Version 2.80

Part Descriptions

LP30793-1   Protein.monoclonal
A monoclonal band (M-spike, monoclonal protein isotype) is often found in patients with monoclonal gammopathies. Following protein electrophoresis, immunofixation is used to identify the immunoglobulin heavy chain and/or light chain. Monoclonal peaks greater than 3 g/dL and IgG or IgA are seen in patients with Multiple Myeloma (MM). A monoclonal peak greater than 3 g/dL and IgM is seen in patients with macroglobulinemia. An alternate methodology for identifying the monoclonal protein isotype is MALDI-TOF, in which known information regarding the unique mass of each isotype is used to determine and quantify the isotype present in the patient sample based on the mass spectra generated from the sample. Source: Regenstrief LOINC

LP6336-4   Immunofixation
Plasma or concentrated urine is deposited on a gel. With an electrical current the proteins are sorted in function of their size, after which antigens for each targeted type of immunoglobulin are deposited on the gel. Thus more or less narrow bands appear on the gel, marking the location of the various immunoglobulines.
Immunofixation tends to replace protein electrophoresis because:

• it is faster (results within three hours);
• it is somewhat more sensitive. Immunofixation may reveal an immunoglobulin missed out by protein electrophoresis, especially at low concentrations (less than 1 gram/litre);
• it can be partially automated and can be used in more laboratories;
• it is more easily read and interpreted.

Immunofixation is however only sensitive to immunoglobulins and is more expensive than protein electrophoresis. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Immunofixation

Fully-Specified Name

Component
Protein.monoclonal
Property
MCnc
Time
Pt
System
XXX
Scale
Qn
Method
Immunofixation

Additional Names

Long Common Name
Protein.monoclonal [Mass/volume] in Specimen by Immunofixation
Short Name
M Protein Spec IFE-mCnc
Display Name
Protein.monoclonal Immunofixation (Specimen) [Mass/Vol]
Consumer Name Alpha Get Info
Protein.monoclonal, Specimen

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.09
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Observation
Common Test Rank Get Info
6260

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Πρωτεΐνη.μονοκλωνική:MCnc:Pt:XXX:Qn:Ανοσοκαθήλωση
Synonyms: MCnc Πρωτεΐνη Πρωτεΐνη.μονοκλωνική
es-AR Spanish (Argentina) proteína.monoclonal:concentración de masa:punto en el tiempo:XXX:cuantitativo:inmunofijación
es-ES Spanish (Spain) Proteinas monoclonales:Concentración de masa:Punto temporal:XXX:Qn:Inmunofijación
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Proteína monoclonal:Concentración de masa:Punto temporal:XXX:Cuantitativo:Inmunofijación
et-EE Estonian (Estonia) Valk.monoklonaalne:MCnc:Pt:XXX:Qn:Immuunfiksatsioon
Synonyms: Juhuslik Kvantitatiivne Täpsustamata materjal
fr-CA French (Canada) Protéines.monoclonales:Concentration de masse:Temps ponctuel:XXX:Quantitatif:Immunofixation
fr-FR French (France) Immunoglobuline monoclonale:Masse/Volume:Ponctuel:Milieux divers:Numérique:Immunofixation
fr-BE French (Belgium) Protéines.monoclonales:Concentration de masse:Temps ponctuel:XXX:Quantitatif:Immunofixation
it-IT Italian (Italy) Proteina.monoclonale:MCnc:Pt:XXX:Qn:Immunofissazione
Synonyms: Chimica Concentrazione di Massa Punto nel tempo (episodio)
ko-KR Korean (Korea, Republic Of) 단클론 단백:질량농도:검사시점:XXX:정량:면역고정
nl-NL Dutch (Netherlands) eiwit.monoclonale:massa/volume:moment:XXX:kwantitatief:immunofixatie
pl-PL Polish (Poland) Białko monoklonalne:stężenie masowe:punkt w czasie:XXX:ilościowy:immunofiksacja
pt-BR Portuguese (Brazil) Proteína.monoclonal:MCnc:Pt:XXX:Qn:Imunofixação
Synonyms: ; M Protein; M-spike; M-band; Monoclonal band; Monoclonal spike; M-protein; Para protein; Paraprotein; Prot; PR; Mass concentration; Level; Point in time; Random; Misc; Miscellaneous; Unspecified; Other; Quantitative; QNT; Quant; Quan; IFE; Ifix; Immunofixation electrophoresis; Chemistry
ru-RU Russian (Russian Federation) Протеин.моноклональный:МассКонц:ТчкВрм:XXX:Колич:Иммунофиксация
Synonyms: Белок Количественный Массовая концентрация Точка во времени;Момент
tr-TR Turkish (Turkey) Protein.monoklonal:KütlKons:Zmlı:XXX:Kant:İmmünfiksasyon
zh-CN Chinese (China) 蛋白质.单克隆型:质量浓度:时间点:XXX:定量型:免疫固定电泳分析法
Synonyms: IFE;Ifix;免疫固定法;免疫固定电泳（Immunofixation electrophoresis，IFE）;免疫固定电泳法 M 区带;M 峰;M 带;M 蛋白;副蛋白;单克隆区带;单克隆型蛋白质;单克隆型蛋白质区带;单克隆峰;单克隆性蛋白质;单克隆性蛋白质区带;单克隆蛋白质区带;异常蛋白;病变蛋白;蛋白质.单克隆 PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 水平;浓度;质量浓度(单位体积)

Example Units

Unit Source
ug/uL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=33879-8