28061-0
Naloxone [Mass/volume] in Serum or Plasma
Active
Part Description
LP28525-1 Naloxone
Naloxone is a pure opioid antagonist and, when taken at recommended doses, has no physiological effects in the absence of an opioid agonist. Intravenous naloxone becomes effective within two minutes of injection, but oral or sublingual naloxone has little effect due to its poor absorption. Therefore, intravenous naloxone is used to treat opioid overdose, and it is used as a sublingual combination with buprenorphine, an opioid agonist-antagonist used to treat chronic opioid-dependence, to lower buprenorphine's abuse potential as follows: when the combination is taken sublingually as prescribed, naloxone exerts little effect and buprenorphine's effects predominate; however, if crushed and injected intravenously, naloxone's antagonist properties reverse the agonist effects of buprenorphine and can precipitate withdrawal. PMID: 19368419 Nalaxone levels along with its inactive metabolite, naloxone-3-glucuronide (N3G), may be measured to monitor compliance or identify illicit opioid drug use.
Source: Regenstrief LOINC, PMID: 19368419
Fully-Specified Name
- Component
- Naloxone
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Naloxone SerPl-mCnc
- Display Name
- Naloxone [Mass/Vol]
- Consumer Name Alpha Get Info
- Naloxone, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.00
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 19483
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG37627-3 | Naloxone| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-MX | Spanish (Mexico) | Naloxona: |
es-AR | Spanish (Argentina) | naloxona: |
es-ES | Spanish (Spain) | Naloxona: Synonyms: Cuantitativo |
et-EE | Estonian (Estonia) | Naloksoon: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
fr-CA | French (Canada) | Naloxone: |
fr-FR | French (France) | Naloxone: |
fr-BE | French (Belgium) | Naloxone: |
it-IT | Italian (Italy) | Naloxone: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
ko-KR | Korean (Korea, Republic Of) | 날록손: |
nl-NL | Dutch (Netherlands) | naloxon: |
pt-BR | Portuguese (Brazil) | Naloxone: Synonyms: Narcan; |
ru-RU | Russian (Russian Federation) | Налоксон: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
tr-TR | Turkish (Turkey) | Nalokzon: |
zh-CN | Chinese (China) | 钠洛酮: Synonyms: C19H21NO4; |
Example Units
Unit | Source |
---|---|
mg/mL | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=28061-0
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright