33253-6

Nuclear Ab [Titer] in Serum by Hep2 substrate

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Part Descriptions

LP16670-9   Nuclear
The nucleus of a cell contains the body's genetic material. It is the site of transcriptional regulation, RNA processing and DNA synthesis and transcription.
PMID: 24563360 Source: Regenstrief LOINC

LP20752-9   Nuclear Ab
Anti-nuclear antibodies (ANAs), also known as anti-nuclear factor or ANF, are auto-antibodies directed against contents of the cell nucleus. They are present in low numbers in the general population but higher than normal amounts in autoimmune diseases, including lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, scleroderma, and autoimmune hepatitis. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Anti-nuclear antibodies

LP20752-9   Nuclear Ab
Anti-nuclear antibodies (ANAs, also known as anti-nuclear factor or ANF) are autoantibodies directed against contents of the cell nucleus. They are present in higher than normal numbers in autoimmune disease. The ANA test measures the pattern and amount of autoantibody which can attack the body's tissues as if they were foreign material. Autoantibodies are present in low titers in the general population, but in about 5% of the population, their concentration is increased, and about half of this 5% have an autoimmune disease.

The presence of ANA is indicative of lupus erythematosus (present in 80-90% of cases), though they also appear in some other auto-immune diseases such as[citation needed] Sjögren's syndrome (60%), rheumatoid arthritis (30-40%), autoimmune hepatitis, scleroderma and polymyositis & dermatomyositis (30%), and various non-rheumatological conditions associated with tissue damage. Other conditions with high ANA titre include Addison disease, Idiopathic thrombocytopenic purpura (ITP), Hashimoto's, Autoimmune hemolytic anemia, Type I diabetes mellitus, Mixed connective tissue disorder. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Fully-Specified Name

Component

Nuclear Ab

Property

Titr

Time

Pt

System

Ser

Scale

SemiQn

Method

Hep2 substrate

Additional Names

Short Name

ANA Titr Ser HEp2 subst

Display Name

Nuclear Ab Hep2 substrate (S) [Titer]

Consumer Name Alpha Get Info

Nuclear antibody, Blood

Basic Attributes

Class

SERO

Type

Laboratory

First Released

Version 2.09

Last Updated

Version 2.75

Order vs. Observation

Both

Common Test Rank Get Info

3654

Member of these Groups Get Info

Language Variants Get Info

Related Names

• ABS
• Aby
• ANA
• ANF
• Antby
• Anti
• Antibodies
• Antibody
• Antinuclear antibody
• Autoantibodies
• Autoantibody
• Dilution factor
• Dilution Factor (Titer)
• NA
• Nuc
• Point in time
• Random
• Serology
• Serum
• SmQn
• SR
• Titer
• Titered
• Titre
• Ttr

Example Units

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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.