29247-4

Sirolimus [Mass/volume] in Blood

Active

Part Description

LP21368-3 Sirolimus
Sirolimus, also known as rapamycin, is a macrolide compound that inhibits lymphocyte proliferation and is used as an immunosuppressant to prevent rejection in organ transplantation. It inhibits T-cell activation and proliferation by inhibiting the response to interleukin 2 (IL-2). Its mode of action differs from that of other immunosuppressants (SN Sehga, Clin Biochem, 31:335, 1998) most notably by not being a calcineurin inhibitor. Its inhibitory action is mediated via a cytosolic protein, FK-binding protein 12. Sirolimus is variably absorbed; levels need to monitored to achieve the therapeutic target while avoiding toxic levels. Sirolimus is marketed under the trade name Rapamune. Source: Regenstrief LOINC

Reference Information

Type	Source	Reference
Mapping Guidance	Regenstrief Help	Bld is the preferred specimen Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations

LOINC Names Get Info

Fully-Specified Name: Sirolimus:MCnc:Pt:Bld:Qn:
Long Common Name: Sirolimus [Mass/volume] in Blood
Short Name: Sirolimus Bld-mCnc
Display Name: Sirolimus (Bld) [Mass/Vol]
Consumer Name Alpha Get Info: Sirolimus, Blood

Part Model Get Info

Component
Sirolimus
LP21368-3
- Analyte
  Sirolimus
  LP21368-3
  - Component Numerator
    Sirolimus
    LP21368-3
    - Component Numerator Core
      Sirolimus
      LP21368-3
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Bld
LP7057-5
- System Core
  Bld
  LP7057-5
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 2.03
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Both
Common Test Rank Get Info: 828

Language Variants Get Info

Tag	Language	Translation
ar-JO	Arabic (Jordan)	السيروليماس في الدم ( بتقنية الكتلة / الحجم )
cs-CZ	Czech (Czechia)	Sirolimus:Hmotnostní koncentrace:Časový bod:Krev:Kvantitativní:
de-AT	German (Austria)	Synonyms: Sirolimus
de-DE	German (Germany)	Sirolimus:Massenkonzentration:Zeitpunkt:Blut:Quantitativ:
el-GR	Greek (Greece)	Σιρόλιμους:MCnc:Pt:Αίμα:Qn: Synonyms: DRUG/TOX MCnc Pt Qn Αίμα Σιρόλιμους
es-AR	Spanish (Argentina)	sirolimus:concentración de masa:punto en el tiempo:sangre:cuantitativo:
es-ES	Spanish (Spain)	Sirolimus:Concentración de masa:Punto temporal:Sangre:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Sirolimus:Concentración de masa:Punto temporal:Sangre:Cuantitativo:
et-EE	Estonian (Estonia)	Siroliimus:MCnc:Pt:B:Qn: Synonyms: Juhuslik Kvantitatiivne Veri
fr-CA	French (Canada)	Sirolimus:Concentration de masse:Temps ponctuel:Sang:Quantitatif:
fr-FR	French (France)	Sirolimus:Masse/Volume:Ponctuel:Sang:Numérique:
fr-BE	French (Belgium)	Sirolimus:Concentration de masse:Temps ponctuel:Sang:Quantitatif:
it-IT	Italian (Italy)	Sirolimus:MCnc:Pt:Sangue:Qn: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio) Sangue
ko-KR	Korean (Korea, Republic Of)	시롤리무스:질량농도:검사시점:전혈:정량:
nl-NL	Dutch (Netherlands)	sirolimus:massa/volume:moment:bloed:kwantitatief:
pt-BR	Portuguese (Brazil)	Sirolimus:MCnc:Pt:SgTotal:Qn: Synonyms: SRL; Rapamycin; Rapamune; Mass concentration; Level; Point in time; Random; Blood; WB; Whole blood; Quantitative; QNT; Quant; Quan; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU	Russian (Russian Federation)	Сиролимус:МассКонц:ТчкВрм:Кр:Колич: Synonyms: Количественный Кровь Массовая концентрация Рапамицин Точка во времени;Момент
tr-TR	Turkish (Turkey)	Sirolimus:KütlKons:Zmlı:Kan:Kant:
zh-CN	Chinese (China)	西罗莫司:质量浓度:时间点:全血:定量型: Synonyms: 可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间毒品毒品类水平;浓度;质量浓度(单位体积) 瑞帕霉素;雷帕霉素药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类血;血液

Example Units

Unit	Source
ng/mL	Example UCUM Units
ng/mL	REGENSTRIEF
ug/L	eCHN

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=29247-4

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.