23107-6
Foot and mouth disease virus neutralizing antibody [Presence] in Serum by Neutralization test
Active
Part Descriptions
LP19897-5 Foot and mouth disease virus
Foot-and-mouth disease (FMD, Latin name Aphtae epizooticae), sometimes called hoof-and-mouth disease, is a highly contagious and sometimes fatal viral disease of cattle and pigs. It can also infect deer, goats, sheep, and other animals with cloven hooves, as well as elephants, rats, and hedgehogs. Horses are not susceptible to FMD. Humans are affected only very rarely. The cause of FMD was first shown to be viral in 1897 by Friedrich Loeffler. He passed the blood of an infected animal through a fine porcelain-glass filter and found that the fluid that was collected could still cause the disease in healthy animals.
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Source: Wikipedia,
Foot and mouth disease virus (Wikipedia)
LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method.
Source: Regenstrief LOINC
LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Foot and mouth disease virus Ab.Neut:
PrThr: Pt: Ser: Ord: Neut - Long Common Name
- Foot and mouth disease virus neutralizing antibody [Presence] in Serum by Neutralization test
- Short Name
- FMDV NAb Ser Ql Nt
- Display Name
- Foot and mouth disease virus neut ab Neut test Ql (S)
- Consumer Name Alpha Get Info
- Foot and Mouth Disease virus neutralizing antibody, Blood
Part Model Get Info
- Component
- Foot and mouth disease virus Ab.Neut
LP430396-4
- Analyte
- Foot and mouth disease virus Ab.Neut
LP430396-4
- Component Numerator
- Foot and mouth disease virus Ab.Neut
LP430396-4
- Component Numerator Core
- Foot and mouth disease virus
LP19897-5
- Component Numerator Core Suffix
- Ab.Neut
LP207365-0
- Component Denominator
- NULL
- Component Denominator Core
- NULL
- Component Denominator Core Suffix
- NULL
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- PrThr
LP217195-9
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- Ser
LP7567-3
- System Core
- Ser
LP7567-3
- Super System
- NULL
- Scale
- Ord
LP7751-3
- Method
- Neut
LP6416-4
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 1.0n
- Last Updated
- Version 2.72 (NAM)
- Change Reason
- Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.; Previous Releases: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Virus slintavky a kulhavky Ab.neutralizační: |
| el-GR | Greek (Greece) | Ιός αφθώδους πυρετού Ab.Neut: Synonyms: Ab.Neut MICRO Ord PrThr Pt Αντίσωμα Ιός Ιός αφθώδους πυρετού Ορός Ουδετερόφιλα |
| es-AR | Spanish (Argentina) | [anticuerpo anti - ] virus de la glosopeda [Ac]: |
| es-ES | Spanish (Spain) | Virus de la enfermedad pie y boca Anticuerpos antineutrófilos: |
| es-MX | Spanish (Mexico) | Virus de la fiebre aftosa Ab: |
| fr-FR | French (France) | Maladie pied main bouche virus Ac neutralisant: |
| fr-CA | French (Canada) | Aphthovirus Ac.neut: |
| it-IT | Italian (Italy) | Afta epizootica, virus Ab.Neut: Synonyms: anticorpo Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero Test di neutralizzazione Virus dell''afta epizootica |
| ko-KR | Korean (Korea, Republic Of) | 발입병 바이러스 항체: |
| nl-NL | Dutch (Netherlands) | Mond-en-klauwzeervirus As.neutraliserend: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Wirus pryszczycy Ab.Neutralizujące: Synonyms: Przeciwciała do wirusa pryszczycy Przeciwciała neutralizujące do wirusa pryszczycy Wirus pryszczycy |
| pt-BR | Portuguese (Brazil) | Febre aftosa vírus Ac: Synonyms: ; |
| zh-CN | Chinese (China) | 口蹄疫病毒 抗体.中和: Synonyms: Ab; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://