40554-8

CD45 Ag [Presence] in Tissue by Immune stain

Active

Part Descriptions

LP20019-3 CD45
Found on alll leukocytes. Absent on erythrocytes.
May be reduced/absent in ALL, Lymphoblastic lymphoma, large cell anaplastic lymphoma, immunoblastic lymphoma, plasma cell proliferations Source: Regenstrief Institute

LP20019-3 CD45
In immunology, the CD45 antigen (CD stands for cluster of differentiation) is a protein which was originally called leukocyte common antigen.

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, CD45

LOINC Names Get Info

Fully-Specified Name: CD45 Ag:PrThr:Pt:Tiss:Ord:Immune stain
Long Common Name: CD45 Ag [Presence] in Tissue by Immune stain
Short Name: CD45 Ag Tiss Ql ImStn
Display Name: CD45 Ag Immune stain Ql (Tiss)
Consumer Name Alpha Get Info: CD45 antigen, Tissue

Part Model Get Info

Component
CD45 Ag
LP37567-2
- Analyte
  CD45 Ag
  LP37567-2
  - Component Numerator
    CD45 Ag
    LP37567-2
    - Component Numerator Core
      CD45
      LP20019-3
    - Component Numerator Core Suffix
      Ag
      LP20666-1
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Tiss
LP7641-6
- System Core
  Tiss
  LP7641-6
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Immune stain
LP6333-1

Basic Attributes

Class: CELLMARK
Type: Laboratory
First Released: Version 2.15
Last Updated: Version 2.73 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both
Common Test Rank Get Info: 15120

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	CD45 Ag:Přítomnost nebo práh:Časový bod:Tkáně a stěry:Ordinální:Imunobarvení
el-GR	Greek (Greece)	CD45 Αντιγόνο:PrThr:Pt:Ιστός:Ord:Ανοσολογική χρώση Synonyms: CD45 CELLMARK Ord PrThr Pt Ανοσολογική χρώση Αντιγόνο Ιστός
es-ES	Spanish (Spain)	CD45 Antígeno:PrThr:Punto temporal:Tejido:Ord:Tinción de inmunohistoquímica
es-MX	Spanish (Mexico)	CD45 Ag:Presencia o umbral:Punto temporal:Tejido y frotis:Ordinal:Mancha inmune
et-EE	Estonian (Estonia)	CD45 antigeen:PrThr:Pt:Tis:Ord:Immuunvärv Synonyms: Järgarvuline Juhuslik Kude
fr-CA	French (Canada)	CD45, Ag:Présence-Seuil:Temps ponctuel:Tissu:Ordinal:Coloration immunologique
fr-FR	French (France)	CD45 Ag:Présence/Seuil:Ponctuel:Tissu:Qualitatif:Coloration immune
fr-BE	French (Belgium)	CD45 Ag:PrThr:Temps ponctuel:Tissu:Ordinal:Coloration immunologique Synonyms: Antigène Coloration. Méthode mmunologique
it-IT	Italian (Italy)	CD45, Ag:PrThr:Pt:Tessuto:Ord:Colorazione immunologica Synonyms: Modelli di superficie cellulare Presenza o Soglia Punto nel tempo (episodio) Tessuto & Strisci
ko-KR	Korean (Korea, Republic Of)	CD45 항원:임의농도:검사시점:조직:순위척도:면역염색
nl-NL	Dutch (Netherlands)	CD45 Ag:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:immunokleuring Synonyms: antigeen
pl-PL	Polish (Poland)	CD45 Ag:granica wykrywalności:punkt w czasie:tkanka i rozmazy:uporządkowany:barwienie immunohistochemiczne Synonyms: Antygen CD45 CD45
pt-BR	Portuguese (Brazil)	CD45 Ag:ACnc:Pt:Tecido:Ord:Imunocoloração Synonyms: CD45RO; CD45RB; CD45RA; LCA; B220; CD45R; CD45RC; Leukocyte common antigen; T200; Ly5; Arbitrary concentration; Point in time; Random; Tissue; Ql; Ordinal; QL; Qualitative; Qual; Screen; ImStn; Immunostain; Immunohistochemical stain; IHC; Antigen; Antigens; Imun; Imune; Imm; CELL MARKERS
ru-RU	Russian (Russian Federation)	CD45 Аг:PrThr:ТчкВрм:Тк:Пор:Иммуногистохимическая окраска Synonyms: Порядковый Ткань и мазки Точка во времени;Момент
tr-TR	Turkish (Turkey)	CD45 Ag:MevcEşik:Zmlı:Doku:Srl:İmmün boyama Synonyms: Antijen Mevcut
zh-CN	Chinese (China)	CD45 抗原:存在情况或阈值:时间点:组织与涂片:序数型:免疫染色法 Synonyms: Ag B220;CD45R;CD45RA;CD45RB;CD45RC;CD45RO;LCA;Ly5;T200;白细胞共同 Ag;白细胞共同分化 Ag;白细胞共同分化抗原;白细胞共同抗原 CD45 Ag 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫染色;免疫组化;免疫组化染色;免疫组化染色法;免疫组化法;免疫组织化学染色;免疫组织化学染色法;细胞免疫染色;细胞免疫染色法存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间未作说明的组织;组织;组织 & 涂片染法染色方法染色法着色着色方法着色法细胞标志物

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.