39020-3
Abnormal Prion Protein [Presence] in Tissue by Immune stain
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Part Description
LP35078-2 Prion protein.abnormal
Transmissible spongiform encephalopathies (TSEs), also known as prion diseases, are a group of progressive conditions (encephalopathies) that affect the brain and nervous system of many animals, including humans. According to the most widespread hypothesis they are transmitted by abnormal prions, though some other data suggest an involvement of a Spiroplasma infection. Mental and physical abilities deteriorate and a myriad of tiny holes appear in the cortex causing it to appear like a sponge (hence spongiform) when brain tissue obtained at autopsy is examined under a microscope. The disorders cause impairment of brain function, including memory changes, personality changes and problems with movement that worsen over time. Most TSEs are sporadic and occur in animals. Prion diseases of animals in include classical bovine spongiform encephalopathy (BSE) (C-type), atypical (H or L-type) BSE, Scrapie, atypical scrapie, Nor98, and chronic wasting disease (CWE). H-type and L-type BSE were named based on abnormal prion bands migrating to a higher (H) or lower (L) position on western blot analysis compared to the classical BSE (C-type) prion protein. Prion diseases of humans include classic Creutzfeldt-Jakob disease, new variant Creutzfeldt-Jakob disease (nvCJD, a human disorder related to Bovine spongiform encephalopathy), Gerstmann-Sträussler-Scheinker syndrome, fatal familial insomnia and kuru. These conditions form a spectrum of diseases with overlapping signs and symptoms.
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Source: Wikipedia,
Transmissible spongiform encephalopathy
LOINC Names Get Info
- Fully-Specified Name
- Prion protein.abnormal:
PrThr: Pt: Tiss: Ord: Immune stain - Long Common Name
- Abnormal Prion Protein [Presence] in Tissue by Immune stain
- Short Name
- Abn Prion Prot Tiss Ql ImStn
- Display Name
- Abnormal Prion Protein Immune stain Ql (Tiss)
- Consumer Name Alpha Get Info
- Abnormal prion protein, Tissue
Part Model Get Info
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.15
- Last Updated
- Version 2.56 (MAJ)
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Prionový protein abnormální: |
| de-DE | German (Germany) | Prionenprotein.abnorm: |
| el-GR | Greek (Greece) | Πρωτεΐνη πριόν.μη φυσιολογική: Synonyms: MICRO Ord PrThr Pt Ανοσολογική χρώση Ιστός Πρωτεΐνη Πρωτεΐνη πριόν.μη φυσιολογική |
| es-ES | Spanish (Spain) | Proteína priónica anormal: |
| es-MX | Spanish (Mexico) | Proteína priónica anormal: |
| fr-CA | French (Canada) | Protéines prion.anormales: |
| fr-FR | French (France) | Protéine prion anormale: |
| fr-BE | French (Belgium) | Protéines prion.anormales: Synonyms: Coloration. Méthode mmunologique |
| it-IT | Italian (Italy) | Proteina prionica.anormale: Synonyms: Microbiologia Presenza o Soglia Proteina Prionica Anormale Punto nel tempo (episodio) Tessuto & |
| ko-KR | Korean (Korea, Republic Of) | 프리온 단백.이상: |
| nl-NL | Dutch (Netherlands) | prioneiwit.abnormaal: |
| pl-PL | Polish (Poland) | Białko prionowe.nieprawidłowe: Synonyms: Nieprawidłowe białko prionowe |
| pt-BR | Portuguese (Brazil) | Proteína prion.anormal: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Прионный протеин.аномальный: Synonyms: Белок Порядковый Прионный белок.аномальный Ткань и мазки Точка во времени; |
| tr-TR | Turkish (Turkey) | Prion protein.anormal: Synonyms: Mevcut |
| zh-CN | Chinese (China) | 朊病毒蛋白.异常: Synonyms: BSE; |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://