Version 2.78

Part Description

LP207910-3   free DRUG/TOX
The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug PMID: 6636249. For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity. Source: Regenstrief LOINC

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
34540-5 Phenytoin free and total panel - Serum or Plasma
Indent3969-3 Phenytoin Free [Mass/volume] in Serum or Plasma R ug/mL
Indent3968-5 Phenytoin [Mass/volume] in Serum or Plasma R ug/mL

Fully-Specified Name

Component
Phenytoin free & total panel
Property
-
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Phenytoin Free+Total Pnl SerPl
Display Name
Phenytoin free and total panel
Consumer Name Alpha Get Info
Free and Total phenytoin panel, Blood

Basic Attributes

Class
PANEL.DRUG/TOX
Type
Laboratory
First Released
Version 2.10
Last Updated
Version 2.73
Change Reason
The Property for this term changed from "MCnc" to a dash "-" in order to promote the international reuse of panels. During the June 2015 meeting, the LOINC Committee agreed to allow users to substitute panel elements that a) agree on all other LOINC parts, and b) contain an analogous molar Property to a reference element with a mass Property or vice versa.
Order vs. Observation
Order
Common Test Rank Get Info
11574
Panel Type
Panel

Language Variants Get Info

Tag Language Translation
es-AR Spanish (Argentina) pruebas analíticas de fenitoína libre y total:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-ES Spanish (Spain) Panel de la fenitoína total y libre:Propiedades mixtas (sólo paneles):Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Panel total y libre de fenitoína:-:Punto temporal:Suero o Plasma:Cuantitativo:
fr-CA French (Canada) Phénytoïne libre & totale panel:-:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR French (France) Diphénylhydantoïne libre et totale panel:-:Ponctuel:Sérum/Plasma:Numérique:
it-IT Italian (Italy) Fenitoina libera & totale, panel:-:Pt:Siero/Plasma:Qn:
Synonyms: Fenitoina Libera Livelli farmacologici e tossicologia Panel fenitoina libera & totale Plasma Punto nel tempo (episodio) Set di prescrizione per livelli farmacologici e to Siero Siero o Plasma
nl-NL Dutch (Netherlands) fenytoïne vrij & totaal panel:-:moment:serum of plasma:kwantitatief:
pt-BR Portuguese (Brazil) Perfil de Fenitoína livre e total:MCnc:Pt:Sor/Plas:Qn:
Synonyms: ; Phenytoin Free+Total Pnl; Diphenylhydantoin; Dilantin; DPH; Dilj; DI-HYDAN; Epanutin; Fenantoin; Lehydan; Phenhydan; Sinergina; Zentropil; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Drugs; Tot; Totl; Pan; Panl; FR; Non-protein bound; PANEL.DRUG & TOXICOLOGY; PANEL.DRUG & TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU Russian (Russian Federation) Фенитоин свободный & общий панель:-:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Fenitoin serb ve total paneli:-:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 游离型与总苯妥英组套:-:时间点:血清/血浆:定量型:
Synonyms: C15H12N2O2;二苯乙内酰脲;苯妥营;二苯基乙内酰脲;二苯尿囊素 全体数量 全部 共计 医嘱套餐 医嘱套餐类 医嘱套餐组 医嘱组 医嘱组.药物/毒理学试验;组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）.药物/毒理学;医嘱组.药物与毒理学;医嘱组.药物与毒理学试验;医嘱组类.药物/毒理学;医嘱组类.药物/毒理学试验;医嘱组类.药物与毒理学;医嘱组类.药物与毒理学试验;实验室医嘱组类.药物/毒理学;实验室医嘱组类.药物/毒理学试验;实验室医嘱组类.药物与毒理学;实验室医嘱组类.药物与毒理学试验;药物与毒理学医嘱组;药物与毒理学医嘱组类 医嘱组合 医嘱组合类 医嘱组套 医嘱组套类 医嘱组类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 套餐 套餐医嘱 套餐医嘱组 套餐医嘱组类 实验室医嘱套餐 实验室医嘱套餐类 实验室医嘱组 实验室医嘱组合类 实验室医嘱组套 实验室医嘱组套类 实验室套餐医嘱组 实验室套餐医嘱组类 实验室检验项目医嘱组合类 实验室检验项目组合类 总 总和 总数 总量 总额 时刻;随机;随意;瞬间 检验医嘱组合类 检验项目医嘱组合类 检验项目组合类 毒品 毒品类 汇总 游离 游离型与总苯妥英（二苯乙内酰脲、二苯基乙内酰脲、二苯尿囊素、苯妥营）组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）;游离型与总计苯妥英医嘱组;苯妥英游离型与总计医嘱组 游离型苯妥英;游离苯妥英;苯妥英.游离;苯妥英（二苯乙内酰脲、二苯基乙内酰脲、二苯尿囊素、苯妥营）.游离型 组 组合 组合医嘱 组合类 组套 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 血清或血浆 非蛋白结合型 非蛋白质结合型

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=34540-5
Questionnaire definition
https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/34540-5