22984-9

Capripox virus neutralizing antibody [Presence] in Serum by Neutralization test

Active

Part Descriptions

LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Capripox virus Ab.Neut:PrThr:Pt:Ser:Ord:Neut
Long Common Name: Capripox virus neutralizing antibody [Presence] in Serum by Neutralization test
Short Name: Capripox NAb Ser Ql Nt
Display Name: Capripox virus neut ab Neut test Ql (S)
Consumer Name Alpha Get Info: Capripox virus neutralizing antibody, Blood

Part Model Get Info

Component
Capripox virus Ab.Neut
LP430333-7
- Analyte
  Capripox virus Ab.Neut
  LP430333-7
  - Component Numerator
    Capripox virus Ab.Neut
    LP430333-7
    - Component Numerator Core
      Capripox virus
      LP19883-5
    - Component Numerator Core Suffix
      Ab.Neut
      LP207365-0
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Neut
LP6416-4

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 1.0n
Last Updated: Version 2.72 (NAM)
Change Reason: Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.; Previous Releases: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Capripoxvirus Ab.neutralizační:Přítomnost nebo práh:Časový bod:Sérum:Ordinální:Neutralizační test
el-GR	Greek (Greece)	Ιός της ευλογίας των αιγοπροβάτων Ab.Neut:PrThr:Pt:Ορός:Ord:Ουδετερόφιλα Synonyms: Ab.Neut MICRO Ord PrThr Pt Αντίσωμα Ιός Ιός της ευλογίας των αιγοπροβάτων Ορός Ουδετερόφιλα
es-AR	Spanish (Argentina)	anticuerpo contra el virus de la viruela caprina:concentración arbitraria:punto en el tiempo:suero:ordinal:neutralización
es-ES	Spanish (Spain)	Virus Capripox Anticuerpos antineutrófilos:PrThr:Punto temporal:Suero:Ord:Prueba de neutralización
es-MX	Spanish (Mexico)	Virus Capripox Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Prueba de neutralización
fr-CA	French (Canada)	Capripoxvirus Ac.neut:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Test de neutralisation
it-IT	Italian (Italy)	Capripox virus Ab.Neut:PrThr:Pt:Siero:Ord:Neut Synonyms: anticorpo Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero Test di neutralizzazione
ko-KR	Korean (Korea, Republic Of)	카프리폭스 바이러스 항체:임의농도:검사시점:혈청:순위척도:중화
nl-NL	Dutch (Netherlands)	Capripoxvirus As.neutraliserend:aanwezigheid:moment:serum:ordinaal:neutralisatietest Synonyms: antistof; antilichaam
pl-PL	Polish (Poland)	Kozi wirus ospy Ab.Neutralizujące:granica wykrywalności:punkt w czasie:surowica:uporządkowany:test neutralizacji Synonyms: Kosi wirus ospy Przeciwciała do koziego wirusa ospy Przeciwciała neutralizujace do koziego wirusa ospy
pt-BR	Portuguese (Brazil)	Capripox vírus Ac:ACnc:Pt:Soro:Ord:Teste de neutralização Synonyms: Sheep pox; Goat pox; Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; Nt; NT; Neutralization test; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
zh-CN	Chinese (China)	山羊痘病毒抗体.中和:存在情况或阈值:时间点:血清:序数型:中和试验 Synonyms: Ab;自身抗体中和试验;中和抗体;中和传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）山羊痘;绵羊痘;羊痘山羊痘病毒 Ab 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）时刻;随机;随意;瞬间

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.