Traslocazione genetica
ko-KR	Korean (Korea, Republic Of)	t(14,18)(IGH,BCL2) 유전자 전위 부변 곡점:임의적분:검사시점:전혈/조직:순위척도:분자유전
nl-NL	Dutch (Netherlands)	t(14;18)(q32;q21.3)(IGH,BCL2) fusietranscript minor breakpoints:aanwezigheid:moment:bloed of weefsel:ordinaal:moleculair genetisch onderzoek Synonyms: molgen
pl-PL	Polish (Poland)	t (14; 18) (q32; q21.3) (IGH,BCL2) mniejsze punkty przerwania transkryptu fuzyjnego:jednostka umowna:punkt w czasie:krew lub tkanka:uporządkowany:genetyka molekularna Synonyms: diagnostyka molekularna Translokacja (14; 18) (q32; q21.3) (IGH,BCL2) Translokacja (14; 18) (q32; q21.3) (IGH,BCL2) mniejsze punkty przerwania transkryptu genu fuzyjnego Translokacja(14; 18) (q32; q21.3) (IGH,BCL2) transkrypt genu fuzyjnego
pt-BR	Portuguese (Brazil)	t(14,18)(IGH,BCL2) translocação do gene menor ponto de quebra:Arb:Pt:Sg/Tecido:Ord:Genética molecular Synonyms: ; t(14,18)(IGH,BCL2)Min; BCL-2; B-cell leukemia/lymphoma 2; Arbitrary; Point in time; Random; Bld/T; Tissue; Bld/T; Blood; WB; Whole blood; Ql; Ordinal; QL; Qualitative; Qual; Screen; PCR; Molecular genetics; Follicular B cell lymphoma; t(14,18)(q32,q21); Oncogene B-cell leukemia 2; CLL; Chronic lymphatic leukemia; Follicular lymphoma; Non-Hodgkin lymphoma; T prime; Mcr; Minor Cluster Region; MOLPATH.TRANSLOCATION; MOLPATH.TRANSLOCATION; Molecular pathology
ru-RU	Russian (Russian Federation)	t(14;18)(q32;q21.3)(IGH,BCL2) слияния транскрипт minor break points:Произв:ТчкВрм:Кр/Тк:Пор:МолГен Synonyms: Кровь Кровь или Ткань Порядковый Произвольный слияния транскрипт минорная точка разрыва Ткань и мазки Точка во времени;Момент химерная РНК, закодированная слитым геном
tr-TR	Turkish (Turkey)	t(14;18)(q32;q21.3)(IGH,BCL2) füzyon transkript minor kırılma noktaları:Sç:Zmlı:Kan/Dk:Srl:Molgen
zh-CN	Chinese (China)	t(14;18)(q32;q21.3)(IGH,BCL2) 融合转录物次要断裂点:任意型:时间点:全血/组织:序数型:分子遗传学类实验室方法 Synonyms: BCL-2;B-细胞白血病/淋巴瘤 2;B细胞白血病/淋巴瘤2 MCR T(14,18)(IGH,BCL2) 基因易位;T(14,18)(IGH,BCL2) 易位 T(14,18)(IGH,BCL2) 基因易位次要断裂点任意;任意的;人工型依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型全血或组织;血液/组织;血液或组织分子病理学.基因易位;分子病理学.易位;分子病理学试验.基因易位;分子病理学试验.易位;分子病理学试验类.易位;基因易位分子病理学;分子病理学试验分子遗传学;分子遗传学方法;分子遗传学类方法;分子遗传学类检验方法;包括 RFL、PCR 及其他方法在内，用于在分子基础上检测遗传属性的方法的大类;聚合酶链反应;聚合酶链式反应时刻;随机;随意;瞬间未作说明的组织;组织;组织 & 涂片次断点次断点类次断裂点类次要丛集区次要丛集区域次要断点次要断点类次要断裂点次要断裂点类次要簇集区次要簇集区域次要集中区次要集中区（Minor Cluster Region，MCR）次要集中区域融合转录物（转录本、转录产物、转录子、转录）;融合基因转录本;融合转录融合转录物（转录本、转录产物、转录子、转录）次要断裂点;融合基因转录本次要断裂点;融合转录本次要断点血;血液

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Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.