28061-0

Naloxone [Mass/volume] in Serum or Plasma

Active

Part Description

LP28525-1 Naloxone
Naloxone is a pure opioid antagonist and, when taken at recommended doses, has no physiological effects in the absence of an opioid agonist. Intravenous naloxone becomes effective within two minutes of injection, but oral or sublingual naloxone has little effect due to its poor absorption. Therefore, intravenous naloxone is used to treat opioid overdose, and it is used as a sublingual combination with buprenorphine, an opioid agonist-antagonist used to treat chronic opioid-dependence, to lower buprenorphine's abuse potential as follows: when the combination is taken sublingually as prescribed, naloxone exerts little effect and buprenorphine's effects predominate; however, if crushed and injected intravenously, naloxone's antagonist properties reverse the agonist effects of buprenorphine and can precipitate withdrawal. PMID: 19368419 Nalaxone levels along with its inactive metabolite, naloxone-3-glucuronide (N3G), may be measured to monitor compliance or identify illicit opioid drug use. Source: Regenstrief LOINC, PMID: 19368419

LOINC Names Get Info

Fully-Specified Name: Naloxone:MCnc:Pt:Ser/Plas:Qn:
Long Common Name: Naloxone [Mass/volume] in Serum or Plasma
Short Name: Naloxone SerPl-mCnc
Display Name: Naloxone [Mass/Vol]
Consumer Name Alpha Get Info: Naloxone, Blood

Part Model Get Info

Component
Naloxone
LP28525-1
- Analyte
  Naloxone
  LP28525-1
  - Component Numerator
    Naloxone
    LP28525-1
    - Component Numerator Core
      Naloxone
      LP28525-1
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 2.00
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Both
Common Test Rank Get Info: 19483

Member of these Groups Get Info

LOINC Group	Group Name
LG37627-3	Naloxone\|ANYProp\|ANYTm\|ANYSys\|ANYMeth

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Naloxon:Hmotnostní koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
el-GR	Greek (Greece)	Ναλοξόνη:MCnc:Pt:Ορός/Πλάσμα:Qn: Synonyms: DRUG/TOX MCnc Pt Qn Ναλοξόνη Ορός Ορός/Πλάσμα Πλάσμα
es-MX	Spanish (Mexico)	Naloxona:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
es-AR	Spanish (Argentina)	naloxona:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-ES	Spanish (Spain)	Naloxona:Concentración de masa:Punto temporal:Suero o Plasma:Qn: Synonyms: Cuantitativo
et-EE	Estonian (Estonia)	Naloksoon:MCnc:Pt:S/P:Qn: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA	French (Canada)	Naloxone:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR	French (France)	Naloxone:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE	French (Belgium)	Naloxone:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT	Italian (Italy)	Naloxone:MCnc:Pt:Siero/Plasma:Qn: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR	Korean (Korea, Republic Of)	날록손:질량농도:검사시점:혈청/혈장:정량:
nl-NL	Dutch (Netherlands)	naloxon:massa/volume:moment:serum of plasma:kwantitatief:
pt-BR	Portuguese (Brazil)	Naloxone:MCnc:Pt:Sor/Plas:Qn: Synonyms: Narcan; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU	Russian (Russian Federation)	Налоксон:МассКонц:ТчкВрм:Сыв/Плаз:Колич: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	Nalokzon:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CN	Chinese (China)	钠洛酮:质量浓度:时间点:血清/血浆:定量型: Synonyms: C19H21NO4;纳洛酮;那诺松可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间毒品毒品类水平;浓度;质量浓度(单位体积) 药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类血清或血浆

Example Units

Unit	Source
mg/mL	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=28061-0

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.