266-7
Gentamicin [Susceptibility] by Minimum lethal concentration (MLC)
Active
Part Description
LP15747-6 Gentamicin
Gentamicin is an aminoglycoside antibiotic, which has a bactericidal mode of action binding to the ribosome and various ribozymes to inhibit protein synthesis. Gentamicin is a hydrophilic molecule and is considered to have limited capacity to penetrate eukaryotic cells. Administered intravenously or intramuscularly, gentamicin is used to treat many bacterial infections, particularly gram-negative organisms such as meningitis, and infections of the blood, abdomen, lungs, skin, bones, joints and urinary tract, and is often used to treat severe cases of tularemia and the plague. The effect of gentamicin is mediated through the production of reactive oxygen species (ROS), which causes destablization of iron-sulfur (Fe-S) clusters and generates toxic, bactericidal compounds through the Fenton reaction. Gentamicin may cause kidney, nerve and severe hearing problems. More common side effects include nausea, headache, fever, rash and hoarseness. PMID: 26503658 [MedlinePlus Drug:a682275]
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Gentamicin
- Property
- Susc
- Time
- Pt
- System
- Isolate
- Scale
- Qn
- Method
- MLC
Additional Names
- Short Name
- Gentamicin Islt MLC
- Display Name
- Gentamicin MLC [Susc]
- Consumer Name Alpha Get Info
- Susceptibility to Gentamicin
Basic Attributes
- Class
- ABXBACT
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 14261
Member of these Panels
LOINC | Long Common Name |
---|---|
87927-0 | Bacterial susceptibility panel - Isolate by Minimum lethal concentration (MLC) |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG41057-7 | GentamicinSusc| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-DE | German (Germany) | Gentamicin: |
es-AR | Spanish (Argentina) | gentamicina: |
es-ES | Spanish (Spain) | Gentamicina: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Gentamicina: |
et-EE | Estonian (Estonia) | Gentamütsiin: Synonyms: Isolaat Juhuslik Kvantitatiivne Minimaalne letaalne kontsentratsioon Tundlikkus |
fr-CA | French (Canada) | Gentamicine: |
fr-FR | French (France) | Gentamicine: |
fr-BE | French (Belgium) | Gentamicine: |
it-IT | Italian (Italy) | Gentamicina: Synonyms: Concentrazione minima letale (MLC) Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici |
ko-KR | Korean (Korea, Republic Of) | 겐타마이신: |
nl-NL | Dutch (Netherlands) | gentamicine: Synonyms: MLC |
pt-BR | Portuguese (Brazil) | Gentamicina: Synonyms: c213; |
tr-TR | Turkish (Turkey) | Gentamisin: |
zh-CN | Chinese (China) | 庆大霉素: Synonyms: 分离物; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=266-7
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright