23789-1
Vesicular stomatitis Indiana virus neutralizing antibody [Titer] in Serum by Neutralization test
Active
Part Descriptions
LP14290-8 Vesicular stomatitis Indiana virus
Vesicular stomatitis Indiana virus (VSIV, formerly Indiana 1) and Vesicular stomatitis New Jersey virus (VSNJV) are members of the Vesiculovirus genera of the Rhabdovirus family. They are primarily zoonotic viruses that affect cattle, horses and pigs. Natural VSIV infections encompass two steps, cytolytic infections of mammalian hosts and transmission by insects. The genome is a single molecule of negative-sense RNA that encodes five major proteins: glycoprotein (G), matrix protein (M), nucleoprotein, large protein (L) and phosphoprotein. Half the genome encodes the L protein, which combines with the phosphoprotein to catalyze replication of the mRNA. Other members of the Vesiculovirus genera include Cocal virus (formerly Indiana 2) and Vesicular stomatitis Alagoas virus (formerly Indiana 3).
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Source: Wikipedia,
Vesicular stomatitis virus Indiana (Wikipedia)
LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method.
Source: Regenstrief LOINC
LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Vesicular stomatitis Indiana virus Ab.Neut:
Titr: Pt: Ser: SemiQn: Neut - Long Common Name
- Vesicular stomatitis Indiana virus neutralizing antibody [Titer] in Serum by Neutralization test
- Short Name
- VSIV NAb Titr Ser Nt
- Display Name
- Vesicular stomatitis Indiana virus neut ab Neut test (S) [Titer]
- Consumer Name Alpha Get Info
- Vesicular Stomatitis Indiana virus neutralizing antibody, Blood
Part Model Get Info
- Component
- Vesicular stomatitis Indiana virus Ab.Neut
LP430483-0
- Analyte
- Vesicular stomatitis Indiana virus Ab.Neut
LP430483-0
- Component Numerator
- Vesicular stomatitis Indiana virus Ab.Neut
LP430483-0
- Component Numerator Core
- Vesicular stomatitis Indiana virus
LP14290-8
- Component Numerator Core Suffix
- Ab.Neut
LP207365-0
- Component Denominator
- NULL
- Component Denominator Core
- NULL
- Component Denominator Core Suffix
- NULL
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- Titr
LP6881-9
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- Ser
LP7567-3
- System Core
- Ser
LP7567-3
- Super System
- NULL
- Scale
- SemiQn
LP436123-6
- Method
- Neut
LP6416-4
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 1.0n
- Last Updated
- Version 2.75 (MAJ)
- Change Reason
- Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.;
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Virus vezikulární stomatitidy Indiana Ab.neutralizační: |
| el-GR | Greek (Greece) | Ιός φυσαλιδώδους στοματίτιδας ορότυπος Indiana Ab.Neut: Synonyms: Ab.Neut MICRO Pt Titr Αντίσωμα Ημιποσοτική Ιός Ιός φυσαλιδώδους στοματίτιδας ορότυπος Indiana Ορός Ουδετερόφιλα |
| es-AR | Spanish (Argentina) | [anticuerpo anti - ] virus Indiana de la estomatitis vesicular [Ac]: |
| es-ES | Spanish (Spain) | Virus de la estomatitis vesicular de Indiana Anticuerpos antineutrófilos: Synonyms: Semicuantitativo |
| es-MX | Spanish (Mexico) | Estomatitis vesicular Indiana virus Ab: |
| fr-FR | French (France) | Stomatite vésiculeuse type Indiana virus Ac neutralisant: |
| fr-CA | French (Canada) | Virus de la stomatite vésiculaire, type Indiana Ac.neut: |
| it-IT | Italian (Italy) | Stomatite vescicolare, virus Indiana Ab.Neut: Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Siero Test di neutralizzazione Titolo Virus della stomatite vescicolare Indiana |
| ko-KR | Korean (Korea, Republic Of) | 수포성 구내염 바이러스 인디애나 항체: |
| nl-NL | Dutch (Netherlands) | vesiculaire stomatitis Indiana virus As.neutraliserend: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Wirus pęcherzykowatego zapalenia jamy ustnej typ Indiana Ab.Neutralizujące: Synonyms: Przeciwciała do wirusa pęcherzykowatego zapelnia jamy ustnej typu Indiana Przeciwciała neutralizujące do wirusa pęcherzykowatego zapelnia jamy ustnej typu Indiana |
| pt-BR | Portuguese (Brazil) | Estomatite vesicular vírus Indiana Ac: Synonyms: ; |
| zh-CN | Chinese (China) | 水泡性口炎病毒 Indiana 型 抗体.中和: Synonyms: Ab; |
Example Units
| Unit | Source |
|---|---|
| {titer} | Example UCUM Units |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://