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Part Description

LP28780-2   Islet cell 512
Islet cell antigen (ICA) 512 is a receptor-tyrosine phosphatase-like protein associated with the secretory granules of neuroendocrine cells. ICA-512 is also known as protein tyrosine phosphatase-IA2 (PTP-IA2) or tyrosine phosphatase (IA2). It is an autoantigen of type 1 diabetes. This is NOT the same as pancreatic islet cell. Studies on type-1 diabetic patient's relatives found that the development of one or more islet autoantibodies (including IA-2 antibody) was an early indicator of the relatives' progression to type-1 diabetes. Autoantibody profiles identifying patients destined to develop type-1 diabetes are usually detectable before age three. One study found that for relatives seropositive for IA-2 antibody, the likelihood of developing type-1 diabetes mellitus within five-years was 65.3%. Some type-1 diabetic patients are originally diagnosed as having type-2 diabetes due to symptom onset in adulthood, societal obesity, and initial insulin-independence. Detection of one or more islet auto-antibodies (including IA-2) may be used to distinguish these patients with "latent autoimmune diabetes" from type-2 diabetics. Source: Regenstrief Institute

LOINC Names Get Info

Fully-Specified Name
Islet cell 512 Ab:Titr:Pt:Ser:SemiQn:
Long Common Name
Islet cell 512 Ab [Titer] in Serum
Short Name
Islet Cell512 Ab Titr Ser
Display Name
Islet cell 512 Ab (S) [Titer]
Consumer Name Alpha Get Info
Islet cell 512 antibody, Blood

Part Model Get Info

  • Component
    Islet cell 512 Ab
    LP38717-2
    • Analyte
      Islet cell 512 Ab
      LP38717-2
      • Component Numerator
        Islet cell 512 Ab
        LP38717-2
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Titr
    LP6881-9
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    SemiQn
    LP436123-6
  • Method
    NULL
     

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.09
Last Updated
Version 2.75 (MAJ)
Order vs. Observation
Both
Common Test Rank Get Info
19700

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Buňka ostrůvků 512 Ab:Arbitrární koncentrace (titr):Časový bod:Sérum:Semikvantitativní:
el-GRGreek (Greece)Νησιδιακό κύτταρο 512 Αντίσωμα:Titr:Pt:Ορός:Ημιποσοτική:
Synonyms: Pt SERO Titr Αντίσωμα Ημιποσοτική Νησιδιακό κύτταρο 512 Ορός
es-ARSpanish (Argentina)anticuerpo contra célula de islote 512:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:
es-ESSpanish (Spain)Célula de los islotes 512 Anticuerpos:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:
Synonyms: Semicuantitativo
es-MXSpanish (Mexico)Celda de islotes 512 Ab:Título:Punto temporal:Suero:Cuantitativo:
fr-CAFrench (Canada)ICA 512 d'îlots de Langerhans, Ac:Titre:Temps ponctuel:Sérum:SemiQn:
fr-FRFrench (France)Cellules îlots 512 Ac:Titre:Ponctuel:Sérum:Semi-Quantitatif:
it-ITItalian (Italy)Isola 512 cellula Ab:Titr:Pt:Siero:SemiQn:
Synonyms: anticorpo Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant Titolo
ko-KRKorean (Korea, Republic Of)섬 세포 512 항체:역가:검사시점:혈청:정량:
nl-NLDutch (Netherlands)islet antigeen-2 As:titer:moment:serum:semikwantitatief:
Synonyms: antistof; antilichaam IA-2
pl-PLPolish (Poland)Komórki wyspowe 512 Ab:miano:punkt w czasie:surowica:półilościowy:
Synonyms: Antygen 512 komórek wyspowych
pt-BRPortuguese (Brazil)Ilhota célula 512 Ac:Título:Pt:Soro:Qn:
Synonyms: ICA; ICA512; Islet Cell512; IA-2; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Serology
zh-CNChinese (China)岛细胞 512 抗体:滴定度:时间点:血清:半定量型:
Synonyms: Ab;自身抗体 IA-2;ICA;ICA512;小岛细胞 512;小岛细胞 512（Islet cell 512）;岛细胞 512（Islet cell 512）;这里的岛细胞（ Islet Cell）并不等同于胰岛细胞（ Pancreatic Islet Cell） ICA ICA512 小岛细胞 512 Ab 小岛细胞 512 抗体 岛细胞 512 Ab 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

UnitSource
{titer}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=32636-3