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Part Description

LP30736-0   Homocysteine cysteine disulfide
Homocystine is the double-bonded form of homocysteine, but it occurs only transiently before being converted to the harmless cystathionine via a vitamin B6-dependent enzyme. Homocystine and homocysteine-cysteine mixed disulfide account for >98% of total homocysteine in plasma from healthy individuals. PMID: 11592966 Oxidation of low-density lipoprotein (LDL) is thought to be a major factor in the pathophysiology of atherosclerosis. Elevated plasma homocysteine is an accepted risk factor for atherosclerosis, and may act through LDL oxidation, although this is controversial. However, the major thiol in plasma is cysteine, which is present at concentrations approximately 10 times greater than homocysteine; therefore homocystine in plasma is insignificant, and consequently homocystine is unlikely to influence LDL oxidation in vivo. PMID: 14732479 Increasing evidence supports a role for an elevation of homocysteine in schizophrenia. It has been demonstrated that neural tube defects are related to a genetic defect in homocysteine metabolism. Sufficient intake of folic acid is believed to reduce this risk by enhancing methylation of homocysteine and its conversion to methionine, thereby compensating for this genetic defect. Plasma homocysteine levels are elevated when folate levels are in the lower half of the normal range. PMID: 16143442 Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database,

LOINC Names Get Info

Fully-Specified Name
Homocysteine cysteine disulfide:SCnc:Pt:Ser/Plas:Qn:
Long Common Name
Homocysteine cysteine disulfide [Moles/volume] in Serum or Plasma
Short Name
Hycs-Cys diS SerPl-sCnc
Display Name
Homocysteine cysteine disulfide [Moles/Vol]
Consumer Name Alpha Get Info
Homocysteine cysteine disulfide, Blood

Part Model Get Info

  • Component
    Homocysteine cysteine disulfide
    LP30736-0
    • Analyte
      Homocysteine cysteine disulfide
      LP30736-0
      • Component Numerator
        Homocysteine cysteine disulfide
        LP30736-0
        • Component Numerator Core
          Homocysteine cysteine disulfide
          LP30736-0
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    SCnc
    LP6860-3
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.09
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Both
Common Test Rank Get Info
19371

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Homocystein-cystein-disulfid:Látková koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
el-GRGreek (Greece)Δισουλφιδικός δεσμός κυστεΐνης-ομοκυστεΐνης:SCnc:Pt:Ορός/Πλάσμα:Qn:
Synonyms: CHEM Pt Qn SCnc Δισουλφιδικός δεσμός κυστεΐνης-ομοκυστεΐνης Κυστεΐνη Ομοκυστεΐνη Ορός Ορός/Πλάσμα Πλάσμα
es-ARSpanish (Argentina)disulfuro de cisteína homocisteína:concentración de sustancia:punto en el tiempo:suero/plasma:cuantitativo:
es-ESSpanish (Spain)Homocisteína cisteína disulfuro:Concentración de sustancia:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Disulfuro de cisteína de homocisteína:Concentración de sustancias:Punto temporal:Suero o Plasma:Cuantitativo:
fr-CAFrench (Canada)Bisulfure de cystéine homocystéine:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FRFrench (France)Homocystéine cystéine disulfide:Moles/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BEFrench (Belgium)Bisulfure de cystéine homocystéine:Concentration de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-ITItalian (Italy)Omocisteina cisteina, disolfuro:SCnc:Pt:Siero/Plasma:Qn:
Synonyms: Chimica Concentrazione di Sostanza Disolfuro omocisteina cisteina Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KRKorean (Korea, Republic Of)호모시스테인 시스테인 이황화물:물질농도:검사시점:혈청/혈장:정량:
nl-NLDutch (Netherlands)homocysteïne cysteïne disulfide:mol/volume:moment:serum of plasma:kwantitatief:
pl-PLPolish (Poland)Homocysteina cysteina disiarczek:stężenie molowe:punkt w czasie:surowica lub osocze:ilościowy:
Synonyms: Disiarczek homocysteiny-cysteiny;Wiązanie disiarczkowe cysteiny i homocysteiny
pt-BRPortuguese (Brazil)Homocisteina dissulfeto de cisteina:SCnc:Pt:Sor/Plas:Qn:
Synonyms: ; Hycs-Cys diS; Hycs-Cys Disulfide; Hcys; Hcyst; HCY; Cys; Substance concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Chemistry
ru-RURussian (Russian Federation)Гомоцистеин цистеин дисульфид:МолКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Молярность;Молярная объёмная концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TRTurkish (Turkey)Homosistein sistein disülfür:SubKons:Zmlı:Ser/Plaz:Kant:
zh-CNChinese (China)同型半胱氨酸-半胱氨酸二硫化物:物质的量浓度:时间点:血清/血浆:定量型:
Synonyms: Cys;巯基丙氨酸 HCY;Hcys;Hcyst;巯基丁氨酸;高半胱氨酸 Hcys-Cys diS;Hcys-Cys 二硫化物;巯基丁氨酸-巯基丙氨酸二硫化物 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 血清或血浆

Example Units

UnitSource
umol/LExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=32615-7