3969-3
Phenytoin Free [Mass/volume] in Serum or Plasma
Active
Part Descriptions
LP14731-1 Phenytoin.free
Phenytoin-free levels detect the level of non-protein-bound phenytoin in the blood. It is used to measure therapeutic and toxic levels of the drug.
Source: Regenstrief Institute
LP207910-3 free DRUG/TOX
The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug PMID: 6636249. For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Phenytoin.free
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
Additional Names
- Short Name
- Phenytoin Free SerPl-mCnc
- Display Name
- Phenytoin Free [Mass/Vol]
- Consumer Name Alpha Get Info
- Free phenytoin, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.73
- Change Reason
- Changed Order_Obs from 'Observation Only' to fit the current order use cases.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 1466
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 54037-7 | HEDIS 2009 panel |
| 57820-3 | HEDIS 2010 panel |
| 60442-1 | HEDIS 2011 panel |
| 67767-4 | HEDIS 2012 panel |
| 72199-3 | HEDIS 2013 panel |
| 74234-6 | HEDIS 2014 Value Sets |
| 34540-5 | Phenytoin free and total panel - Serum or Plasma |
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG47569-5 | Phenytoin.free| |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Phenytoin.frei: |
| es-MX | Spanish (Mexico) | Phenytoin.libre: |
| es-AR | Spanish (Argentina) | fenitoína.libre: |
| es-ES | Spanish (Spain) | Fenitoína libre: Synonyms: Cuantitativo |
| et-EE | Estonian (Estonia) | Fenütoiin.vaba: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma |
| fr-CA | French (Canada) | Phénytoïne.libre: |
| fr-FR | French (France) | Diphénylhydantoïne libre: |
| fr-BE | French (Belgium) | Phénytoïne.libre: |
| it-IT | Italian (Italy) | Fenitoina.libera: Synonyms: Concentrazione di Massa Fenitoina Libera Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
| ko-KR | Korean (Korea, Republic Of) | 유리페니토인: |
| nl-NL | Dutch (Netherlands) | fenytoïne.vrij: |
| pt-BR | Portuguese (Brazil) | Fenitoína.livre: Synonyms: Diphenylhydantoin; |
| ru-RU | Russian (Russian Federation) | Фенитоин.свободный: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени; |
| tr-TR | Turkish (Turkey) | Fenitoin.serb: |
| zh-CN | Chinese (China) | 苯妥英.游离型: Synonyms: C15H12N2O2; |
Example Units
| Unit | Source |
|---|---|
| mcg/mL | REGENSTRIEF |
| ug/mL | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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LOINC Copyright
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