31496-3
Ganglioside GM1 Ab [Units/volume] in Serum
Active
Part Descriptions
LP36423-9 Ganglioside GM1
Gangliosides are a family of molecules that are present throughout the body but especially prevalent in cells of the nervous system. Specific gangliosides are named for the carbohydrate sequence they contain and have a unique distribution within the nervous system. The oligosaccharide groups on gangliosides act as cell surface markers that play a role in cellular recognition and cell-to-cell communication, and they also act as specific receptors for certain pituitary glycoprotein hormones and certain bacterial protein toxins such as cholera toxin.
Anti-ganglioside antibodies, primarily IgG, are present in the sera from approximately 60% of patients with Guillain-Barré syndrome (GBS), and antibodies against different gangliosides are associated with different forms of GBS.
1. Antibodies against GD1a/GD1b and GD1b/GT1b complexes have been found in patients with more severe GBS requiring mechanical ventilation;
2. Antibodies against GM1 or those against GalNAc-GD1a have been associated with acute motor axonal neuropathy;
3. Anti-GQ1b antibodies are specifically associated with a variant of GBS called Fisher syndrome, which is characterized by ophthalmoplegia and ataxia.
Detection of specific markers early in the course of GBS may help guide the plan of care. PMID: 21214559
Source: Regenstrief LOINC,
PMID: 2121455
LP38226-4 Ganglioside GM1 Ab
Ganglioside antibodies are associated with diverse peripheral neuropathies. Elevated antibody levels to ganglioside-monosialic acid (GM1) are associated with motor or sensorimotor neuropathies, particularly multifocal motor neuropathy. Anti-GM1 may occur as IgM (polyclonal or monoclonal) or IgG antibodies. These antibodies may also be found in patients with diverse connective tissue diseases as well as normal individuals.
Source: ARUP Laboratories,
GM1
LP222219-0 Ganglioside
A ganglioside molecule consists of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acid residues linked to the sugar chain. Molecules with one sialic acid residue are called monosialogangliosides (GM), those with two are called disialogangliosides (GD), and those with three are trisialogangliosides (GT). Gangliosides without any sialic acid residues are called asialogangliosides, while those that do not have a ceramide N-acyl group are called lysogangliosides. The number that typically is included at the end of the name indicates the order in which the molecule was discovered. For example, GM2 is a ganglioside with one sialic acid residue that was the second GM to be identified.
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Ganglioside GM1 Ab:
ACnc: Pt: Ser: Qn: - Long Common Name
- Ganglioside GM1 Ab [Units/volume] in Serum
- Short Name
- GM1 Gangl Ab Ser-aCnc
- Display Name
- Ganglioside GM1 Ab Qn (S)
- Consumer Name Alpha Get Info
- Ganglioside GM1 antibody, Blood
Part Model Get Info
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.07
- Last Updated
- Version 2.68 (MIN)
- Order vs. Observation
- Observation
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG12480-6 | Ganglioside GM1 Ab| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Gangliosid GM1 Ab: |
| el-GR | Greek (Greece) | Γαγγλιοσίδη GM1 Αντίσωμα: Synonyms: ACnc Pt Qn SERO Αντίσωμα Γαγγλιοσίδη Γαγγλιοσίδη GM1 Ορός |
| es-AR | Spanish (Argentina) | [anticuerpo anti - ] monosialogangliósido GM1 [Ac]: |
| es-ES | Spanish (Spain) | Gangliósido GM1 Anticuerpos: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Gangliósido GM1 Ab: |
| et-EE | Estonian (Estonia) | Gangliosiid GM1 antikehad: Synonyms: Juhuslik Kvantitatiivne Seerum |
| fr-CA | French (Canada) | Ganglioside GM1, Ac: |
| fr-FR | French (France) | Ganglioside GM1 Ac: |
| fr-BE | French (Belgium) | Ganglioside GM1 Ac: Synonyms: Anticorps |
| it-IT | Italian (Italy) | Ganglioside GM1 Ab: Synonyms: anticorpo Concentrazione Arbitraria Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
| ko-KR | Korean (Korea, Republic Of) | Monosialoganglioside GM1 Antibody: |
| nl-NL | Dutch (Netherlands) | ganglioside GM1 As: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Gangliozyd GM1 Ab: Synonyms: Przeciwciała do gangliozydu GM1 |
| pt-BR | Portuguese (Brazil) | Monosialogangliosídeo GM1 Ac: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Ганглиозид GM1 Ат: Synonyms: Антитело Количественный Произвольная концентрация Сыворотка Точка во времени; |
| tr-TR | Turkish (Turkey) | Gangliozid GM1 Ab: Synonyms: Ak |
| zh-CN | Chinese (China) | 神经节苷脂 GM1 抗体: Synonyms: Ab; |
Example Units
| Unit | Source |
|---|---|
| [arb'U]/mL | Example UCUM Units |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://