Version 2.76

Term Description

Antibodies to botulinum toxin type A may be responsible for therapeutic failure
Source: Regenstrief LOINC

Part Description

LP31258-4   Clostridium botulinum toxin A
Botulinum toxin is a neurotoxin produced by Clostridium botulinum, an anaerobic, gram-positive, spore-forming rod found on plants, in soil, water and the intestinal tracts of animals. Eight exotoxins (A, B, C1, C2, D, E, F and G) have been identified, all of which interfere with neural transmission by blocking the release of acetylcholine, the principal neurotransmitter at the neuromuscular junction. The toxins are used in the clinical management of various spastic medical conditions, strabismus and focal dystonias, hemifacial spasms, headaches, hyper-salivation and hyperhidrosis. Type A is the most potent toxin. In 2002 it was approved by the U.S. Food and Drug Administration for cosmetological uses. It is administered by injection into muscles or glands with the effects lasting approximately three months. Most patients require multiple treatments over many years and some develop tolerance to the injections due to the development of neutralizing antibodies to the toxin. Side effects are minor and transient. PMID: 20418969 Source: Regenstrief LOINC

Fully-Specified Name

Component
Clostridium botulinum toxin A Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method

Additional Names

Short Name
C bot Tox A Ab Ser Ql
Display Name
C. botulinum toxin A Ab Ql (S)
Consumer Name Alpha Get Info
Clostridium botulinum toxin A antibody, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.11
Last Updated
Version 2.70
Change Reason
Changed answer list from "Normative" to "Example" to fit the current LOINC model.; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG41628-5 Clostridium botulinum

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Clostridium botulinum Toxin A Ak:Nachweis oder Schwellenwert:Zeitpunkt:Serum:Ordinal:
es-AR Spanish (Argentina) CLOSTRIDIUM BOTULINUM TOXIN A:concentración arbitraria:punto en el tiempo:suero:ordinal:
es-ES Spanish (Spain) Toxina A del Clostridium botulinum Anticuerpos:PrThr:Punto temporal:Suero:Ord:
es-MX Spanish (Mexico) Toxina botulínica A Ab de Clostridium:Presencia o umbral:Punto temporal:Suero:Ordinal:
et-EE Estonian (Estonia) Clostridium botulinum toksiin A antikehad:PrThr:Pt:S:Ord:
Synonyms: Järgarvuline Juhuslik Seerum
fr-CA French (Canada) Toxine Clostridium botulinum A , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:
fr-FR French (France) Clostridium botulinum toxine A Ac:Présence/Seuil:Ponctuel:Sérum:Qualitatif:
fr-BE French (Belgium) Toxine Clostridium botulinum A Ac:PrThr:Temps ponctuel:Sérum:Ordinal:
Synonyms: Anticorps Clostridium botulinum A. Toxine Clostridium botulinum.Toxine
it-IT Italian (Italy) Clostridium botulinum, tossina A Ab:PrThr:Pt:Siero:Ord:
Synonyms: anticorpo Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero Tossina A di Clostridium botulinum Tossina di Clostridium botulinum
ko-KR Korean (Korea, Republic Of) 클로스트리디움 보튤리늄 독소 A 항체:임의농도:검사시점:혈청:순위척도:
nl-NL Dutch (Netherlands) Clostridium botulinum toxine A As:aanwezigheid:moment:serum:ordinaal:
Synonyms: antistof; antilichaam
pl-PL Polish (Poland) Clostridium botulinum toksyna A Ab:granica wykrywalności:punkt w czasie:surowica:półilościowy:
Synonyms: Clostridium botulinum Przeciwciała do toksyny A Clostridium botulinum Toksyna A Clostridium botulinum Toksyna Clostridium botulinum
pt-BR Portuguese (Brazil) Clostridium botulinum toxina A Ac:ACnc:Pt:Soro:Ord:
Synonyms: ; C bot Tox A; Botox; C botulinum; Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
ru-RU Russian (Russian Federation) Clostridium botulinum токсин A Ат:PrThr:ТчкВрм:Сыв:Пор:
Synonyms: Антитело Порядковый Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Clostridium botulinum toksin A Ab:MevcEşik:Zmlı:Ser:Srl:
Synonyms: Ak Mevcut
zh-CN Chinese (China) 肉毒梭菌毒素 A 抗体:存在情况或阈值:时间点:血清:序数型:
Synonyms: A 型 A 型抗体 Ab;自身抗体 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 时刻;随机;随意;瞬间 肉毒 A Ab 肉毒 A 型 Ab 肉毒 A 型抗体 肉毒 A 抗体 肉毒 A;肉毒 A 型;肉毒梭菌毒素 A 型;肉毒梭菌神经毒素 A;肉毒梭菌神经毒素 A 型;肉毒毒素 A;肉毒毒素 A 型 肉毒;肉毒梭菌神经毒素;肉毒毒素;肉毒芽孢梭菌毒素 肉毒梭状芽胞杆菌;肉毒芽孢梭菌 肉毒梭菌毒素 A Ab 肉毒梭菌毒素 A 型 Ab 肉毒梭菌毒素 A 型抗体 肉毒梭菌神经毒素 A Ab 肉毒梭菌神经毒素 A 型 Ab 肉毒梭菌神经毒素 A 型抗体 肉毒梭菌神经毒素 A 抗体 肉毒毒素 A Ab 肉毒毒素 A 型 Ab 肉毒毒素 A 型抗体 肉毒毒素 A 抗体

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