31023-5

Myelin associated glycoprotein IgM Ab [Presence] in Serum by Immunoblot

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Part Description

LP18213-6 Myelin associated glycoprotein
Myelin associated glycoprotein (MAG) is a 100 kDa transmembrane glycoprotein found in the periaxonal membranes of Schwann cells and oligodendrocytes of myelin sheaths. Despite the fact that MAG is a known white matter inhibitor of axonal regeneration and as a receptor for IgM antibodies that demyelinates peripheral nerves, it has important roles that promote normal formation and maintenance of myelinated axons. There are two apparent functions of MAG which are to act as a ligand for an axonal receptor which maintains myelinated axons, and to act as an axonal signal receptor that promotes differentiation, maintenance, and survival of oligodendrocytes. MAG shares an epitope with other glyoconjugates that is the target protein in autoimmune peripheral neuropathy, that is associated with IgM gammopathy which causes the death of oligodendrocytes that is seen in multiple sclerosis. PMID: 17241126 Source: Regenstrief LOINC

Fully-Specified Name

Component: Myelin associated glycoprotein Ab.IgM
Property: PrThr
Time: Pt
System: Ser
Scale: Ord
Method: IB

Additional Names

Long Common Name: Myelin associated glycoprotein IgM Ab [Presence] in Serum by Immunoblot
Short Name: MAG IgM Ser Ql IB
Display Name: Myelin associated glycoprotein IgM IB Ql (S)
Consumer Name Alpha Get Info: Myelin associated glycoprotein IgM antibody, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.04
Last Updated: Version 2.73 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both
Common Test Rank Get Info: 7576

Member of these Groups Get Info

LOINC Group	Group Name
LG12245-3	Myelin associated glycoprotein Ab.IgM\|PrThr\|Pt\|ANYBldSerPl

Language Variants Get Info

Tag	Language	Translation
de-DE	German (Germany)	Myelin-assoziiertes Glycoprotein Ak.IgM:Nachweis oder Schwellenwert:Zeitpunkt:Serum:Ordinal:Immunoblot
el-GR	Greek (Greece)	Γλυκοπρωτεΐνη σχετιζόμενη με τη μυελίνη Αντισώματα IgM:PrThr:Pt:Ορός:Ord:IB Synonyms: PrThr Ανοσοσφαιρίνη M Γλυκοπρωτεΐνη σχετιζόμενη με τη μυελίνη Μυελίνη
es-AR	Spanish (Argentina)	[anticuerpo anti - ] glucoproteína asociada a la mielina [Ac].IgM [Inmunoglobulina M]:concentración arbitraria:punto en el tiempo:suero:ordinal:inmunotransferencia
es-ES	Spanish (Spain)	Glicoproteína asociada a la mielina IgM:PrThr:Punto temporal:Suero:Ord:Inmunoblot (IB)
es-MX	Spanish (Mexico)	Glicoproteína Ab.IgM asociada a mielina:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunotransferencia
fr-CA	French (Canada)	Glycoprotéine associée à la myéline, IgM:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoblot
fr-FR	French (France)	MAG anticorps IgM:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunoblot
fr-BE	French (Belgium)	Glycoprotéine associée à la myéline Anticorps. IgM:PrThr:Temps ponctuel:Sérum:Ordinal:Immunoblot Synonyms: Anticorps
it-IT	Italian (Italy)	Mielina, glicoproteina associata Ab.IgM:PrThr:Pt:Siero:Ord:IB Synonyms: Anticorpi IgM anticorpo Glicoproteina associata alla mielina Immunoblot (IB) Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
ko-KR	Korean (Korea, Republic Of)	말이집 관련 당단백질 항체.면역글로불린 M:임의농도:검사시점:혈청:순위척도:면역 탁본법
nl-NL	Dutch (Netherlands)	myeline-geassocieerd glycoproteïne As.IgM:aanwezigheid:moment:serum:ordinaal:immunoblotting Synonyms: antistof; antilichaam IB
pt-BR	Portuguese (Brazil)	Mielina associada a glicoproteína Ac.IgM:ACnc:Pt:Soro:Ord:Imunoblot Synonyms: ; MAG; Immune globulin M; Immunoglobulin M; Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; Western blot; WB; Immune blot; Immunobl; Blt; WBLOT; West blt; West blot; RIBA; Immunoblot; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Glycoprot; Glycoproteins; gG; GP; Assoc; Serology; MAGM
ru-RU	Russian (Russian Federation)	Миелин ассоциированный гликопротеин Ат.IgM:PrThr:ТчкВрм:Сыв:Пор:ИБ Synonyms: Антитело Иммуноблот (ИБ) Миелин-ассоциированный гликопротеин Порядковый Сыворотка Точка во времени;Момент
tr-TR	Turkish (Turkey)	Miyelinle ilişkili glikoprotein Ab.IgM:MevcEşik:Zmlı:Ser:Srl:IB Synonyms: Mevcut
zh-CN	Chinese (China)	髓磷脂相关糖蛋白抗体.IgM:存在情况或阈值:时间点:血清:序数型:免疫印迹法 Synonyms: Ab.IgM;IgM;抗体 IgM Ab;自身抗体 gp MAG Ab MAG Ab.IgM MAG 抗体 MAG 抗体.IgM MAG;髓磷脂相关糖蛋白（Myelin Associated Glycoprotein，MAG） MAGM 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫印迹;西部印迹法;Immunoblot;immunoblotting;IB 免疫球蛋白 M 关联的存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间有联系的相关的糖朊糖缀蛋白糖蛋白（Glycoprotein，gp，GP）糖蛋白类血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类醣蛋白骨磷脂;髓鞘质髓磷脂相关糖蛋白 Ab 髓磷脂相关糖蛋白 Ab.IgM 髓磷脂相关糖蛋白 IgM 髓磷脂相关糖蛋白 IgM（Myelin associated glycoprotein IgM，MAGM）

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