Version 2.80

Part Description

LP21368-3   Sirolimus
Sirolimus, also known as rapamycin, is a macrolide compound that inhibits lymphocyte proliferation and is used as an immunosuppressant to prevent rejection in organ transplantation. It inhibits T-cell activation and proliferation by inhibiting the response to interleukin 2 (IL-2). Its mode of action differs from that of other immunosuppressants (SN Sehga, Clin Biochem, 31:335, 1998) most notably by not being a calcineurin inhibitor. Its inhibitory action is mediated via a cytosolic protein, FK-binding protein 12. Sirolimus is variably absorbed; levels need to monitored to achieve the therapeutic target while avoiding toxic levels. Sirolimus is marketed under the trade name Rapamune. Source: Regenstrief LOINC

Reference Information

Type Source Reference
Mapping Guidance Regenstrief Help Bld is the preferred specimen Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations

Fully-Specified Name

Component
Sirolimus
Property
MCnc
Time
Pt
System
Bld
Scale
Qn
Method

Additional Names

Long Common Name
Sirolimus [Mass/volume] in Blood
Short Name
Sirolimus Bld-mCnc
Display Name
Sirolimus (Bld) [Mass/Vol]
Consumer Name Alpha Get Info
Sirolimus, Blood

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.03
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Both
Common Test Rank Get Info
828

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Sirolimus:Massenkonzentration:Zeitpunkt:Blut:Quantitativ:
de-AT German (Austria) Synonyms: Sirolimus
el-GR Greek (Greece) Σιρόλιμους:MCnc:Pt:Αίμα:Qn:
Synonyms: MCnc
es-ES Spanish (Spain) Sirolimus:Concentración de masa:Punto temporal:Sangre:Qn:
Synonyms: Cuantitativo
es-AR Spanish (Argentina) sirolimus:concentración de masa:punto en el tiempo:sangre:cuantitativo:
es-MX Spanish (Mexico) Sirolimus:Concentración de masa:Punto temporal:Sangre:Cuantitativo:
et-EE Estonian (Estonia) Siroliimus:MCnc:Pt:B:Qn:
Synonyms: Juhuslik Kvantitatiivne Veri
fr-CA French (Canada) Sirolimus:Concentration de masse:Temps ponctuel:Sang:Quantitatif:
fr-FR French (France) Sirolimus:Masse/Volume:Ponctuel:Sang:Numérique:
fr-BE French (Belgium) Sirolimus:Concentration de masse:Temps ponctuel:Sang:Quantitatif:
it-IT Italian (Italy) Sirolimus:MCnc:Pt:Sangue:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio) Sangue
ko-KR Korean (Korea, Republic Of) 시롤리무스:질량농도:검사시점:전혈:정량:
nl-NL Dutch (Netherlands) sirolimus:massa/volume:moment:bloed:kwantitatief:
pt-BR Portuguese (Brazil) Sirolimus:MCnc:Pt:SgTotal:Qn:
Synonyms: SRL; Rapamycin; Rapamune; Mass concentration; Level; Point in time; Random; Blood; WB; Whole blood; Quantitative; QNT; Quant; Quan; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU Russian (Russian Federation) Сиролимус:МассКонц:ТчкВрм:Кр:Колич:
Synonyms: Количественный Кровь Массовая концентрация Рапамицин Точка во времени;Момент
tr-TR Turkish (Turkey) Sirolimus:KütlKons:Zmlı:Kan:Kant:
zh-CN Chinese (China) 西罗莫司:质量浓度:时间点:全血:定量型:
Synonyms: 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 瑞帕霉素;雷帕霉素 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血;血液

Example Units

Unit Source
ng/mL Example UCUM Units
ng/mL REGENSTRIEF
ug/L eCHN

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=29247-4