39311-6
Influenza virus A N1 neutralizing antibody [Presence] in Serum by Neutralization test
Active
Part Descriptions
LP207365-0 Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method.
Source: Regenstrief LOINC
LP6416-4 Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Influenza virus A N1 Ab.Neut
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- Neut
Additional Names
- Short Name
- FLUAV N1 NAb Ser Ql Nt
- Display Name
- FLUAV N1 neut ab Neut test Ql (S)
- Consumer Name Alpha Get Info
- Influenza A N1 neutralizing antibody, Blood
Example Answer List: LL360-9
Source: Regenstrief InstituteAnswer | Code | Score | Answer ID |
---|---|---|---|
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.15
- Last Updated
- Version 2.72
- Change Reason
- Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.; Previous Releases: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Updated Answer list type from NORMATIVE to EXAMPLE because the Answers in the list (Positive, Negative) are only examples of possible answers and not an exclusive list
- Order vs. Observation
- Both
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG32757-3 | Influenza virus |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Neuraminidasa N1 del virus Influenza A Anticuerpos antineutrófilos: |
es-MX | Spanish (Mexico) | Virus de la influenza A N1 Ab: |
fr-FR | French (France) | Influenza virus A N1 Ac neutralisant: |
fr-CA | French (Canada) | N1 influenza type A Ac.neut: |
it-IT | Italian (Italy) | Influenza virus A N1 Ab.Neut: Synonyms: anticorpo Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero Test di neutralizzazione Virus dell''influenza Virus dell''influenza A Virus dell''infuenza A N1 |
ko-KR | Korean (Korea, Republic Of) | A형 인플루엔자 바이러스 뉴라민분해효소 N1 항체: |
nl-NL | Dutch (Netherlands) | Influenzavirus A N1 As.neutraliserend: Synonyms: antistof; |
pl-PL | Polish (Poland) | Influenza wirus A N1 Ab.Neutralizujące: Synonyms: Białko N1 wirusa grypy typu A Przeciwciała do białka N1 wirusa grypy typu A Przeciwciała neutralizujące do białka N1 wirusa grypy typu A Wirus grypy Wirus grypy typ A |
pt-BR | Portuguese (Brazil) | Influenza vírus A N1 Ac: Synonyms: ; |
zh-CN | Chinese (China) | 流感病毒 A 型神经氨酸酶 N1 型 抗体.中和: Synonyms: A 型 A 型流感; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=39311-6
Third Party Copyright
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LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright