32629-8
Protein.monoclonal/Protein.total in Specimen by Immunofixation
Active
Term Description
When one or more monoclonal (M) bands are found, laboratories will often label them as M, Band 2, Band 3, etc. This term is used to report the percent of that part of M.
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Part Descriptions
LP30793-1 Protein.monoclonal
A monoclonal band (M-spike, monoclonal protein isotype) is often found in patients with monoclonal gammopathies. Following protein electrophoresis, immunofixation is used to identify the immunoglobulin heavy chain and/or light chain. Monoclonal peaks greater than 3 g/dL and IgG or IgA are seen in patients with Multiple Myeloma (MM). A monoclonal peak greater than 3 g/dL and IgM is seen in patients with macroglobulinemia. An alternate methodology for identifying the monoclonal protein isotype is MALDI-TOF, in which known information regarding the unique mass of each isotype is used to determine and quantify the isotype present in the patient sample based on the mass spectra generated from the sample.
Source: Regenstrief LOINC
LP32144-5 Protein.total
Serum total protein, also called plasma total protein or total protein, is a biochemical test for measuring the total amount of protein in blood plasma or serum.
Protein in the plasma is made up of albumin and globulin. The globulin in turn is made up of α1, α2, β, and γ globulins. These fractions can be quantitated using protein electrophoresis, but the total protein test is a faster and cheaper test that estimates the total of all fractions together. The traditional method for measuring total protein uses the biuret reagent, but other chemical methods such as Kjeldahl method, dye-binding and refractometry are now available. The measurement is usually performed on automated analysers along with other laboratory tests.
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Source: Wikipedia
, Total protein
LP6336-4 Immunofixation
Plasma or concentrated urine is deposited on a gel. With an electrical current the proteins are sorted in function of their size, after which antigens for each targeted type of immunoglobulin are deposited on the gel. Thus more or less narrow bands appear on the gel, marking the location of the various immunoglobulines.
Immunofixation tends to replace protein electrophoresis because:
• it is faster (results within three hours);
• it is somewhat more sensitive. Immunofixation may reveal an immunoglobulin missed out by protein electrophoresis, especially at low concentrations (less than 1 gram/litre);
• it can be partially automated and can be used in more laboratories;
• it is more easily read and interpreted.
Immunofixation is however only sensitive to immunoglobulins and is more expensive than protein electrophoresis.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia
, Immunofixation
Fully-Specified Name
- Component
- Protein.monoclonal/Protein.total
- Property
- MFr
- Time
- Pt
- System
- XXX
- Scale
- Qn
- Method
- Immunofixation
Additional Names
- Long Common Name
- Protein.monoclonal/Protein.total in Specimen by Immunofixation
- Short Name
- M Protein MFr Spec IFE
- Display Name
- Protein.monoclonal Immunofixation (Specimen) [Mass fraction]
- Consumer Name Alpha Get Info
- Protein.monoclonal, Specimen
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.09
- Last Updated
- Version 2.70 (MIN)
- Order vs. Observation
- Observation
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Πρωτεΐνη.μονοκλωνική/Πρωτεΐνη.ολική: Synonyms: MFr Πρωτεΐνη Πρωτεΐνη.μονοκλωνική |
| es-AR | Spanish (Argentina) | proteína.monoclonal/proteína.total: |
| es-ES | Spanish (Spain) | Proteinas monoclonales/Proteinas totales: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Proteína.monoclonal / Proteína.total: |
| et-EE | Estonian (Estonia) | Valk.monoklonaalne/valk.üld: Synonyms: Juhuslik Kvantitatiivne Täpsustamata materjal |
| fr-CA | French (Canada) | Protéines.monoclonales/Protéines.totales: |
| fr-FR | French (France) | Immunoglobuline monoclonale/protéines totales: |
| fr-BE | French (Belgium) | Protéines.monoclonales/Protéines.totales: |
| it-IT | Italian (Italy) | Proteina.monoclonale/Proteina.totale: Synonyms: Chimica Frazione di massa Punto nel tempo (episodio) |
| ko-KR | Korean (Korea, Republic Of) | 단클론 단백/총단백: |
| nl-NL | Dutch (Netherlands) | eiwit.monoclonale/totaal eiwit: Synonyms: proteïne.totaal |
| pl-PL | Polish (Poland) | Białko monoklonalne/białko całkowite: |
| pt-BR | Portuguese (Brazil) | Proteína.monoclonal/Proteína.total: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Протеин.моноклональный/Протеин.общий: Synonyms: Белок Белок.общий Количественный Массовая доля Точка во времени; |
| tr-TR | Turkish (Turkey) | Protein.monoklonal/Protein.total: |
| zh-CN | Chinese (China) | 蛋白质.单克隆型/蛋白质.总计: Synonyms: IFE; |
Example Units
| Unit | Source |
|---|---|
| % | Example UCUM Units |
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