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Part Description

LP19423-0   Cytokeratin 19
Keratin, type I cytoskeletal 19 also known as cytokeratin-19 (CK-19) or keratin-19 (K19) is a protein that in humans is encoded by the KRT19 gene.

Due to its high sensitivity, KRT19 is the most used marker for the RT-PCR-mediated detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients. Depending on the assays, KRT19 has been shown to be both a specific and a non-specific marker. False positivity in such KRT19 RT-PCR studies include: illegitimate transcription (expression of small amounts of KRT19 mRNA by tissues in which it has no real physiological role), haematological disorders (KRT19 induction in peripheral blood cells by cytokines and growth factors, which circulate at higher concentrations in inflammatory conditions and neutropenia), the presence of pseudogenes (two KRT19 pseudogenes, KRT19a and KRT19b, have been identified, which have significant sequence homology to KRT19 mRNA. Subsequently, attempts to detect the expression of the authentic KRT19 may result in the detection of either or both of these pseudogenes), sample contamination (introduction of contaminating epithelial cells during peripheral blood sampling for subsequent RT-PCR analysis).

Keratin 19 is often used together with keratin 8 and keratin 18 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LOINC Names Get Info

Fully-Specified Name
Cytokeratin 19:MCnc:Pt:Ser/Plas:Qn:
Long Common Name
Cytokeratin 19 [Mass/volume] in Serum or Plasma
Short Name
CK 19 SerPl-mCnc
Display Name
Cytokeratin 19 [Mass/Vol]
Consumer Name Alpha Get Info
Cytokeratin 19, Blood

Part Model Get Info

  • Component
    Cytokeratin 19
    LP19423-0
    • Analyte
      Cytokeratin 19
      LP19423-0
      • Component Numerator
        Cytokeratin 19
        LP19423-0
        • Component Numerator Core
          Cytokeratin 19
          LP19423-0
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    MCnc
    LP6827-2
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.00
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Both
Common Test Rank Get Info
19516

Language Variants Get Info

TagLanguageTranslation
ar-JOArabic (Jordan)السيتوكيراتين 19 ( بتقنية الكتلة / الحجم ) في المصل أو البلازما
cs-CZCzech (Czechia)Cytokeratin 19:Hmotnostní koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
de-ATGerman (Austria)Synonyms: CYFRA 21-1
de-DEGerman (Germany)Zytokeratin 19:Massenkonzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:
Synonyms: Cyfra 21-1
el-GRGreek (Greece)Κυτοκερατίνη 19:MCnc:Pt:Ορός/Πλάσμα:Qn:
Synonyms: CHEM MCnc Pt Qn Κυτοκερατίνη 19 Ορός Ορός/Πλάσμα Πλάσμα
es-ARSpanish (Argentina)citoqueratina 19:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-MXSpanish (Mexico)Citoqueratina 19:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
es-ESSpanish (Spain)Citoqueratina 19:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
et-EEEstonian (Estonia)Tsütokeratiin 19:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CAFrench (Canada)Cytokératine 19:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FRFrench (France)Cyfra 21:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BEFrench (Belgium)Cytokératine 19:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-ITItalian (Italy)Citocheratina 19:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KRKorean (Korea, Republic Of)사이토케라틴 19:질량농도:검사시점:혈청/혈장:정량:
nl-NLDutch (Netherlands)cytokeratine 19:massa/volume:moment:serum of plasma:kwantitatief:
pl-PLPolish (Poland)Cytokeratyna 19:stężenie masowe:punkt w czasie:surowica lub osocze:ilościowy:
pt-BRPortuguese (Brazil)Citoqueratina 19:MCnc:Pt:Sor/Plas:Qn:
Synonyms: ; CK 19; Cyfra 21-1; Autoimmune hepatitis; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Chemistry
ru-RURussian (Russian Federation)Цитокератин 19:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TRTurkish (Turkey)Sitokeratin 19:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CNChinese (China)细胞角蛋白 19:质量浓度:时间点:血清/血浆:定量型:
Synonyms: CK 19;Cyfra 21-1;细胞角蛋白-19 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 水平;浓度;质量浓度(单位体积) 自身免疫型肝炎;自身免疫性肝炎 血清或血浆

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=25390-6