Version 2.76

Part Description

LP35078-2   Prion protein.abnormal
Transmissible spongiform encephalopathies (TSEs), also known as prion diseases, are a group of progressive conditions (encephalopathies) that affect the brain and nervous system of many animals, including humans. According to the most widespread hypothesis they are transmitted by abnormal prions, though some other data suggest an involvement of a Spiroplasma infection. Mental and physical abilities deteriorate and a myriad of tiny holes appear in the cortex causing it to appear like a sponge (hence spongiform) when brain tissue obtained at autopsy is examined under a microscope. The disorders cause impairment of brain function, including memory changes, personality changes and problems with movement that worsen over time. Most TSEs are sporadic and occur in animals. Prion diseases of animals in include classical bovine spongiform encephalopathy (BSE) (C-type), atypical (H or L-type) BSE, Scrapie, atypical scrapie, Nor98, and chronic wasting disease (CWE). H-type and L-type BSE were named based on abnormal prion bands migrating to a higher (H) or lower (L) position on western blot analysis compared to the classical BSE (C-type) prion protein. Prion diseases of humans include classic Creutzfeldt-Jakob disease, new variant Creutzfeldt-Jakob disease (nvCJD, a human disorder related to Bovine spongiform encephalopathy), Gerstmann-Sträussler-Scheinker syndrome, fatal familial insomnia and kuru. These conditions form a spectrum of diseases with overlapping signs and symptoms. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Transmissible spongiform encephalopathy

Fully-Specified Name

Component
Prion protein.abnormal
Property
PrThr
Time
Pt
System
Tiss
Scale
Ord
Method
IA

Additional Names

Short Name
Abn Prion Prot Tiss Ql IA
Display Name
Abnormal Prion Protein IA Ql (Tiss)
Consumer Name Alpha Get Info
Abnormal prion protein, Tissue

Example Answer List: LL2038-9

Source: Quest Diagnostics Inc.
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6
IndeterminateCopyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) LA11884-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.15
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Prionenprotein.abnormal:Nachweis oder Schwellenwert:Zeitpunkt:Gewebe:Ordinal:Immunoassay
es-ES Spanish (Spain) Proteína priónica anormal:PrThr:Punto temporal:Tejido:Ord:IA
es-MX Spanish (Mexico) Proteína priónica anormal:Presencia o umbral:Punto temporal:Tejido y frotis:Ordinal:Inmunoensayo
fr-CA French (Canada) Protéines prion.anormales:Présence-Seuil:Temps ponctuel:Tissu:Ordinal:IA
fr-FR French (France) Protéine prion anormale:Présence/Seuil:Ponctuel:Tissu:Qualitatif:Immunoanalyse
fr-BE French (Belgium) Protéines prion.anormales:PrThr:Temps ponctuel:Tissu:Ordinal:IA
it-IT Italian (Italy) Proteina prionica.anormale:PrThr:Pt:Tessuto:Ord:IA
Synonyms: Immunoassay Microbiologia Presenza o Soglia Proteina Prionica Anormale Punto nel tempo (episodio) Tessuto & Strisci
ko-KR Korean (Korea, Republic Of) 프리온 단백.이상:임의농도:검사시점:조직:순위척도:효소면역측정법
nl-NL Dutch (Netherlands) prioneiwit.abnormaal:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:immunoassay
Synonyms: IA
pt-BR Portuguese (Brazil) Proteína prion.anormal:ACnc:Pt:Tecido:Ord:Imunoensaio
Synonyms: ; Prot; PR; Acn Prion Prot; Scrapie; Bovine spongiform encephalopathy; BSE; Arbitrary concentration; Point in time; Random; Tissue; Ql; Ordinal; QL; Qualitative; Qual; Screen; Enzyme immunoassay; ELISA; MEIA; SUDS; ELFA; IAA; Acn; Acnorm; Microbiology
ru-RU Russian (Russian Federation) Прионный протеин.аномальный:PrThr:ТчкВрм:Тк:Пор:IA
Synonyms: Белок Порядковый Прионный белок.аномальный Ткань и мазки Точка во времени;Момент
tr-TR Turkish (Turkey) Prion protein.anormal:MevcEşik:Zmlı:Doku:Srl:İA
Synonyms: İmmünölçüm, immünoassay Mevcut
zh-CN Chinese (China) 朊病毒蛋白.异常:存在情况或阈值:时间点:组织与涂片:序数型:免疫测定法
Synonyms: BSE;Scrapie;亲染子蛋白.异常;异常亲染子蛋白;异常感染性蛋白质;异常朊病毒蛋白;异常蛋白感染素;感染性蛋白质.异常;牛海绵状脑病;牛海绵状脑病(Bovine spongiform encephalopathy,BSE);疯牛病;羊痒病;羊瘙痒病;羊瘙痒病(Scrapie);蛋白感染素.异常 PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质 不平常的 不正常的 亲染子蛋白 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 反常的 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 异常的 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 感染性蛋白质 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 蛋白感染素 非一般的 非惯例的

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=39021-1