23562-2

Vesicular stomatitis Indiana virus neutralizing antibody [Presence] in Serum by Neutralization test

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Part Descriptions

LP14290-8 Vesicular stomatitis Indiana virus
Vesicular stomatitis Indiana virus (VSIV, formerly Indiana 1) and Vesicular stomatitis New Jersey virus (VSNJV) are members of the Vesiculovirus genera of the Rhabdovirus family. They are primarily zoonotic viruses that affect cattle, horses and pigs. Natural VSIV infections encompass two steps, cytolytic infections of mammalian hosts and transmission by insects. The genome is a single molecule of negative-sense RNA that encodes five major proteins: glycoprotein (G), matrix protein (M), nucleoprotein, large protein (L) and phosphoprotein. Half the genome encodes the L protein, which combines with the phosphoprotein to catalyze replication of the mRNA. Other members of the Vesiculovirus genera include Cocal virus (formerly Indiana 2) and Vesicular stomatitis Alagoas virus (formerly Indiana 3). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Vesicular stomatitis virus Indiana (Wikipedia)

LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Vesicular stomatitis Indiana virus Ab.Neut:PrThr:Pt:Ser:Ord:Neut
Long Common Name: Vesicular stomatitis Indiana virus neutralizing antibody [Presence] in Serum by Neutralization test
Short Name: VSIV NAb Ser Ql Nt
Display Name: Vesicular stomatitis Indiana virus neut ab Neut test Ql (S)
Consumer Name Alpha Get Info: Vesicular Stomatitis Indiana virus neutralizing antibody, Blood

Part Model Get Info

Component
Vesicular stomatitis Indiana virus Ab.Neut
LP430483-0
- Analyte
  Vesicular stomatitis Indiana virus Ab.Neut
  LP430483-0
  - Component Numerator
    Vesicular stomatitis Indiana virus Ab.Neut
    LP430483-0
    - Component Numerator Core
      Vesicular stomatitis Indiana virus
      LP14290-8
    - Component Numerator Core Suffix
      Ab.Neut
      LP207365-0
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Neut
LP6416-4

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 1.0n
Last Updated: Version 2.72 (NAM)
Change Reason: Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.; Previous Releases: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Virus vezikulární stomatitidy Indiana Ab.neutralizační:Přítomnost nebo práh:Časový bod:Sérum:Ordinální:Neutralizační test
el-GR	Greek (Greece)	Ιός φυσαλιδώδους στοματίτιδας ορότυπος Indiana Ab.Neut:PrThr:Pt:Ορός:Ord:Ουδετερόφιλα Synonyms: Ab.Neut MICRO Ord PrThr Pt Αντίσωμα Ιός Ιός φυσαλιδώδους στοματίτιδας ορότυπος Indiana Ορός Ουδετερόφιλα
es-AR	Spanish (Argentina)	[anticuerpo anti - ] virus Indiana de la estomatitis vesicular [Ac]:concentración arbitraria:punto en el tiempo:suero:ordinal:neutralización
es-ES	Spanish (Spain)	Virus de la estomatitis vesicular de Indiana Anticuerpos antineutrófilos:PrThr:Punto temporal:Suero:Ord:Prueba de neutralización
es-MX	Spanish (Mexico)	Estomatitis vesicular Indiana virus Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Prueba de neutralización
fr-FR	French (France)	Stomatite vésiculeuse type Indiana virus Ac neutralisant:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Neutralisation
fr-CA	French (Canada)	Virus de la stomatite vésiculaire, type Indiana Ac.neut:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Test de neutralisation
it-IT	Italian (Italy)	Stomatite vescicolare, virus Indiana Ab.Neut:PrThr:Pt:Siero:Ord:Neut Synonyms: anticorpo Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero Test di neutralizzazione Virus della stomatite vescicolare Indiana
ko-KR	Korean (Korea, Republic Of)	수포성 구내염 바이러스 인디애나 항체:임의농도:검사시점:혈청:순위척도:중화
nl-NL	Dutch (Netherlands)	vesiculaire stomatitis Indiana virus As.neutraliserend:aanwezigheid:moment:serum:ordinaal:neutralisatietest Synonyms: antistof; antilichaam
pl-PL	Polish (Poland)	Wirus pęcherzykowatego zapalenia jamy ustnej typ Indiana Ab.Neutralizujące:granica wykrywalności:punkt w czasie:surowica:uporządkowany:test neutralizacji Synonyms: Przeciwciała do wirusa pęcherzykowatego zapelnia jamy ustnej typu Indiana Przeciwciała neutralizujące do wirusa pęcherzykowatego zapelnia jamy ustnej typu Indiana
pt-BR	Portuguese (Brazil)	Estomatite vesicular vírus Indiana Ac:ACnc:Pt:Soro:Ord:Teste de neutralização Synonyms: ; VSIV; VS; VSV; RhAcdovirus; Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; Nt; NT; Neutralization test; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
zh-CN	Chinese (China)	水泡性口炎病毒 Indiana 型抗体.中和:存在情况或阈值:时间点:血清:序数型:中和试验 Synonyms: Ab;自身抗体 VS;VSIV;水泡性口炎病毒印地安纳型;印地安纳型水泡性口炎病毒 VSIV Ab VSIV 抗体中和试验;中和抗体;中和传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）时刻;随机;随意;瞬间水泡性口炎病毒 Indiana 型 Ab 水泡性口炎病毒印地安纳型 Ab 水泡性口炎病毒印地安纳型抗体

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.