266-7

Gentamicin [Susceptibility] by Minimum lethal concentration (MLC)

Active

Part Description

LP15747-6 Gentamicin
Gentamicin is an aminoglycoside antibiotic, which has a bactericidal mode of action binding to the ribosome and various ribozymes to inhibit protein synthesis. Gentamicin is a hydrophilic molecule and is considered to have limited capacity to penetrate eukaryotic cells. Administered intravenously or intramuscularly, gentamicin is used to treat many bacterial infections, particularly gram-negative organisms such as meningitis, and infections of the blood, abdomen, lungs, skin, bones, joints and urinary tract, and is often used to treat severe cases of tularemia and the plague. The effect of gentamicin is mediated through the production of reactive oxygen species (ROS), which causes destablization of iron-sulfur (Fe-S) clusters and generates toxic, bactericidal compounds through the Fenton reaction. Gentamicin may cause kidney, nerve and severe hearing problems. More common side effects include nausea, headache, fever, rash and hoarseness. PMID: 26503658 [MedlinePlus Drug:a682275] Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Gentamicin:Susc:Pt:Isolate:Qn:MLC
Long Common Name: Gentamicin [Susceptibility] by Minimum lethal concentration (MLC)
Short Name: Gentamicin Islt MLC
Display Name: Gentamicin MLC [Susc]
Consumer Name Alpha Get Info: Susceptibility to Gentamicin

Part Model Get Info

Component
Gentamicin
LP15747-6
- Analyte
  Gentamicin
  LP15747-6
  - Component Numerator
    Gentamicin
    LP15747-6
    - Component Numerator Core
      Gentamicin
      LP15747-6
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Susc
LP6870-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Isolate
LP7370-2
- System Core
  Isolate
  LP7370-2
- Super System
  NULL
Scale
Qn
LP7753-9
Method
MLC
LP6402-4

Basic Attributes

Class: ABXBACT
Type: Laboratory
First Released: Version 1.0
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Observation
Common Test Rank Get Info: 14261

Member of these Panels

LOINC	Long Common Name
87927-0	Bacterial susceptibility panel - Isolate by Minimum lethal concentration (MLC)

Member of these Groups Get Info

LOINC Group	Group Name
LG41057-7	GentamicinSusc\|Isolate

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Gentamicin:Citlivost (mikroorganismy):Časový bod:Izolát:Kvantitativní:Minimální letální koncentrace (MLC)
de-DE	German (Germany)	Gentamicin:Empfindlichkeit (Mikroorganismen):Zeitpunkt:Isolat:Quantitativ:Minimale letale Konzentration (MLK)
el-GR	Greek (Greece)	Γενταμυκίνη:Susc:Pt:Απομονωμένο στέλεχος:Qn:MLC Synonyms: ABXBACT MLC Pt Qn Susc Απομονωμένο στέλεχος Γενταμυκίνη
es-AR	Spanish (Argentina)	gentamicina:susceptibilidad:punto en el tiempo:cepa clínica:cuantitativo:concentración letal mínima
es-ES	Spanish (Spain)	Gentamicina:Susceptibilidad:Punto temporal:Aislado:Qn:Concentración mínima bactericida (CMB) Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Gentamicina:Susceptibilidad (microorganismos):Punto temporal:Aislado:Cuantitativo:Concentración mínima letal (MLC)
et-EE	Estonian (Estonia)	Gentamütsiin:Susc:Pt:Is:Qn:MLK Synonyms: Isolaat Juhuslik Kvantitatiivne Minimaalne letaalne kontsentratsioon Tundlikkus
fr-CA	French (Canada)	Gentamicine:Susceptibilité:Temps ponctuel:Isolat:Quantitatif:CLM
fr-FR	French (France)	Gentamicine:Sensibilité:Ponctuel:Isolat:Numérique:Concentration minimale létale
fr-BE	French (Belgium)	Gentamicine:Susceptibilité:Temps ponctuel:Isolat:Quantitatif:CLM
it-IT	Italian (Italy)	Gentamicina:Susc:Pt:Isolato:Qn:MLC Synonyms: Concentrazione minima letale (MLC) Punto nel tempo (episodio) Sensibilità (microrganismi) Suscettibilità agli antibiotici
ko-KR	Korean (Korea, Republic Of)	겐타마이신:감수성:검사시점:분리주:정량:억제치사농도
nl-NL	Dutch (Netherlands)	gentamicine:gevoeligheid:moment:isolaat:kwantitatief:minimaal dodelijke concentratie Synonyms: MLC
pl-PL	Polish (Poland)	Gentamycyna:wrażliwość:punkt w czasie:izolat:ilościowy:minimalne stężenie śmiertelne, MLC Synonyms: wrażliwość (mikroorganizmów)
pt-BR	Portuguese (Brazil)	Gentamicina:Susc:Pt:Isolado:Qn:Concentração letal mínima Synonyms: c213; Gent; Garamycin; Genj; Genirr; Susceptibility; Susceptibilty; Sus; Suscept; Susceptibilities; Point in time; Random; Islt; Isol; Quantitative; QNT; Quant; Quan; MBC; Minimum bactericidal concentration; Minimum lethal concentration; ANTIBIOTIC SUSCEPTIBILITIES
tr-TR	Turkish (Turkey)	Gentamisin:Duyr:Zmlı:İzolat:Kant:MLC
zh-CN	Chinese (China)	庆大霉素:抗生素敏感性:时间点:分离株:定量型:最小致死浓度法 Synonyms: 分离物;分离菌;分离菌株;隔离种群可用数量表示的;定量性;数值型;数量型;连续数值型标尺抗生素敏感性(微生物);敏感性;某种抗微生物制剂对于某个分离株的影响;药物敏感性;药物敏感性(微生物) 抗生素敏感性试验;药敏;药敏类;药敏试验;药敏试验类时刻;随机;随意;瞬间最低杀菌浓度;最低杀菌浓度（Minimum bactericidal concentration，MBC）;最低杀菌浓度法;最低致死浓度;最低致死浓度（Minimum Lethal Concentration，MLC）;最低致死浓度法;最小杀菌浓度;最小杀菌浓度（Minimum bactericidal concentration，MBC）;最小杀菌浓度法;最小致死浓度;最小致死浓度（Minimum Lethal Concentration，MLC）正泰霉素;艮他霉素

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.