Version 2.78

Status Information

Status
DEPRECATED
Comment
Avidity testing is only done for IgG to distinguish recent from past infections.
Map-To Long Common Name Mapping Guidance
52984-2 Cytomegalovirus IgG Ab avidity [Ratio] in Serum or Plasma by Immunoassay

Part Description

LP14255-1   Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html] Source: Regenstrief LOINC

Fully-Specified Name

Component
Cytomegalovirus Ab avidity
Property
ACnc
Time
Pt
System
Ser
Scale
Qn
Method

Additional Names

Short Name
Deprecated CMV Ab Avidity Ser-aCnc
Display Name
CMV Ab avidity Qn (S)
Consumer Name Alpha Get Info
Cytomegalovirus (CMV) Ab avidity, Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.10
Last Updated
Version 2.69
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
54037-7 HEDIS 2009 panel
57820-3 HEDIS 2010 panel
60442-1 HEDIS 2011 panel
67767-4 HEDIS 2012 panel
72199-3 HEDIS 2013 panel
74234-6 HEDIS 2014 Value Sets
75868-0 HEDIS 2015 Value Sets
79544-3 HEDIS 2016 Value Sets

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) avidez del [anticuerpo anti - ] citomegalovirus [Ac]:concentración arbitraria:punto en el tiempo:suero:cuantitativo:
es-ES Spanish (Spain) Citomegalovirus Avidez del anticuerpo:Concentración arbitraria:Punto temporal:Suero:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Citomegalovirus Ab avidez:Concentración arbitraria:Punto temporal:Suero:Cuantitativo:
et-EE Estonian (Estonia) Tsütomegaloviirus antikehade aviidsus:Acnc:Pt:S:Qn:
Synonyms: Juhuslik Kvantitatiivne Seerum
fr-CA French (Canada) Cytomégalovirus, Avidité des Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:
fr-BE French (Belgium) Cytomégalovirus Anticorps. Avidité des Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:
Synonyms: Anticorps CMV
it-IT Italian (Italy) Citomegalovirus avidità Ab:ACnc:Pt:Siero:Qn:
Synonyms: anticorpo Concentrazione Arbitraria Microbiologia Punto nel tempo (episodio) Siero test avidità degli anticorpi
ko-KR Korean (Korea, Republic Of) 거대세포바이러스 항체 결합활성:임의농도:검사시점:혈청:정량:
nl-NL Dutch (Netherlands) Cytomegalovirus As-aviditeit:eenheid/volume:moment:serum:kwantitatief:
Synonyms: antistof; antilichaam
pl-PL Polish (Poland) Wirus cytomegalii Ab awidność:stężenie w jednostkach umownych:punkt w czasie:surowica:ilościowy:
Synonyms: Awidność przeciwciał do cytomegalowirusa Cytomegalowirus Przecwciała do cytomegalowirusa
pt-BR Portuguese (Brazil) Citomegalovírus Ac avidez:ACnc:Pt:Soro:Qn:
Synonyms: ; CMV; Cytomgal; Cytomegalo virus; Arbitrary concentration; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
ru-RU Russian (Russian Federation) Цитомегаловирус Ат авидность:ПроизвКонц:ТчкВрм:Сыв:Колич:
Synonyms: Антитело Количественный Произвольная концентрация Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Cytomegalovirus Ab aviditi:SçKons:Zmlı:Ser:Kant:
Synonyms: Ak
zh-CN Chinese (China) 巨细胞病毒 抗体亲合力:任意型浓度:时间点:血清:定量型:
Synonyms: Ab 亲合力 Ab;自身抗体 CMV Ab CMV Ab 亲合力 CMV 抗体 CMV 抗体亲合力 CMV;涎腺病毒;细胞巨化病毒;细胞肥大病毒 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 巨细胞病毒 Ab 巨细胞病毒 Ab 亲合力 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间

Example Units

Unit Source
[arb'U]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=34403-6