3969-3

Phenytoin Free [Mass/volume] in Serum or Plasma

Active

Part Descriptions

LP14731-1 Phenytoin.free
Phenytoin-free levels detect the level of non-protein-bound phenytoin in the blood. It is used to measure therapeutic and toxic levels of the drug. Source: Regenstrief Institute

LP207910-3 free DRUG/TOX
The measurement of free (unbound) drug concentrations in plasma is important for certain drugs and has two advantages over measurement of total concentration: (1) the free concentration is independent of changes in plasma binding (e.g., due to changes in albumin), and (2) the free concentration is more directly related to both the efficacy and toxicity of the drug PMID: 6636249. For most drugs and the majority of patients, measuring the free and total concentrations is not necessary. However, for certain drugs, including some anticonvulsants and antibiotics, and specific patient populations, such as critically ill or immunosuppressed patients, the free concentration is a better indicator of therapeutic effect and potential toxicity. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Phenytoin.free:MCnc:Pt:Ser/Plas:Qn:
Long Common Name: Phenytoin Free [Mass/volume] in Serum or Plasma
Short Name: Phenytoin Free SerPl-mCnc
Display Name: Phenytoin Free [Mass/Vol]
Consumer Name Alpha Get Info: Free phenytoin, Blood

Part Model Get Info

Component
Phenytoin.free
LP14731-1
- Analyte
  Phenytoin.free
  LP14731-1
  - Component Numerator
    Phenytoin.free
    LP14731-1
    - Component Numerator Core
      Phenytoin.free
      LP14731-1
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 1.0
Last Updated: Version 2.73 (MIN)
Change Reason: Changed Order_Obs from 'Observation Only' to fit the current order use cases.
Order vs. Observation: Both
Common Test Rank Get Info: 1466

Member of these Panels

LOINC	Long Common Name
54037-7	HEDIS 2009 panel
57820-3	HEDIS 2010 panel
60442-1	HEDIS 2011 panel
67767-4	HEDIS 2012 panel
72199-3	HEDIS 2013 panel
74234-6	HEDIS 2014 Value Sets
34540-5	Phenytoin free and total panel - Serum or Plasma

Member of these Groups Get Info

LOINC Group	Group Name
LG47569-5	Phenytoin.free\|Pt\|Ser/Plas

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Fenytoin volný:Hmotnostní koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
de-DE	German (Germany)	Phenytoin.frei:Massenkonzentration:Zeitpunkt:Serum oder Plasma:Quantitativ:
el-GR	Greek (Greece)	Φαινυτοΐνη.ελεύθερη:MCnc:Pt:Ορός/Πλάσμα:Qn: Synonyms: DRUG/TOX MCnc Pt Qn Ορός Ορός/Πλάσμα Πλάσμα Φαινυτοΐνη Φαινυτοΐνη.ελεύθερη
es-MX	Spanish (Mexico)	Phenytoin.libre:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
es-AR	Spanish (Argentina)	fenitoína.libre:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-ES	Spanish (Spain)	Fenitoína libre:Concentración de masa:Punto temporal:Suero o Plasma:Qn: Synonyms: Cuantitativo
et-EE	Estonian (Estonia)	Fenütoiin.vaba:MCnc:Pt:S/P:Qn: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA	French (Canada)	Phénytoïne.libre:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR	French (France)	Diphénylhydantoïne libre:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE	French (Belgium)	Phénytoïne.libre:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT	Italian (Italy)	Fenitoina.libera:MCnc:Pt:Siero/Plasma:Qn: Synonyms: Concentrazione di Massa Fenitoina Libera Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR	Korean (Korea, Republic Of)	유리페니토인:질량농도:검사시점:혈청/혈장:정량:
nl-NL	Dutch (Netherlands)	fenytoïne.vrij:massa/volume:moment:serum of plasma:kwantitatief:
pt-BR	Portuguese (Brazil)	Fenitoína.livre:MCnc:Pt:Sor/Plas:Qn: Synonyms: Diphenylhydantoin; Dilantin; DPH; Dilj; DI-HYDAN; Epanutin; Fenantoin; Lehydan; Phenhydan; Sinergina; Zentropil; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Drugs; FR; Non-protein bound; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU	Russian (Russian Federation)	Фенитоин.свободный:МассКонц:ТчкВрм:Сыв/Плаз:Колич: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	Fenitoin.serb:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CN	Chinese (China)	苯妥英.游离型:质量浓度:时间点:血清/血浆:定量型: Synonyms: C15H12N2O2;二苯乙内酰脲;苯妥营;二苯基乙内酰脲;二苯尿囊素可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间毒品毒品类水平;浓度;质量浓度(单位体积) 游离游离型苯妥英;游离苯妥英;苯妥英.游离;苯妥英（二苯乙内酰脲、二苯基乙内酰脲、二苯尿囊素、苯妥营）.游离型药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类血清或血浆非蛋白结合型非蛋白质结合型

Example Units

Unit	Source
mcg/mL	REGENSTRIEF
ug/mL	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=3969-3

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.