31021-9

Interferon.beta 1 neutralizing antibody [Titer] in Serum or Plasma by Neutralization test

Active

Part Descriptions

LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Interferon.beta 1 Ab.Neut:Titr:Pt:Ser/Plas:SemiQn:Neut
Long Common Name: Interferon.beta 1 neutralizing antibody [Titer] in Serum or Plasma by Neutralization test
Short Name: INF-B1 NAb Titr SerPl Nt
Display Name: Interferon.beta 1 neut ab Neut test [Titer]
Consumer Name Alpha Get Info: Interferon.beta 1 neutralizing antibody, Blood

Part Model Get Info

Component
Interferon.beta 1 Ab.Neut
LP430413-7
- Analyte
  Interferon.beta 1 Ab.Neut
  LP430413-7
  - Component Numerator
    Interferon.beta 1 Ab.Neut
    LP430413-7
    - Component Numerator Core
      Interferon.beta 1
      LP28891-7
    - Component Numerator Core Suffix
      Ab.Neut
      LP207365-0
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Titr
LP6881-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
SemiQn
LP436123-6
Method
Neut
LP6416-4

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.04
Last Updated: Version 2.75 (MAJ)
Change Reason: Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.;
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Interferon.beta 1 Ab.neutralizační:Arbitrární koncentrace (titr):Časový bod:Sérum/plazma:Semikvantitativní:Neutralizační test
el-GR	Greek (Greece)	Ιντερφερόνη.βήτα 1 Ab.Neut:Titr:Pt:Ορός/Πλάσμα:Ημιποσοτική:Ουδετερόφιλα Synonyms: Ab.Neut Pt SERO Titr Αντίσωμα Ημιποσοτική Ιντερφερόνη Ιντερφερόνη.β Ιντερφερόνη.βήτα 1 Ορός Ορός/Πλάσμα Ουδετερόφιλα Πλάσμα
es-AR	Spanish (Argentina)	anticuerpo contra interferón.beta 1:factor de dilución (titulación):punto en el tiempo:suero/plasma:cuantitativo:neutralización
es-ES	Spanish (Spain)	Interferonbeta 1 Anticuerpos antineutrófilos:Titulo / Factor de dilución:Punto temporal:Suero o Plasma:Semicuantitativo:Prueba de neutralización Synonyms: Semicuantitativo
es-MX	Spanish (Mexico)	Interferón beta 1 Ab:Título:Punto temporal:Suero o Plasma:Cuantitativo:Prueba de neutralización
fr-CA	French (Canada)	Interféron.bêta 1 Ac.neut:Titre:Temps ponctuel:Sérum/Plasma:SemiQn:Test de neutralisation
fr-FR	French (France)	Interféron bêta 1 Ac neutralisant:Titre:Ponctuel:Sérum/Plasma:Semi-Quantitatif:Neutralisation
it-IT	Italian (Italy)	Interferone.beta 1 Ab.Neut:Titr:Pt:Siero/Plasma:SemiQn:Neut Synonyms: anticorpo Interferone beta Plasma Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant Test di neutralizzazione Titolo
ko-KR	Korean (Korea, Republic Of)	인터페론.베타 1 항체:역가:검사시점:혈청/혈장:정량:중화
nl-NL	Dutch (Netherlands)	interferon.bèta 1 As.neutraliserend:titer:moment:serum of plasma:semikwantitatief:neutralisatietest Synonyms: antistof; antilichaam
pl-PL	Polish (Poland)	Interferon.beta 1 Ab.Neutralizujące:miano:punkt w czasie:surowica lub osocze:półilościowy:test neutralizacji Synonyms: IFN-beta Interferon beta 1;IFN beta 1 Przeciwciała do interferonu beta 1 Przeciwciała neutralizujące do interferonu 1 beta
pt-BR	Portuguese (Brazil)	Interferon.beta 1 Ac:Título:Pt:Sor/Plas:Qn:Teste de neutralização Synonyms: ; B-IFN1; INF-B1; B-IFN; Betaferon; B-IFN 1A+1B; INF-B; IFN; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Nt; NT; Neutralization test; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; B; I; Serology
zh-CN	Chinese (China)	干扰素.beta 1 抗体.中和:滴定度:时间点:血清/血浆:半定量型:中和试验 Synonyms: Ⅰ Ab;自身抗体 B B1-IFN Ab B1-IFN 抗体 B1-IFN;beta 1 干扰素;beta 1干扰素;INF-B1;β1 干扰素;β1干扰素;干扰素 beta 1;干扰素.β1;干扰素β1 beta 1 干扰素 Ab beta 1 干扰素抗体 beta 1干扰素 Ab beta 1干扰素抗体 beta 干扰素;B-IFN;B-IFN 1A+1B;INF-B;β干扰素;干扰素 beta;干扰素.β;干扰素β I IFN INF-B1 Ab INF-B1 抗体 β β1 干扰素 Ab β1 干扰素抗体 β1干扰素 Ab β1干扰素抗体中和试验;中和抗体;中和干扰素 beta 1 Ab 干扰素 beta 1 抗体干扰素.beta 1 Ab 干扰素.β1 Ab 干扰素.β1 抗体干扰素β1 Ab 干扰素β1 抗体效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数时刻;随机;随意;瞬间血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类血清或血浆贝塔

Example Units

Unit	Source
{titer}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.