Version 2.77

Part Description

LP16650-1   Histoplasma capsulatum
Histoplasmosis capsulatum is a dimorphic fungal pathogen with filamentous or yeast forms,depending on nutritional factors and temperature.The M antigen is a well-known glycoprotein used as a diagnostic antigen for acute histoplasmosis as it induces the first precipitins during disease. Monoclonal antibodies (mAbs) to the M antigen have been found to modify the pathogenesis of histoplasmosis.Given the shortcomings of current therapies, the administration of mAbs is being investigated. PMID: 22347215 The H band is less commonly seen than the M band and is indicative of chronic or severe acute infections with H capsulatum.

H. capsulatum is found in nature primarily as a saprophytic mold. The mold form is comprised of hyaline septate hyphae, which produce two different asexual reproduction structures, macroconidia and microconidia. The micronidia are believed to be responsible for disease propagation since their 2-6 µm size is well suited for disposition into the distal alveoli. Infection is typically acquired through inhalation of fungal propagules upon disturbances of contaminated soil or excreta. Environmental and genetic factors influence disease manifestations which can range from asymptomatic or mild influenza-like disease to a disseminated sepsis form. Manifestations depend on the magnitude of exposure, the host's immunological status and the virulence of the infective strain. Reactivation of latent infection can result in significant disease, particularly for immunosuppressed individuals. Despite the availability of potent antifungal drugs, nearly one in ten patients hospitalized with histoplasmosis dies. PMID: 17223625 Source: Regenstrief LOINC

Fully-Specified Name

Component
Histoplasma capsulatum Ag
Property
PrThr
Time
Pt
System
Urine
Scale
Ord
Method

Additional Names

Short Name
H capsul Ag Ur Ql
Display Name
H. capsulatum Ag Ql (U)
Consumer Name Alpha Get Info
Histoplasma capsulatum antigen, Urine

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.13
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
10035

Member of these Groups Get Info

LOINC Group Group Name
LG34253-1 Histoplasma capsulatum Ag|PrThr|Sys:ANYGU
LG36074-9 Histoplasma capsulatum Ag|PrThr|Urine

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Histoplasma capsulatum Ag:Nachweis oder Schwellenwert:Zeitpunkt:Urin:Ordinal:
es-AR Spanish (Argentina) [anticuerpo anti - ] Histoplasma capsulatum [Ac].IgM [Inmunoglobulina M]:concentración arbitraria:punto en el tiempo:orina:ordinal:
es-ES Spanish (Spain) Histoplasma capsulatum Antígeno:PrThr:Punto temporal:Orina:Ord:
es-MX Spanish (Mexico) Histoplasma capsulatum Ag:Presencia o umbral:Punto temporal:Orina:Ordinal:
et-EE Estonian (Estonia) Histoplasma capsulatum antigeen:PrThr:Pt:U:Ord:
Synonyms: Järgarvuline Juhuslik Uriin
fr-CA French (Canada) Histoplasma capsulatum , Ag:Présence-Seuil:Temps ponctuel:Urine:Ordinal:
fr-FR French (France) Histoplasma capsulatum Ag:Présence/Seuil:Ponctuel:Urine:Qualitatif:
fr-BE French (Belgium) Histoplasma capsulatum Ag:PrThr:Temps ponctuel:Urine:Ordinal:
Synonyms: Antigène
it-IT Italian (Italy) Histoplasma capsulatum , Ag:PrThr:Pt:Urine:Ord:
Synonyms: Microbiologia Presenza o Soglia Punto nel tempo (episodio)
ko-KR Korean (Korea, Republic Of) 히스토플라스마 캡슐라툼 항원:임의농도:검사시점:뇨:순위척도:
nl-NL Dutch (Netherlands) Histoplasma capsulatum Ag:aanwezigheid:moment:urine:ordinaal:
Synonyms: antigeen
pt-BR Portuguese (Brazil) Histoplasma capsulatum Ag:ACnc:Pt:Urina:Ord:
Synonyms: ; H capsul; H capsulatum; H farciminosum; Histoplasma farciminosum; Arbitrary concentration; Point in time; Random; Ur; UR; Urn; UA; Ql; Ordinal; QL; Qualitative; Qual; Screen; Antigen; Antigens; Histo; Histopl; Histoplasmos; Histoplasmosis; Microbiology
ru-RU Russian (Russian Federation) Histoplasma capsulatum Аг:PrThr:ТчкВрм:Моча:Пор:
Synonyms: Порядковый Точка во времени;Момент
tr-TR Turkish (Turkey) Histoplazma Kapsulatum Ag:MevcEşik:Zmlı:İdrar:Srl:
Synonyms: Antijen Mevcut
zh-CN Chinese (China) 荚膜组织胞浆菌 抗原:存在情况或阈值:时间点:尿液:序数型:
Synonyms: Ag 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 尿;小便;下泉 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 时刻;随机;随意;瞬间 皮疽组织胞浆菌 Ag 皮疽组织胞浆菌;美洲型组织胞浆菌;鼻疽性组织浆菌 皮疽组织胞浆菌抗原 组织胞浆菌属 组织胞浆菌病 美洲型组织胞浆菌 Ag 美洲型组织胞浆菌抗原 荚膜组织胞浆菌 Ag 鼻疽性组织浆菌 Ag 鼻疽性组织浆菌抗原

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=35734-3