Version 2.77

Part Descriptions

LP29176-2   Cyclic citrullinated peptide
Citrullinated peptide (CCP) is a naturally occurring protein that is produced during the metabolism of ornithine to arginine. CCP proteins are found in synovial tissue of patients with rheumatoid arthritis (RA). High levels of antibodies to CCP have a strong association with RA and are predictive of an aggressive and destructive disease outcome. CCP antibody tests can help diagnose RA when the rheumatoid factor (RF) is negative or below 50 IU/mL.(Pagana, Kathleen Deska, and Timothy James Pagana. Mosby's Manual of Diagnostic and Laboratory Tests. St. Louis, MO: Mosby/Elsevier, 2014. Print.) .) IgA to CCP is more elevated in patients with RA than levels found in healthy individuals or those with other rheumatic diseases. PMID: 18565246 Source: Regenstrief LOINC

LP37860-1   Cyclic citrullinated peptide Ab.IgG
Citrulline is a non-standard amino acid that can be incorporated into proteins only by modification of arginine during a variety of biologic processes including inflammation. Several citrullinated proteins have been demonstrated in the RA synovium. Rheumatoid arthritis (RA) is an inflammatory autoimmune disease with a prevalence of 0.3 to 1% worldwide and leads to progressive joint erosion and disability if not treated early. Identifying citrullinated epitopes targets led to first and then second generation anti-cyclic citrullinated peptide (anti-CCP) antibody assays. These anti-CCP antibodies are important diagnostic and prognostic markers for rheumatoid arthritis (RA) as they: 1) may be more sensitive than RF (rheumatoid factor) in early and established disease, 2) may be a marker of erosive disease, and 3) may be found in healthy patients years prior to clinical onset, and 4) may predict development of undifferentiated arthritis into RA. PMID: 19427413 PMID: 17558653 Source: Regenstrief LOINC, PMID: 19427413

Fully-Specified Name

Component
Cyclic citrullinated peptide Ab.IgG
Property
ACnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
cCP IgG SerPl-aCnc
Display Name
Cyclic citrullinated peptide IgG Qn
Consumer Name Alpha Get Info
Cyclic citrullinated peptide IgG antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.09
Last Updated
Version 2.73
Change Reason
Changing system from ser to reflect updates to procedure.
Order vs. Observation
Both
Common Test Rank Get Info
713

Member of these Panels

LOINC Long Common Name
46437-0 Rheumatoid Factor and Cyclic Citrullinated Peptide IgG panel [Units/volume] - Serum

Member of these Groups Get Info

LOINC Group Group Name
LG51009-5 Cyclic citrullinated peptide Ab.IgG|ACnc|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Κυκλικό κιτρουλλινιωμένο πεπτίδιο IgG ανοσοσφαιρίνη:Αυθαίρετη συγκέντρωση:Χρονική στιγμή:Ορός/Πλάσμα:Ποσοτική:
Synonyms: Ab IgG
es-AR Spanish (Argentina) anticuerpo contra péptido cíclico con citrulina.inmunoglobulina G:concentración arbitraria:punto en el tiempo:suero:cuantitativo:
es-ES Spanish (Spain) Peptido cíclico citrulinado IgG:Concentración arbitraria:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Péptido cíclico citrulinado Ab.IgG:Concentración arbitraria:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE Estonian (Estonia) Tsükliline tsitrulleeritud peptiid antikehad.IgG:Acnc:Pt:S/P:Qn:
Synonyms: Immuunglobuliin G Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA French (Canada) Peptide citrulliné cyclique , IgG:Concentration arbitraire:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR French (France) Peptide cyclique citrulliné anticorps IgG:Arbitraire/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE French (Belgium) Peptide citrulliné cyclique Anticorps. IgG:Concentration arbitraire:Temps ponctuel:Sérum/Plasma:Quantitatif:
Synonyms: Anticorps CCP
it-IT Italian (Italy) Peptide ciclico citrullinato Ab.IgG:ACnc:Pt:Siero/Plasma:Qn:
Synonyms: anticorpi IgG anticorpo CCP Concentrazione Arbitraria Plasma Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant
ko-KR Korean (Korea, Republic Of) Cyclic citrullinated peptide Antibody.immunoglobulin G:임의농도:검사시점:혈청:정량:
nl-NL Dutch (Netherlands) cyclisch citrulline-peptide As.IgG:eenheid/volume:moment:serum of plasma:kwantitatief:
Synonyms: antistof; antilichaam
pt-BR Portuguese (Brazil) Peptídeo Cíclico Citrulinado Ac.IgG:ACnc:Pt:Soro:Qn:
Synonyms: Immune globulin G; Immunoglobulin G; cCP; Cyclic Citrulinated Peptide; CCP3; Arbitrary concentration; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Pept; Serology
ru-RU Russian (Russian Federation) Циклический цитруллинизированный пептид Ат.IgG:ПроизвКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Антитело Количественный Плазма Произвольная концентрация Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Siklik sitrülline peptid Ab.IgG:SçKons:Zmlı:Ser/Plaz:Kant:
Synonyms: Ak Ak.IgG
uk-UA Ukrainian (Ukraine) Циклічний цитруліновий пептид, Антитіла.IgG:Довільна Концентрація:МоментЧасу:Сироватка/Плазма:Кількісно:
Synonyms: ABS; Aby; Antby; Anti; Antibodies; Antibody; Anti-CCP; Arbitrary concentration; Autoantibodies; Autoantibody; cCP; CCP3; Cyclic Citrulinated Peptide; Immune globulin G; Immunoglobulin G; Pept; Pl; Plasma; Plsm; Point in time; QNT; Quan; Quant; Quantitative; Random; Rheum; Rheumatoid arthritis; Rheumatology; Serology; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR; UniversalLabOrders
zh-CN Chinese (China) 环瓜氨酸肽 抗体.IgG:任意型浓度:时间点:血清/血浆:定量型:
Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 cCP;CCP3;环瓜氨酸肽;Cyclic Citrullinated Peptide 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 免疫球蛋白 G 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 抗环瓜氨酸肽 抗环瓜氨酸肽抗体 时刻;随机;随意;瞬间 环瓜氨酸肽 Ab 环瓜氨酸肽 Ab.IgG 环瓜氨酸肽 IgG 缩氨酸 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 血清或血浆

Example Units

Unit Source
units REGENSTRIEF
units/mL REGENSTRIEF
[arb'U]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=33935-8