LOINC
Version 2.67

34664-3Clostridium botulinum toxin A Ab [Presence] in SerumActive

Term Description

Antibodies to botulinum toxin type A may be responsible for therapeutic failure
Source: Regenstrief LOINC

Part Description

LP31258-4   Clostridium botulinum toxin A
Botulinum toxin is a neurotoxin produced by Clostridium botulinum, an anaerobic, gram-positive, spore-forming rod found on plants, in soil, water and the intestinal tracts of animals. Eight exotoxins (A, B, C1, C2, D, E, F and G) have been identified, all of which interfere with neural transmission by blocking the release of acetylcholine, the principal neurotransmitter at the neuromuscular junction. The toxins are used in the clinical management of various spastic medical conditions, strabismus and focal dystonias, hemifacial spasms, headaches, hyper-salivation and hyperhidrosis. Type A is the most potent toxin. In 2002 it was approved by the U.S. Food and Drug Administration for cosmetological uses. It is administered by injection into muscles or glands with the effects lasting approximately three months. Most patients require multiple treatments over many years and some develop tolerance to the injections due to the development of neutralizing antibodies to the toxin. Side effects are minor and transient. [PMID: 20418969] Source: Regenstrief LOINC, A blood group

Fully-Specified Name

Component
Clostridium botulinum toxin A Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method

Additional Names

Short Name
C bot Tox A Ab Ser Ql
Display Name
C. botulinum toxin A Ab Ql (S)

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.11
Last Updated
Version 2.56
Change Reason
Changed answer list from "Normative" to "Example" to fit the current LOINC model.; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Groups

LG41628-5 Clostridium botulinum

Language Variants Get Info

zh-CNChinese (CHINA)
肉毒梭菌毒素 A 抗体:存在情况或阈值:时间点:血清:序数型:
nl-NLDutch (NETHERLANDS)
Clostridium botulinum toxine A As:aanwezigheid:moment:serum:ordinaal:
et-EEEstonian (ESTONIA)
Clostridium botulinum toksiin A antikehad:PrThr:Pt:S:Ord:
fr-BEFrench (BELGIUM)
Toxine Clostridium botulinum A Ac:PrThr:Temps ponctuel:Sérum:Ordinal:
fr-CAFrench (CANADA)
Toxine Clostridium botulinum A , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:
fr-FRFrench (FRANCE)
Clostridium botulinum toxine A Ac:Présence/Seuil:Ponctuel:Sérum:Qualitatif:
it-ITItalian (ITALY)
Clostridium botulinum, tossina A , Ab:PrThr:Pt:Siero:Ord:
ko-KRKorean (KOREA, REPUBLIC OF)
클로스트리디움 보튤리늄 독소 A 항체:임의농도:검사시점:혈청:순위척도:
pt-BRPortuguese (BRAZIL)
Clostridium botulinum toxina A Ac:ACnc:Pt:Soro:Ord:
ru-RURussian (RUSSIAN FEDERATION)
Clostridium botulinum токсин A Ат:PrThr:ТчкВрм:Сыв:Пор:
es-ARSpanish (ARGENTINA)
CLOSTRIDIUM BOTULINUM TOXIN A:concentración arbitraria:punto en el tiempo:suero:ordinal:
es-ESSpanish (SPAIN)
Toxina A del Clostridium botulinum Anticuerpos:PrThr:Punto temporal:Suero:Ord:
tr-TRTurkish (TURKEY)
Clostridium botulinum toksin A Ab:MevcEşik:Zmlı:Ser:Srl:

Example Units

Unit Source
Pos/Neg Original Submission

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=34664-3