33636-2
IgA.secretory [Units/volume] in Saliva (oral fluid)
Active
Part Descriptions
LP18167-4 IgA.secretory
Secretory IgA is a dimer with a special secretory component that protects it from proteolytic digestion. IgA protects the GI tract and other endothelial surfaces from infection IgA does not cross the placenta (for practical purposes)
Source: Regenstrief Institute
LP18167-4 IgA.secretory
IgA has two subclasses (IgA1 and IgA2) and can exist in a dimeric form called secretory IgA (sIgA). In its secretory form, IgA is the main immunoglobulin found in mucous secretions, including tears, saliva, colostrum and secretions from the genitourinary tract, gastrointestinal tract, prostate and respiratory epithelium. It is also found in small amounts in blood. The secretory component of sIgA protects the immunoglobulin from being degraded by proteolytic enzymes, thus sIgA can survive in the harsh gastrointestinal tract environment and provide protection against microbes that multiply in body secretions.
Decreased or absent IgA, termed selective IgA deficiency, can be a clinically significant immunodeficiency.
Neisseria gonorrhœae (which causes gonorrhea), Streptococcus pneumoniae, and Haemophilus influenzae type B all releases a protease which destroys IgA.
IgA nephropathy is caused by IgA deposits in the kidneys. It is not yet known why IgA deposits occur in this chronic disease. Some theories suggest an abnormality of the immune system results in these deposits.
Celiac disease involves IgA pathology due to the presence of IgA antiendomysial antibodies.
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Source: Wikipedia,
Wikipedia
LP7565-7 Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- IgA.secretory:
ACnc: Pt: Saliva: Qn: - Long Common Name
- IgA.secretory [Units/volume] in Saliva (oral fluid)
- Short Name
- SIgA Sal-aCnc
- Display Name
- IgA.secretory Qn (Sal)
- Consumer Name Alpha Get Info
- IgA.secretory, Saliva
Part Model Get Info
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.09
- Last Updated
- Version 2.70 (MIN)
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| ar-JO | Arabic (Jordan) | أضداد الغلوبولين المناعي نمط A الإفرازي في اللعاب " السائل الفموي " ( بتقنية الوحدات / الحجم ) |
| cs-CZ | Czech (Czechia) | IgA.sekreční: |
| el-GR | Greek (Greece) | IgA.εκκριτική: Synonyms: ACnc CHEM IgA.εκκριτική Pt Qn Ανοσοσφαιρίνη Α Σίελος |
| es-AR | Spanish (Argentina) | IgA [Inmunoglobulina A]. secretoria: |
| es-ES | Spanish (Spain) | IgA secretora: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Secretario de IgA.: |
| et-EE | Estonian (Estonia) | IgA.sekretoorne: Synonyms: Immuunglobuliin A Juhuslik Kvantitatiivne Sülg |
| fr-CA | French (Canada) | IgA.sécrétoire: |
| fr-FR | French (France) | Immunoglobuline A secrétoire: |
| fr-BE | French (Belgium) | IgA.sécrétoire: Synonyms: sIgA |
| it-IT | Italian (Italy) | IgA.secretorie: Synonyms: Chimica Concentrazione Arbitraria Punto nel tempo (episodio) |
| ko-KR | Korean (Korea, Republic Of) | 분비형면역글로불린 A: |
| nl-NL | Dutch (Netherlands) | IgA.secretoir: |
| pl-PL | Polish (Poland) | Ig A.wydzielncza: Synonyms: Immunoglobulina A Wydzielnicza immunoglobulina A |
| pt-BR | Portuguese (Brazil) | IgA.secretoria: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | IgA.секреторный: Synonyms: Количественный Произвольная концентрация Точка во времени; |
| tr-TR | Turkish (Turkey) | IgA.sekretuvar: |
| zh-CN | Chinese (China) | IgA.分泌型: Synonyms: SIgA; |
Example Units
| Unit | Source |
|---|---|
| [arb'U]/mL | Example UCUM Units |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://