26685-8

3-Hydroxyisovalerate [Presence] in Urine

Active

Part Description

LP15301-2 3-Hydroxyisovalerate
3-Hydroxyisovaleric acid is a normal human metabolite excreted in the urine. Elevated levels of this compound are found in several inherited disorders such as Dihydrolipoamide dehydrogenase Deficiency, 3-Methylcrotonyl-CoA carboxylase 1 deficiency, 3-Hydroxy-3-methylglutaryl-CoA lyase deficiency (3-hydroxy-3-methylglutaryl -CoA lyase Deficiency, Biotinidase deficiency multiple carboxylase deficiency late-onset , Late onset multiple carboxylase deficiency, HolMcarboxylase synthetase deficiency, 3-Methylcrotonyl-CoA carboxylase 2 deficiency. 3-Hydroxyisovaleric acid is also elevated in smokers, in subjects undergoing long-term anticonvulsant therapy with carbamazepine and/or phenytoin. These levels are elevated due to impairment of renal reclamation of biotin. Levels may also be increased from prolonged consumption of raw egg-whites PMID: 16895887, PMID: 9523856, PMID: 15447901, PMID: 9176832, [OMIM: 210210], [OMIM: 253270], [OMIM: 600529], [OMIM: 253260], [OMIM: 246450], [OMIM: 210200], [OMIM: 238331] Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Human Metabolome Database

LOINC Names Get Info

Fully-Specified Name: 3-Hydroxyisovalerate:PrThr:Pt:Urine:Ord:
Long Common Name: 3-Hydroxyisovalerate [Presence] in Urine
Short Name: 3OH-Isovalerate Ur Ql
Display Name: 3-Hydroxyisovalerate Ql (U)
Consumer Name Alpha Get Info: 3-Hydroxyisovalerate, Urine

Part Model Get Info

Component
3-Hydroxyisovalerate
LP15301-2
- Analyte
  3-Hydroxyisovalerate
  LP15301-2
  - Component Numerator
    3-Hydroxyisovalerate
    LP15301-2
    - Component Numerator Core
      3-Hydroxyisovalerate
      LP15301-2
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Urine
LP7681-2
- System Core
  Urine
  LP7681-2
- Super System
  NULL
Scale
Ord
LP7751-3
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.00
Last Updated: Version 2.73 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Observation
Common Test Rank Get Info: 12735

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	3-hydroxyizovalerát:Přítomnost nebo práh:Časový bod:Moč:Ordinální:
de-AT	German (Austria)	Synonyms: 3-Hydroxyisovalerate /U
el-GR	Greek (Greece)	3-υδροξυϊσοβαλεριανικό:PrThr:Pt:Ούρα:Ord: Synonyms: 3-υδροξυϊσοβαλεριανικό CHEM Ord PrThr Pt Ούρα
es-AR	Spanish (Argentina)	3-hidroxiisovalerato:concentración arbitraria:punto en el tiempo:orina:ordinal:
es-ES	Spanish (Spain)	3-Hidroxiisovalerato:PrThr:Punto temporal:Orina:Ord:
es-MX	Spanish (Mexico)	3-hidroxiisovalerato:Presencia o umbral:Punto temporal:Orina:Ordinal:
et-EE	Estonian (Estonia)	3-hüdroksüisovaleraat:PrThr:Pt:U:Ord: Synonyms: Järgarvuline Juhuslik Uriin
fr-CA	French (Canada)	3-hydroxyisovalérate:Présence-Seuil:Temps ponctuel:Urine:Ordinal:
fr-FR	French (France)	3-hydroxyisovalérate:Présence/Seuil:Ponctuel:Urine:Qualitatif:
fr-BE	French (Belgium)	3-hydroxyisovalérate:PrThr:Temps ponctuel:Urine:Ordinal:
it-IT	Italian (Italy)	3-Idrossiisovalerato:PrThr:Pt:Urine:Ord: Synonyms: Chimica Presenza o Soglia Punto nel tempo (episodio)
ko-KR	Korean (Korea, Republic Of)	3-하이드록시이소발레레이트:임의농도:검사시점:뇨:순위척도:
nl-NL	Dutch (Netherlands)	3-hydroxyisovaleraat:aanwezigheid:moment:urine:ordinaal:
pl-PL	Polish (Poland)	3-Hydroksyizowalerian:granica wykrywalności:punkt w czasie:mocz:uporządkowany:
pt-BR	Portuguese (Brazil)	3-Hidroxisovalerato:ACnc:Pt:Urina:Ord: Synonyms: ; 3OH-Isovalerate; 3-hydroxy-isovalerate; 3-HIA; 3-hydroxyisovaleric acid; Arbitrary concentration; Point in time; Random; Ur; UR; Urn; UA; Ql; Ordinal; QL; Qualitative; Qual; Screen; III; Chemistry
ru-RU	Russian (Russian Federation)	3-Гидроксиизовалерат:PrThr:ТчкВрм:Моча:Пор: Synonyms: Порядковый Точка во времени;Момент
tr-TR	Turkish (Turkey)	3-Hidroksiizovalerat:MevcEşik:Zmlı:İdrar:Srl: Synonyms: Mevcut
zh-CN	Chinese (China)	3-羟基异戊酸:存在情况或阈值:时间点:尿液:序数型: Synonyms: 3-HIA;3OH-异戊酸;3-羟基-异戊酸 Ⅲ III 三依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类叁存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）尿;小便;下泉时刻;随机;随意;瞬间

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.