2280-6
Fibronectin [Mass/volume] in Plasma
Active
Term Description
I found this measured on ascitic fluid
Part Description
LP15573-6 Fibronectin
Fibronectin is a high-molecular weight (~440kDa) extracellular matrix glycoprotein that binds to membrane-spanning receptor proteins called integrins. In addition to integrins, fibronectin also binds extracellular matrix components such as collagen, fibrin and heparan sulfate proteoglycans (e.g. syndecans).
Fibronectin exists as a dimer, consisting of two nearly identical monomers linked by a pair of disulfide bonds. The fibronectin protein is produced from a single gene, but alternative splicing of its pre-mRNA leads to the creation of several isoforms.
Two types of fibronectin are present in vertebrates:
- soluble plasma fibronectin (formerly called "cold-insoluble globulin", or CIg) is a major protein component of blood plasma (300 μg/ml) and is produced in the liver by hepatocytes.
- insoluble cellular fibronectin is a major component of the extracellular matrix. It is secreted by various cells, primarily fibroblasts, as a soluble dimer and is then assembled into an insoluble matrix in a complex cell-mediated process.
Fibronectin plays a major role in cell adhesion, growth, migration and differentiation, and it is important for processes such as wound healing and embryonic development. Altered fibronectin expression, degradation, and organization has been associated with a number of pathologies, including cancer and fibrosis.
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Source: Wikipedia,
Wikipedia
LOINC Names Get Info
- Fully-Specified Name
- Fibronectin:
MCnc: Pt: Plas: Qn: - Long Common Name
- Fibronectin [Mass/volume] in Plasma
- Short Name
- Fibronectin Plas-mCnc
- Display Name
- Fibronectin (P) [Mass/Vol]
- Consumer Name Alpha Get Info
- Fibronectin, Blood
Part Model Get Info
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.42 (MIN)
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Fibronektin: |
| de-AT | German (Austria) | Synonyms: Fibronectin |
| de-DE | German (Germany) | Fibronektin: |
| el-GR | Greek (Greece) | Φιμπρονεκτίνη: Synonyms: CHEM MCnc Pt Qn Πλάσμα Φιμπρονεκτίνη |
| es-AR | Spanish (Argentina) | fibronectina: |
| es-MX | Spanish (Mexico) | Fibronectina: |
| es-ES | Spanish (Spain) | Fibronectina: Synonyms: Cuantitativo |
| et-EE | Estonian (Estonia) | Fibronektiin: Synonyms: Juhuslik Kvantitatiivne Plasma |
| fr-CA | French (Canada) | Fibronectine: |
| fr-FR | French (France) | Fibronectine: |
| fr-BE | French (Belgium) | Fibronectine: |
| it-IT | Italian (Italy) | Fibronectina: Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) |
| ko-KR | Korean (Korea, Republic Of) | 섬유결합소: |
| nl-NL | Dutch (Netherlands) | fibronectine: |
| pt-BR | Portuguese (Brazil) | Fibronectina: Synonyms: FN; |
| ru-RU | Russian (Russian Federation) | Фибронектин: Synonyms: Количественный Массовая концентрация Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Fibronektin: |
| zh-CN | Chinese (China) | 纤维连接蛋白: Synonyms: FN; |
Example Units
| Unit | Source |
|---|---|
| ug/mL | Example UCUM Units |
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