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Part Description

LP16650-1   Histoplasma capsulatum
Histoplasmosis capsulatum is a dimorphic fungal pathogen with filamentous or yeast forms,depending on nutritional factors and temperature.The M antigen is a well-known glycoprotein used as a diagnostic antigen for acute histoplasmosis as it induces the first precipitins during disease. Monoclonal antibodies (mAbs) to the M antigen have been found to modify the pathogenesis of histoplasmosis.Given the shortcomings of current therapies, the administration of mAbs is being investigated. PMID: 22347215 The H band is less commonly seen than the M band and is indicative of chronic or severe acute infections with H capsulatum.

H. capsulatum is found in nature primarily as a saprophytic mold. The mold form is comprised of hyaline septate hyphae, which produce two different asexual reproduction structures, macroconidia and microconidia. The micronidia are believed to be responsible for disease propagation since their 2-6 µm size is well suited for disposition into the distal alveoli. Infection is typically acquired through inhalation of fungal propagules upon disturbances of contaminated soil or excreta. Environmental and genetic factors influence disease manifestations which can range from asymptomatic or mild influenza-like disease to a disseminated sepsis form. Manifestations depend on the magnitude of exposure, the host's immunological status and the virulence of the infective strain. Reactivation of latent infection can result in significant disease, particularly for immunosuppressed individuals. Despite the availability of potent antifungal drugs, nearly one in ten patients hospitalized with histoplasmosis dies. PMID: 17223625 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Histoplasma capsulatum Ab:Titr:Pt:Ser:SemiQn:Immune diffusion
Long Common Name
Histoplasma capsulatum Ab [Titer] in Serum by Immune diffusion (ID)
Short Name
H capsul Ab Titr Ser ID
Display Name
H. capsulatum Ab Immune diff (S) [Titer]
Consumer Name Alpha Get Info
Histoplasma capsulatum antibody, Blood

Part Model Get Info

  • Component
    Histoplasma capsulatum Ab
    LP38405-4
    • Analyte
      Histoplasma capsulatum Ab
      LP38405-4
      • Component Numerator
        Histoplasma capsulatum Ab
        LP38405-4
        • Component Numerator Core
          Histoplasma capsulatum
          LP16650-1
        • Component Numerator Core Suffix
          Ab
          LP20667-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Titr
    LP6881-9
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    SemiQn
    LP436123-6
  • Method
    Immune diffusion
    LP6322-4

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.00
Last Updated
Version 2.75 (MAJ)
Order vs. Observation
Both
Common Test Rank Get Info
4615

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Histoplasma capsulatum Ab:Arbitrární koncentrace (titr):Časový bod:Sérum:Semikvantitativní:Imunodifuze (ID)
el-GRGreek (Greece)Histoplasma capsulatum (Ιστόπλασμα) Αντίσωμα:Titr:Pt:Ορός:Ημιποσοτική:Ανοσοδιάχυση
Synonyms: Histoplasma capsulatum (Ιστόπλασμα) MICRO Pt Titr Ανοσοδιάχυση Αντίσωμα Ημιποσοτική Ορός
es-ARSpanish (Argentina)[anticuerpo anti - ] especie de Histoplasma [Ac]:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:difusión inmunitaria
es-ESSpanish (Spain)Histoplasma capsulatum Anticuerpos:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:Inmunodifusión
Synonyms: Semicuantitativo
es-MXSpanish (Mexico)Histoplasma capsulatum Ab:Título:Punto temporal:Suero:Cuantitativo:Difusión inmunitaria (ID)
fr-CAFrench (Canada)Histoplasma capsulatum, Ac:Titre:Temps ponctuel:Sérum:SemiQn:Immunodiffusion
fr-FRFrench (France)Histoplasma capsulatum Ac:Titre:Ponctuel:Sérum:Semi-Quantitatif:Immunodiffusion
it-ITItalian (Italy)Histoplasma capsulatum Ab:Titr:Pt:Siero:SemiQn:Immuno diffusione
Synonyms: anticorpo Immuno diffusione (ID) Microbiologia Punto nel tempo (episodio) Siero Titolo
ko-KRKorean (Korea, Republic Of)히스토플라스마 캡슐라툼 항체:역가:검사시점:혈청:정량:면역 확산
nl-NLDutch (Netherlands)Histoplasma capsulatum As:titer:moment:serum:semikwantitatief:immunodiffusie
Synonyms: antistof; antilichaam
pt-BRPortuguese (Brazil)Histoplasma capsulatum Ac:Título:Pt:Soro:Qn:Imunodifusão
Synonyms: ; H capsul; H capsulatum; H farciminosum; Histoplasma farciminosum; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; ID; Immunodiff; Immunodiffusion; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Imun; Imune; Imm; Histo; Histopl; Histoplasmos; Histoplasmosis; Microbiology
zh-CNChinese (China)荚膜组织胞浆菌 抗体:滴定度:时间点:血清:半定量型:免疫扩散法
Synonyms: Ab;自身抗体 免疫扩散 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 皮疽组织胞浆菌 Ab 皮疽组织胞浆菌;美洲型组织胞浆菌;鼻疽性组织浆菌 皮疽组织胞浆菌抗体 组织胞浆菌属 组织胞浆菌病 美洲型组织胞浆菌 Ab 美洲型组织胞浆菌抗体 荚膜组织胞浆菌 Ab 鼻疽性组织浆菌 Ab 鼻疽性组织浆菌抗体

Example Units

UnitSource
titerREGENSTRIEF
{titer}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=27266-6