Version 2.78

Part Descriptions

LP207365-0   Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP6416-4   Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

Fully-Specified Name

Component
Influenza virus A N8 Ab.Neut
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
Neut

Additional Names

Short Name
FLUAV N8 NAb Ser Ql Nt
Display Name
FLUAV N8 neut ab Neut test Ql (S)
Consumer Name Alpha Get Info
Influenza A N8 neutralizing antibody, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.15
Last Updated
Version 2.72
Change Reason
Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.; Previous Releases: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Updated Answer list type from NORMATIVE to EXAMPLE because the Answers in the list (Positive, Negative) are only examples of possible answers and not an exclusive list
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG32757-3 Influenza virus

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Neuraminidasa N8 del virus Influenza A Anticuerpos antineutrófilos:PrThr:Punto temporal:Suero:Ord:Prueba de neutralización
es-MX Spanish (Mexico) Virus de la influenza A N8 Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Prueba de neutralización
fr-FR French (France) Influenza virus A N8 Ac neutralisant:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Neutralisation
fr-CA French (Canada) N8 influenza type A Ac.neut:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Test de neutralisation
it-IT Italian (Italy) Influenza virus A N8 Ab.Neut:PrThr:Pt:Siero:Ord:Neut
Synonyms: anticorpo Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero Test di neutralizzazione Virus dell''influenza Virus dell''influenza A Virus dell''influenza A N8
ko-KR Korean (Korea, Republic Of) A형 인플루엔자 바이러스 뉴라민분해효소 N8 항체:임의농도:검사시점:혈청:순위척도:중화
nl-NL Dutch (Netherlands) Influenzavirus A N8 As.neutraliserend:aanwezigheid:moment:serum:ordinaal:neutralisatietest
Synonyms: antistof; antilichaam
pl-PL Polish (Poland) Influenza wirus A N8 Ab.Neutralizujące:granica wykrywalności:punkt w czasie:surowica:półilościowy:test neutralizacji
Synonyms: Białko N8 wirusa grypy typu A Przeciwciała do białka N8 wirusa grypy typu A Przeciwciała neutralizujące do białka N8 wirusa grypy typu A Wirus grypy Wirus grypy typ A
pt-BR Portuguese (Brazil) Influenza vírus A N8 Ac:ACnc:Pt:Soro:Ord:Teste de neutralização
Synonyms: ; FLUAV N8; Avian influenza; Fowl plague; Influenza A virus; FLUA; Bird flu; FLUV; Influ; Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; Nt; NT; Neutralization test; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
zh-CN Chinese (China) 流感病毒 A 型神经氨酸酶 N8 型 抗体.中和:存在情况或阈值:时间点:血清:序数型:中和试验
Synonyms: A 型 A 型流感;A 型流感病毒;FLUA;FLUAV;家禽鼠疫;流感 A;流感 A 型;流感甲型;流感病毒甲型;甲型流感;甲型流感病毒;瘟疫;禽流感;禽流行性感冒;禽疫;鸡瘟 A 型流感病毒神经氨酸酶 N8 型 Ab A 型流感病毒神经氨酸酶 N8 型;FLUA NA N8;FLUA NA N8 型;FLUA 神经氨酸酶 N8 型;FLUAV NA N8;FLUAV NA N8 型;FLUAV 神经氨酸酶 N8 型;流感病毒甲型神经氨酸酶 N8 型;甲型流感病毒神经氨酸酶 N8 型 A 型流感病毒神经氨酸酶 N8 型抗体 Ab;自身抗体 FLUA NA N8 Ab FLUA NA N8 型 Ab FLUA NA N8 型抗体 FLUA NA N8 抗体 FLUA 神经氨酸酶 N8 型 Ab FLUA 神经氨酸酶 N8 型抗体 FLUAV NA N8 Ab FLUAV NA N8 型 Ab FLUAV NA N8 型抗体 FLUAV NA N8 抗体 FLUAV 神经氨酸酶 N8 型 Ab FLUAV 神经氨酸酶 N8 型抗体 FLUV;Influ;列性感冒病毒;流行性感冒病毒 中和试验;中和抗体;中和 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 流感病毒 A 型神经氨酸酶 N8 型 Ab 流感病毒甲型神经氨酸酶 N8 型 Ab 流感病毒甲型神经氨酸酶 N8 型抗体 甲型流感病毒神经氨酸酶 N8 型 Ab 甲型流感病毒神经氨酸酶 N8 型抗体

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=39318-1