28610-4

Sarcosine/Creatinine [Ratio] in Urine

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Part Descriptions

LP15859-9   Sarcosine
Sarcosine is the N-methyl derivative of glycine. It is a natural amino acid found in muscles and other body tissues. In the laboratory, it may be synthesized from chloroacetic acid and methylamine. Sarcosine is found naturally as an intermediate in the metabolism of choline to glycine. Sarcosine is sweet to the taste and dissolves in water. It is used in manufacturing biodegradable surfactants and toothpastes as well as in other applications. Sarcosine is ubiquitous in biological materials and is present in such foods as egg yolks, turkey, ham, vegetables, legumes, etc. Sarcosine is reported to be formed from dietary intake of choline and from the metabolism of methionine and is rapidly degraded to glycine, which, in addition to its importance as a constituent of protein, plays a significant role in various physiological processes as a prime metabolic source of components of living cells such as glutathione, creatine, purines and serine.

Sarcosinemia can result from severe folate deficiency because of the folate requirement for the conversion of sarcosine to glycine. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Sarcosine (Wikipedia)

LP15859-9   Sarcosine
An amino acid intermediate in the metabolism of choline. Source: National Library of Medicine, MeSH 2006

LP15859-9   Sarcosine
High levels of sarcosine may occur as a result of vitamin B2 insufficiency as vitamin B2 is required to metabolize sarcosine. Information from Metamatrix Clinical Laboratory 2006 12 01. Source: Regenstrief Institute

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Fully-Specified Name

Component

Sarcosine/Creatinine

Property

Ratio

Time

Pt

System

Urine

Scale

Qn

Method

Additional Names

Short Name

Sarcosine/Creat Ur-Rto

Display Name

Sarcosine/Creatinine (U) [Ratio]

Consumer Name Alpha Get Info

Sarcosine/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.00

Last Updated

Version 2.73

Order vs. Observation

Observation

Common Test Rank Get Info

6372

Member of these Panels

Language Variants Get Info

Related Names

• Chemistry
• CR
• Crea
• Creat
• Point in time
• QNT
• Quan
• Quant
• Quantitative
• Random
• Ratios
• Rto
• Sar
• Sarc
• UA
• UCr
• UR
• Urn

Example Units

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CodeSystem lookup

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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.