Version 2.78

Part Descriptions

LP14238-7   Eastern equine encephalitis virus
Eastern equine encephalitis virus (EEEV), commonly called sleeping sickness or Triple E, is a zoonotic alphavirus and arbovirus present in North, Central and South America and the Caribbean. EEEV was first recognised in Massachusetts, USA in 1831 when 75 horses died of encephalitic illness. Epizootics in horses have continued to occur regularly in USA. The causal agent, EEEV, was first isolated from infected horse brains in 1933. In 1938, the first confirmed human cases were identified when thirty children died of encephalitis in northeastern USA. These cases coincided with outbreaks in horses in the same regions. The fatality rate in humans infected with EEEV is 35%. EEEV is capable of infecting a wide range of animals including mammals, birds, reptiles and amphibians, but not all animals develop high enough levels of EEEV to be contagious to humans. The virus is maintained in birds primarily through Culiseta melanura mosquitoes and transmission to other species occurs via mosquitoes. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Eastern equine encephalitis virus (Wikipedia)

LP14238-7   Eastern equine encephalitis virus
Eastern equine encephalitis is an encephalitogenic arbovirus common in North America and transmitted to humans via an arthropod vector. Central nervous system infection may present as aseptic meningitis, encephalitis, or meningoencephalitis. Information from ARUP Laboratories and Jacobs and DeMott Laboratory Test Handbook, 5th edition, DS Jacobs, WR DeMott and DK Oxley, 2001. Source: Regenstrief Institute

LP207365-0   Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP6416-4   Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

Fully-Specified Name

Component
Eastern equine encephalitis virus Ab.Neut
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
Neut

Additional Names

Short Name
EEEV NAb Ser Ql Nt
Display Name
EEEV neut ab Neut test Ql (S)
Consumer Name Alpha Get Info
Eastern equine encephalitis virus neutralizing antibody, Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 1.0n
Last Updated
Version 2.72
Change Reason
Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.; Previous Releases: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG32751-6 Eastern equine encephalitis virus

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) [anticuerpo anti - ] virus de la encefalitis equina del este [Ac]:concentración arbitraria:punto en el tiempo:suero:ordinal:neutralización
es-ES Spanish (Spain) Virus de la Encefalitis Equina del este Anticuerpos antineutrófilos:PrThr:Punto temporal:Suero:Ord:Prueba de neutralización
es-MX Spanish (Mexico) Virus de la encefalitis equina del este Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Prueba de neutralización
fr-CA French (Canada) Virus de l'encéphalite équine de l'Est Ac.neut:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Test de neutralisation
it-IT Italian (Italy) Encefalite equina orientale virus Ab.Neut:PrThr:Pt:Siero:Ord:Neut
Synonyms: anticorpo Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero Test di neutralizzazione Virus dell''encefalite equina orientale
ko-KR Korean (Korea, Republic Of) 동부 말 뇌염 바이러스 항체:임의농도:검사시점:혈청:순위척도:중화
nl-NL Dutch (Netherlands) Oosters equien encefalitisvirus As.neutraliserend:aanwezigheid:moment:serum:ordinaal:neutralisatietest
Synonyms: antistof; antilichaam Oosters paardenencefalitisvirus
pl-PL Polish (Poland) Wirus wschodniego końskiego zapalenia mózgu Ab.Neutralizujące:granica wykrywalności:punkt w czasie:surowica:półilościowy:test neutralizacji
Synonyms: Przeciwciała do wirusa wschodniego końskiego zapalenia mózgu Przeciwciała neutralizujące do wirusa wschodniego końskiego zapalenia mózgu Wirus wschodniego końskiego zapalenia mózgu
pt-BR Portuguese (Brazil) Encefalite equina oriental vírus Ac:ACnc:Pt:Soro:Ord:Teste de neutralização
Synonyms: ; EEEV; Togavirus; EEE virus; Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; Nt; NT; Neutralization test; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Equin; Enceph; Enc; Encephalomyelitis; Microbiology
zh-CN Chinese (China) 东方马脑炎病毒 抗体.中和:存在情况或阈值:时间点:血清:序数型:中和试验
Synonyms: Ab;自身抗体 EEE 病毒 Ab EEE 病毒;EEEV;囊膜病毒;外衣病毒;东部型马脑炎病毒;东方型马脑炎病毒 EEE 病毒抗体 EEEV Ab EEEV 抗体 东方马脑炎病毒 Ab 中和试验;中和抗体;中和 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 似马的 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 大脑炎 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 脑炎（Encephalitis，大脑炎） 脑脊髓炎 脑脊髓炎（Encephalomyelitis） 马的 马科 马科动物 马科的

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=23044-1