Version 2.78

Part Descriptions

LP30829-3   Interleukin 8
Interleukin-8 (IL-8) is a chemokine produced by macrophages and other cell types such as epithelial cells. It is also synthesized by endothelial cells, which store IL-8 in their storage vesicles, the Weibel-Palade bodies. In humans, the interleukin-8 protein is encoded by the IL8 gene.

Interleukin-8 is often associated with inflammation. As an example, it has been cited as a proinflammatory mediator in gingivitis and psoriasis. The fact that Interleukin-8 secretion is increased by oxidant stress and conversely, Interleukin-8, by causing recruitment of inflammatory cells induces a further increase in oxidant stress mediators, makes it a key parameter in localized inflammation.

If a pregnant mother has high levels of interleukin-8, there is an increased risk of schizophrenia in her offspring. High levels of Interleukin 8 have been shown to reduce the likelihood of positive responses to antipsychotic medication in schizophrenia. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

LP30829-3   Interleukin 8
The Interleukins belong to the family termed cytokines. They are peptides used by immune and inflammatory cells to communicate and control cell operations. The cytokines have some similar actions to the Growth Factors but Growth Factors regulate proliferation of non-immune cells. Interleukin 8 is a 6,000 - 8000 molecular weight glycoprotein produced primarily by macrophages and monocytes. Its primary target cells are neutrophils. Interleukin 8 is a chemotactic agent for monocytes and neutrophils. Interleukin 8 causes oxygen radical and enzyme release by neutrophils and mobilizes products into circulation. Interleukin 8 is stimulated by Interleukin 1 and Tumor Necrosis Factor. Source: Inter Science Institute, Inter Science Institute

Fully-Specified Name

Component
Interleukin 8
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Il8 SerPl-mCnc
Display Name
Interleukin 8 [Mass/Vol]
Consumer Name Alpha Get Info
Interleukin 8, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.09
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
6992

Member of these Panels

LOINC Long Common Name
82335-1 Cytokines panel - Serum or Plasma

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: Interleukin-8
de-DE German (Germany) Interleukin-8:Massenkonzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:
es-AR Spanish (Argentina) interleucina 8:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-ES Spanish (Spain) Interleucina 8:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Interleucina 8:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE Estonian (Estonia) Interleukiin 8:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA French (Canada) Interleukine 8:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR French (France) Interleukine-8:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE French (Belgium) Interleukine 8:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
Synonyms: IL 8
it-IT Italian (Italy) Interleuchina 8:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Chimica Concentrazione di Massa Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR Korean (Korea, Republic Of) 인터루킨 8:질량농도:검사시점:혈청/혈장:정량:
nl-NL Dutch (Netherlands) interleukine 8:massa/volume:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) Interleucina 8:MCnc:Pt:Sor/Plas:Qn:
Synonyms: ; Il8; IL-8; Chemotactic Factor, Macrophage-Derived; Chemotactic Factor, Neutrophil, Monocyte-Derived; Leukocyte Adhesion Inhibitor; Neutrophil-Activating Peptide, Lymphocyte-Derived; Neutrophil-Activating Peptide, Monocyte-Derived; Neutrophil-Activating Peptides, Fibroblast-Derived; Anionic Neutrophil-Activating Peptide; Chemotactic Factor, Neutrophil; Neutrophil Activation Factor; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; IL; Chemistry
ru-RU Russian (Russian Federation) Интерлейкин 8:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) İnterlökin 8:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 白细胞介素 8:质量浓度:时间点:血清/血浆:定量型:
Synonyms: IL Il8;IL-8;嗜中性粒细胞激活因子;嗜中性粒细胞激活肽, 单核细胞源性;嗜中性粒细胞激活肽, 成纤维细胞细胞源性;嗜中性粒细胞激活肽, 淋巴细胞源性;白介素 8;白介素-8;白细胞介素-8;白细胞粘附抑制剂;白细胞黏附抑制剂;趋化因子, 嗜中性粒细胞;趋化因子, 嗜中性粒细胞, 单核细胞源性;趋化因子, 巨噬细胞源性;阴离子嗜中性粒细胞激活肽 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 水平;浓度;质量浓度(单位体积) 白介 白介素 白细胞介素（Interleukin，白介素，IL） 血清或血浆

Example Units

Unit Source
pg/mL Example UCUM Units
pg/mL REGENSTRIEF

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=33211-4