3027-0
Thyroxine (T4)/Thyroxine binding globulin [Mass Ratio] in Serum or Plasma
Active
Part Descriptions
LP15900-1 Thyroxine
The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosine (monoiodotyrosine) and the coupling of iodotyrosine (diiodotyrosine) in thyroglobulin. Thyroxine is separated from thyroglobulin by proteolysis and released in the blood. Thyroxine is peripherally deiodinated to form triiodothyronine which exerts broad stimulatory effects on cell metabolism.
Source: National Library of Medicine, MeSH 2006
LP32168-4 Thyroxine binding globulin
Thyroxine-binding globulin (TBG) is one of three proteins (along with transthyretin and albumin) responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3€™-triiodothyronine (T3) in the bloodstream. Of these three proteins, TBG has the highest affinity for T4 and T3, but is present in the lowest concentration. Despite its low concentration, TBG carries the majority of T4 in serum. Due to the very low serum concentration of T4 T3, TBG is rarely more than 25% saturated with its ligand. Unlike transthyretin and albumin, TBG has a single binding site for T4T3. Genomically, TBG is a serpin, although it has no inhibitory function like many other members of this class of proteins. TBG is synthesized primarily in the liver as a 54 kDa protein.
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Source: Wikipedia, Thyroxine binding globulin (Wikipedia)
Fully-Specified Name
- Component
- Thyroxine/Thyroxine binding globulin
- Property
- MRto
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- T4/T4BG SerPl
- Display Name
- T4/TBG [Mass ratio]
- Consumer Name Alpha Get Info
- T4/TBG, Blood
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73
- Order vs. Observation
- Observation
- Common Test Rank Get Info
- 10460
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-AR | Spanish (Argentina) | tiroxina/globulina fijadora de tiroxina: |
es-ES | Spanish (Spain) | Tiroxina/Tiroxina unida a la globulina: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Tiroxina / Globulina transportadora de tiroxina: |
et-EE | Estonian (Estonia) | Türoksiin/türoksiini siduv proteiin: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
fr-FR | French (France) | Thyroxine/thyroxine binding globulin: |
it-IT | Italian (Italy) | Tiroxina/Tiroxina, globulina legante: Synonyms: Chimica Globulina legante la tiroxina Plasma Punto nel tempo (episodio) Rapporto di Massa Siero Siero o Plasma |
ko-KR | Korean (Korea, Republic Of) | 티록신/티록신 결합 글로불린: |
nl-NL | Dutch (Netherlands) | thyroxine/thyroxinebindend globuline: |
pl-PL | Polish (Poland) | Tyroksyna/białko wiążące tyroksynę: |
pt-BR | Portuguese (Brazil) | Tiroxina/Globulina Transportadora da Tiroxina: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Тироксин/Тироксин связывающий глобулин: Synonyms: Количественный Масс отношение Плазма Сыворотка Сыворотка или Плазма Тироксинсвязывающий глобулин Тироксинсвязывающий глобулин; |
tr-TR | Turkish (Turkey) | Tiroksin/Tiroksin bağlayıcı globulin: |
zh-CN | Chinese (China) | 甲状腺素/甲状腺素结合球蛋白: Synonyms: T4; |
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