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Part Descriptions

LP207365-0   Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP6416-4   Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Clostridioides difficile toxin Ab.Neut:Titr:Pt:Ser:SemiQn:Neut
Long Common Name
Clostridioides difficile toxin neutralizing antibody [Titer] in Serum by Neutralization test
Short Name
C diff Tox NAb Titr Ser Nt
Display Name
C. difficile toxin neut ab Neut test (S) [Titer]
Consumer Name Alpha Get Info
Clostridioides difficile toxin neutralizing antibody, Blood

Part Model Get Info

  • Component
    Clostridioides difficile toxin Ab.Neut
    LP430340-2
    • Analyte
      Clostridioides difficile toxin Ab.Neut
      LP430340-2
      • Component Numerator
        Clostridioides difficile toxin Ab.Neut
        LP430340-2
        • Component Numerator Core
          Clostridioides difficile toxin
          LP31758-3
        • Component Numerator Core Suffix
          Ab.Neut
          LP207365-0
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Titr
    LP6881-9
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    SemiQn
    LP436123-6
  • Method
    Neut
    LP6416-4

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.09
Last Updated
Version 2.75 (MAJ)
Change Reason
Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.; Previous Releases: Updated genus name from Clostridium to Clostridioides based on current (2019) accepted nomenclature for this genus [PMID:27370902].
Order vs. Observation
Both
Common Test Rank Get Info
12276

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Clostridioides difficile toxin Ab.neutralizační:Arbitrární koncentrace (titr):Časový bod:Sérum:Semikvantitativní:Neutralizační test
el-GRGreek (Greece)Τοξίνη του Clostridioides difficile Ab.Neut:Titr:Pt:Ορός:Ημιποσοτική:Ουδετερόφιλα
Synonyms: Ab.Neut Clostridioides difficile MICRO Pt Titr Αντίσωμα Ημιποσοτική Ορός Ουδετερόφιλα Τοξίνη του Clostridioides difficile
es-ARSpanish (Argentina)[anticuerpo anti - ] toxina de Clostridium difficile:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:neutralización
es-ESSpanish (Spain)Toxina de Clostridium difficile Anticuerpos antineutrófilos:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:Prueba de neutralización
Synonyms: Semicuantitativo
es-MXSpanish (Mexico)Toxina de Clostridioides difficile Ab:Título:Punto temporal:Suero:Cuantitativo:Prueba de neutralización
fr-FRFrench (France)Clostridioides difficile toxine Ac neutralisant:Titre:Ponctuel:Sérum:Semi-Quantitatif:Neutralisation
fr-CAFrench (Canada)Toxine du clostridioides difficile Ac.neut:Titre:Temps ponctuel:Sérum:SemiQn:Test de neutralisation
it-ITItalian (Italy)Clostridium difficile, tossina Ab.Neut:Titr:Pt:Siero:SemiQn:Neut
Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Siero Test di neutralizzazione Titolo Tossina di Clostridium difficile
ko-KRKorean (Korea, Republic Of)클로스트리디움 디피실리 독소 항체:역가:검사시점:혈청:정량:중화
nl-NLDutch (Netherlands)Clostridioides difficile toxine As.neutraliserend:titer:moment:serum:semikwantitatief:neutralisatietest
Synonyms: antistof; antilichaam Clostridium difficile Clostridium difficile toxine
pt-BRPortuguese (Brazil)Clostridium difficile toxina Ac:Título:Pt:Soro:Qn:Teste de neutralização
Synonyms: ; C dif Tox; C diff; C difficile; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Nt; NT; Neutralization test; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
zh-CNChinese (China)艰难梭菌毒素 抗体.中和:滴定度:时间点:血清:半定量型:中和试验
Synonyms: Ab;自身抗体 中和试验;中和抗体;中和 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 艰难梭状芽胞杆菌;艰难芽孢梭菌 艰难梭状芽胞杆菌毒素 Ab 艰难梭状芽胞杆菌毒素;艰难芽孢梭菌毒素 艰难梭状芽胞杆菌毒素抗体 艰难梭菌毒素 Ab 艰难芽孢梭菌毒素 Ab 艰难芽孢梭菌毒素抗体

Example Units

UnitSource
{titer}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=33947-3