Log In

Part Descriptions

LP207365-0   Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP6416-4   Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Influenza virus A N4 Ab.Neut:PrThr:Pt:Ser:Ord:Neut
Long Common Name
Influenza virus A N4 neutralizing antibody [Presence] in Serum by Neutralization test
Short Name
FLUAV N4 NAb Ser Ql Nt
Display Name
FLUAV N4 neut ab Neut test Ql (S)
Consumer Name Alpha Get Info
Influenza A N4 neutralizing antibody, Blood

Part Model Get Info

  • Component
    Influenza virus A N4 Ab.Neut
    LP430407-9
    • Analyte
      Influenza virus A N4 Ab.Neut
      LP430407-9
      • Component Numerator
        Influenza virus A N4 Ab.Neut
        LP430407-9
        • Component Numerator Core
          Influenza virus A N4
          LP35186-3
        • Component Numerator Core Suffix
          Ab.Neut
          LP207365-0
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    Neut
    LP6416-4

Example Answer List: LL360-9

Source: Regenstrief Institute
AnswerCodeScoreAnswer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)LA6577-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.15
Last Updated
Version 2.72 (NAM)
Change Reason
Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.; Previous Releases: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Updated Answer list type from NORMATIVE to EXAMPLE because the Answers in the list (Positive, Negative) are only examples of possible answers and not an exclusive list
Order vs. Observation
Both

Member of these Groups Get Info

LOINC GroupGroup Name
LG32757-3Influenza virus

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Virus chřipky A N4 Ab.neutralizační:Přítomnost nebo práh:Časový bod:Sérum:Ordinální:Neutralizační test
el-GRGreek (Greece)Ιός γρίπης A N4 Ab.Neut:PrThr:Pt:Ορός:Ord:Ουδετερόφιλα
Synonyms: A Ab.Neut MICRO Ord PrThr Pt Αντίσωμα Ιός Ιός γρίπης Ιός γρίπης A Ιός γρίπης A N4 Ορός Ουδετερόφιλα
es-ESSpanish (Spain)Neuraminidasa N4 del virus Influenza A Anticuerpos antineutrófilos:PrThr:Punto temporal:Suero:Ord:Prueba de neutralización
es-MXSpanish (Mexico)Virus de la influenza A N4 Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Prueba de neutralización
fr-FRFrench (France)Influenza virus A N4 Ac neutralisant:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Neutralisation
fr-CAFrench (Canada)N4 influenza type A Ac.neut:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Test de neutralisation
it-ITItalian (Italy)Influenza virus A N4 Ab.Neut:PrThr:Pt:Siero:Ord:Neut
Synonyms: anticorpo Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero Test di neutralizzazione Virus dell''influenza Virus dell''influenza A Virus dell''infuenza A N4
ko-KRKorean (Korea, Republic Of)A형 인플루엔자 바이러스 뉴라민분해효소 N4 항체:임의농도:검사시점:혈청:순위척도:중화
nl-NLDutch (Netherlands)Influenzavirus A N4 As.neutraliserend:aanwezigheid:moment:serum:ordinaal:neutralisatietest
Synonyms: antistof; antilichaam
pl-PLPolish (Poland)Influenza wirus A N4 Ab.Neutralizujące:granica wykrywalności:punkt w czasie:surowica:uporządkowany:test neutralizacji
Synonyms: Białko N4 wirusa grypy typu A Przeciwciała do białka N4 wirusa grypy typu A Przeciwciała neutralizujące do białka N4 wirusa grypy typu A Wirus grypy typ A
pt-BRPortuguese (Brazil)Influenza vírus A N4 Ac:ACnc:Pt:Soro:Ord:Teste de neutralização
Synonyms: ; FLUAV N4; Avian influenza; Fowl plague; Influenza A virus; FLUA; Bird flu; FLUV; Influ; Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; Nt; NT; Neutralization test; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
zh-CNChinese (China)流感病毒 A 型神经氨酸酶 N4 型 抗体.中和:存在情况或阈值:时间点:血清:序数型:中和试验
Synonyms: A 型 A 型流感;A 型流感病毒;FLUA;FLUAV;家禽鼠疫;流感 A;流感 A 型;流感甲型;流感病毒甲型;甲型流感;甲型流感病毒;瘟疫;禽流感;禽流行性感冒;禽疫;鸡瘟 A 型流感病毒神经氨酸酶 N4 型 Ab A 型流感病毒神经氨酸酶 N4 型;FLUA NA N4;FLUA NA N4 型;FLUA 神经氨酸酶 N4 型;FLUAV NA N4;FLUAV NA N4 型;FLUAV 神经氨酸酶 N4 型;流感病毒甲型神经氨酸酶 N4 型;甲型流感病毒神经氨酸酶 N4 型 A 型流感病毒神经氨酸酶 N4 型抗体 Ab;自身抗体 FLUA NA N4 Ab FLUA NA N4 型 Ab FLUA NA N4 型抗体 FLUA NA N4 抗体 FLUA 神经氨酸酶 N4 型 Ab FLUA 神经氨酸酶 N4 型抗体 FLUAV NA N4 Ab FLUAV NA N4 型 Ab FLUAV NA N4 型抗体 FLUAV NA N4 抗体 FLUAV 神经氨酸酶 N4 型 Ab FLUAV 神经氨酸酶 N4 型抗体 FLUV;Influ;列性感冒病毒;流行性感冒病毒 中和试验;中和抗体;中和 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 流感病毒 A 型神经氨酸酶 N4 型 Ab 流感病毒甲型神经氨酸酶 N4 型 Ab 流感病毒甲型神经氨酸酶 N4 型抗体 甲型流感病毒神经氨酸酶 N4 型 Ab 甲型流感病毒神经氨酸酶 N4 型抗体

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=39314-0