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Part Description

LP14400-3   Hepatitis C virus
Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. NS4A is a cofactor of NS3 protease activity. NS3-NS4A protease is one target of anti-HCV drugs. NS4B is a membrane anchor for the replication complex, and NS5A plays a role in regulating viral replication. NS5B is an RNA-dependent RNA polymerase. [NCBI Books: NBK1630] Source: Regenstrief LOINC, NCBI Books: NBK1630

Reference Information

TypeSourceReference
Mapping GuidanceRegenstrief HelpViral load Mapper’s Guide for the Top 2000 plus LOINC Laboratory Observations

LOINC Names Get Info

Fully-Specified Name
Hepatitis C virus RNA:LaCnc:Pt:Ser/Plas:Qn:Probe.amp.tar
Long Common Name
Hepatitis C virus RNA [log units/volume] (viral load) in Serum or Plasma by NAA with probe detection
Short Name
HCV RNA SerPl NAA+probe-Log IU
Display Name
HCV RNA NAA+probe [Log units/Vol]
Consumer Name Alpha Get Info
Hepatitis C virus (HCV), Blood

Part Model Get Info

  • Component
    Hepatitis C virus RNA
    LP38335-3
    • Analyte
      Hepatitis C virus RNA
      LP38335-3
      • Component Numerator
        Hepatitis C virus RNA
        LP38335-3
        • Component Numerator Core
          Hepatitis C virus
          LP14400-3
        • Component Numerator Core Suffix
          RNA
          LP32423-3
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    LaCnc
    LP34325-8
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    Probe.amp.tar
    LP6464-4

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.13
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Both
Common Test Rank Get Info
1213

Member of these Panels

LOINCLong Common Name
75888-8HCV RNA screening tests - Meaningful Use set
50023-1Hepatitis C virus RNA panel (viral load) in Serum or Plasma by NAA with probe detection

Member of these Groups Get Info

LOINC GroupGroup Name
LG32754-0Hepatitis C virus

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Virus hepatitidy C RNA:Koncentrace v log měřítku:Časový bod:Sérum/plazma:Kvantitativní:Amplifikace nukleových kyselin s detekcí sondou
de-DEGerman (Germany)Hepatitis-C-Virus RNA:Logarithmische Einheitenkonzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:Zielfragmentamplifikation mit Sondendetektion
Synonyms: Hepacivirus C; HCV
el-GRGreek (Greece)Ιός Ηπατίτιδας C RNA:LaCnc:Pt:Ορός/Πλάσμα:Qn:Ανιχνευτής.ενίσχυση.στόχου
Synonyms: C LaCnc MICRO Pt Qn RNA Ανιχνευτής Ανιχνευτής.ενίσχυση Ανιχνευτής.ενίσχυση.στόχου Ιός Ιός ηπατίτιδας C Ορός Ορός/Πλάσμα Πλάσμα
es-ARSpanish (Argentina)[anticuerpo anti - ] virus de la coriomeningitis linfocítica [Ac].IgM [Inmunoglobulina M]:LACNC:punto en el tiempo:suero/plasma:cuantitativo:sonda.amplificación.blanco
es-ESSpanish (Spain)Virus Hepatitis C RNA:Concentración logarítmica:Punto temporal:Suero o Plasma:Qn:Sonda con amplificación dirigida
Synonyms: Cuantitativo
es-MXSpanish (Mexico)ARN del virus de la hepatitis C:Concentración de unidades logarítmicas:Punto temporal:Suero o Plasma:Cuantitativo:Amplificación de ácidos nucleicos con detección de sonda
fr-CAFrench (Canada)Virus de l'hépatite C ARN:Concentration arbitraire exprimée en log:Temps ponctuel:Sérum/Plasma:Quantitatif:Sonde avec amplification de la cible
fr-FRFrench (France)Hépatite C virus ARN:Log arbitraire/Volume:Ponctuel:Sérum/Plasma:Numérique:PCR amplification de cible
fr-BEFrench (Belgium)Virus de l'hépatite C ARN:Concentration arbitraire exprimée en log:Temps ponctuel:Sérum/Plasma:Quantitatif:Sonde avec amplification de la cible
Synonyms: Concentration Log HCV
it-ITItalian (Italy)Epatite C, virus RNA:LaCnc:Pt:Siero/Plasma:Qn:Sonda.amp.tar
Synonyms: Concentrazione logaritmica Microbiologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA Virus dell''epatite C
ko-KRKorean (Korea, Republic Of)C형 간염 바이러스 리보핵산:로그임의농도:검사시점:혈청/혈장:정량:DNA 탐색자.증폭.표적
nl-NLDutch (Netherlands)Hepatitis C-virus RNA:logaritmische eenheid/volume:moment:serum of plasma:kwantitatief:probe-detectie
Synonyms: probe.amp.tar
pl-PLPolish (Poland)Wirus zapalenia wątroby typu C RNA:stężenie logarytmowo-jednostkowe:punkt w czasie:surowica lub osocze:ilościowy:sonda.amplifikacja.cel
Synonyms: amplifikacja kwasu nukleinowego z detekcją za pomocą sondy amplifikacja z detekcją za pomocą sondy RNA wirusa zapalenia wątroby typu C
pt-BRPortuguese (Brazil)Hepatite C vírus RNA:LaCnc:Pt:Sor/Plas:Qn:Sonda com limite de detecção da amplificação de alvo
Synonyms: Ribonucleic acid; HCV; Hep C; Log IU; Log ACNC; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; PCR; Polymerase chain reaction; Transcription mediated amplification; NASBA; Nucleic acid sequence based analysis; SDA; Strand Displacement Amplification; LAT; Ligation-activated transcription; 3SR SR; 3 Self-Sustaining Sequence Replication; LCR; Ligase chain reaction; QBR; Q-Beta Replicase or probe amplification category method; Probe with target amplification; NAAT; TMA; Amp Prb; Probe with ampification; DNA probe; Amplified; Hepatit; Hepatis; Microbiology; Viral load
ru-RURussian (Russian Federation)Гепатита С вирус РНК:LaCnc:ТчкВрм:Сыв/Плаз:Колич:Проба.усил.миш
Synonyms: ДНК проба;ДНК зонд Количественный Концентрация в логарифмических единицах Плазма Проба с мишени усилением Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TRTurkish (Turkey)Hepatit C virüsü RNA:LogKons:Zmlı:Ser/Plaz:Kant:Prob.amf.hdf
uk-UAUkrainian (Ukraine)Вірусу Гепатиту С РНК:Log Довільна Концентрація:МоментЧасу:Сироватка/Плазма:Кількісно:Зонд-детекція. цільова аміпліфікація НК
Synonyms: 3 Self-Sustaining Sequence Replication; 3SR SR; Amplif; Amplification; Amplified; DNA NUCLEIC ACID PROBE; DNA probe; HCV; Hep; Hep C; Hepatis; Hepatit; Hepatology; ID; Infectious Disease; InfectiousDisease; LAT; LCR; Ligase chain reaction; Ligation-activated transcription; Liver; Log ACNC; Log IU; Microbiology; NAA+probe; NAAT; NASBA; Nucleic acid sequence based analysis; PCR; Pl; Plasma; Plsm; Point in time; Polymerase chain reaction; Probe amp; Probe with ampification; Probe with target amplification; QBR; QNT; Quan; Quant; Quantitative; Random; Ribonucleic acid; SDA; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR; Strand Displacement Amplification; TMA; Transcription mediated amplification; UniversalLabOrders; Viral load
zh-CNChinese (China)丙型肝炎病毒 RNA:对数型任意浓度:时间点:血清/血浆:定量型:探针法.基因扩增.靶向
Synonyms: C 型;丙;丙型 HCV RNA HCV;Hep C;丙型肝炎;丙肝;丙肝病毒;肝炎病毒 C 型 Hep C RNA 丙肝病毒 RNA 传染性肝炎 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 借助扩增的探针方法;借助扩增的探针法;探针法.扩增 借助靶向扩增的探针方法;借助靶向扩增的探针法;探针法.扩增.靶向 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 对数任意浓度 探针法.基因扩增.靶向 对数任意浓度 探针法.扩增.靶向 对数任意浓度;任意浓度之对数 对数型任意浓度 探针法.扩增.靶向 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 扩增型 扩增性 时刻;随机;随意;瞬间 核糖核酸;Ribonucleic acid 病毒负荷 病毒负荷量 病毒负载 病毒载量 病毒载量（Viral load） 经过扩增的 肝 肝炎病毒 C 型 RNA 脱氧核糖核酸探针 血清或血浆

Example Units

UnitSource
Log IU/mLREGENSTRIEF
{Log_IU}/mLExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=38180-6