29886-9

Encephalomyocarditis virus neutralizing antibody [Titer] in Serum by Neutralization test

Active

Part Descriptions

LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP28501-2 Encephalomyocarditis virus
Encephalomyocarditis virus (EMCV) is a small non-enveloped, positive single-strand RNA virus that belongs to the Picornaviridae family. EMCV is known to have infected voles, squirrels, elephants, swine, wild boar, racoons, antelope, lions, birds, several species of non-human primates and humans. EMCV is found all around the world. Mice or rats are believed to be its natural reservoir. EMCV is transmitted in contaminated food, water and diseased carcasses. EMCV elicits an extreme inflammatory response that may enhance other virulence factors. EMCV virulence is linked to sex, age and animal species of the infected host as well as the EMCV viral strain itself. Symptoms of EMCV infection include myocarditis, diabetes, reproductive and neurological disorders. Severe symptoms rarely occur in humans infected with EMCV. PMID: 2272247 Source: Regenstrief LOINC

LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Encephalomyocarditis virus Ab.Neut:Titr:Pt:Ser:SemiQn:Neut
Long Common Name: Encephalomyocarditis virus neutralizing antibody [Titer] in Serum by Neutralization test
Short Name: EMCV NAb Titr Ser Nt
Display Name: Encephalomyocarditis virus neut ab Neut test (S) [Titer]
Consumer Name Alpha Get Info: Encephalomyocarditis virus neutralizing antibody, Blood

Part Model Get Info

Component
Encephalomyocarditis virus Ab.Neut
LP430383-2
- Analyte
  Encephalomyocarditis virus Ab.Neut
  LP430383-2
  - Component Numerator
    Encephalomyocarditis virus Ab.Neut
    LP430383-2
    - Component Numerator Core
      Encephalomyocarditis virus
      LP28501-2
    - Component Numerator Core Suffix
      Ab.Neut
      LP207365-0
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Titr
LP6881-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
SemiQn
LP436123-6
Method
Neut
LP6416-4

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.04
Last Updated: Version 2.75 (MAJ)
Change Reason: Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.;
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Encephalomyocarditis virus Ab.neutralizační:Arbitrární koncentrace (titr):Časový bod:Sérum:Semikvantitativní:Neutralizační test
el-GR	Greek (Greece)	Ιός εγκεφαλομυοκαρδίτιδας Ab.Neut:Titr:Pt:Ορός:Ημιποσοτική:Ουδετερόφιλα Synonyms: Ab.Neut MICRO Pt Titr Αντίσωμα Ημιποσοτική Ιός Ιός εγκεφαλομυοκαρδίτιδας Ορός Ουδετερόφιλα
es-AR	Spanish (Argentina)	anticuerpo contra virus de la encefalomiocarditis:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:neutralización
es-ES	Spanish (Spain)	Virus de la encefalomiocarditis Anticuerpos antineutrófilos:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:Prueba de neutralización Synonyms: Semicuantitativo
es-MX	Spanish (Mexico)	Virus de la encefalomiocarditis Ab:Título:Punto temporal:Suero:Cuantitativo:Prueba de neutralización
fr-FR	French (France)	Encéphalomyocardite virus Ac neutralisant:Titre:Ponctuel:Sérum:Semi-Quantitatif:Neutralisation
fr-CA	French (Canada)	Virus encéphalomyélite Ac.neut:Titre:Temps ponctuel:Sérum:SemiQn:Test de neutralisation
it-IT	Italian (Italy)	Encephalomyocarditis virus Ab.Neut:Titr:Pt:Siero:SemiQn:Neut Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Siero Test di neutralizzazione Titolo
ko-KR	Korean (Korea, Republic Of)	뇌심장근육염 바이러스 항체:역가:검사시점:혈청:정량:중화
nl-NL	Dutch (Netherlands)	encephalomyocarditis-virus As.neutraliserend:titer:moment:serum:semikwantitatief:neutralisatietest Synonyms: antistof; antilichaam
pl-PL	Polish (Poland)	Wirus zapalenia mózgu i mięśnia sercowego Ab.Neutralizujące:miano:punkt w czasie:surowica:półilościowy:test neutralizacji Synonyms: Przeciwciała do wirusa zapalenia mózgu i mięśnia sercowego Przeciwciała neutralizujące do wirusa zapalenia mózgu i mięśnia sercowego Wirus zapalenia mózgu i mięśnia sercowego
pt-BR	Portuguese (Brazil)	Encefalomiocardite vírus Ac:Título:Pt:Soro:Qn:Teste de neutralização Synonyms: ; EMCV; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Nt; NT; Neutralization test; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
zh-CN	Chinese (China)	脑心肌炎病毒抗体.中和:滴定度:时间点:血清:半定量型:中和试验 Synonyms: Ab;自身抗体 EMCV EMCV Ab EMCV 抗体中和试验;中和抗体;中和传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数时刻;随机;随意;瞬间脑心肌炎病毒 Ab

Example Units

Unit	Source
{titer}	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=29886-9

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.